Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7044

Name

LEFTY2

Synonym

EBAF|LEFTA|LEFTYA|TGFB4;left-right determination factor 2;LEFTY2;left-right determination factor 2

Definition

TGF-beta-4|endometrial bleeding-associated factor|left-right determination factor A|protein lefty-2|protein lefty-A|transforming growth factor beta-4

Position

1q42.1

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

9800

TUSON P-value

1

Pathways and Diseases

Pathway

TGF-beta signaling pathway;KEGG PATHWAY;hsa04350

Pathway

TGF-beta signaling pathway;PANTHER;P00052

Pathway

Hemostasis;Reactome;REACT:604

Disease

Left-right axis malformations;OMIM

External Links

Links to Entrez Gene

7044

Links to all GeneRIF Items

7044

Links to iHOP

7044

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>7044 : length: 999
atgtggcccctgtggctctgctgggcactctgggtgctgcccctggctggccccggggcg
gccctgaccgaggagcagctcctgggcagcctgctgcggcagctgcagctcagcgaggtg
cccgtactggacagggccgacatggagaagctggtcatccccgcccacgtgagggcccag
tatgtagtcctgctgcggcgcagccacggggaccgctcccgcggaaagaggttcagccag
agcttccgagaggtggccggcaggttcctggcgtcggaggccgcgctgcacaggcacggg
cggctgtccccgcgcagcgcccaggcccgggtgaccgtcgagtggctgcgcgtccgcgac
gacggctccaaccgcacctccctcatcgactccaggctggtgtccgtccacgagagcggc
tggaaggccttcgacgtgaccgaggccgtgaacttctggcagcagctgagccggccccgg
cagccgctgctgctacaggtgtcggtgcagagggagcatctgggcccgctggcgtccggc
gcccacaagctggtccgctttgcctcgcagggggcgccagccgggcttggggagccccag
ctggagctgcacaccctggacctcagggactatggagctcagggcgactgtgaccctgaa
gcaccaatgaccgagggcacccgctgctgccgccaggagatgtacattgacctgcagggg
atgaagtgggccaagaactgggtgctggagcccccgggcttcctggcttacgagtgtgtg
ggcacctgccagcagcccccggaggccctggccttcaattggccatttctggggccgcga
cagtgtatcgcctcggagactgcctcgctgcccatgatcgtcagcatcaaggagggaggc
aggaccaggccccaggtggtcagcctgcccaacatgagggtgcagaagtgcagctgtgcc
tcggatggggcgctcgtgccaaggaggctccagccatag

Protein Sequence

>7044 : length: 332
MWPLWLCWALWVLPLAGPGAALTEEQLLGSLLRQLQLSEVPVLDRADMEKLVIPAHVRAQ
YVVLLRRSHGDRSRGKRFSQSFREVAGRFLASEAALHRHGRLSPRSAQARVTVEWLRVRD
DGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASG
AHKLVRFASQGAPAGLGEPQLELHTLDLRDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQG
MKWAKNWVLEPPGFLAYECVGTCQQPPEALAFNWPFLGPRQCIASETASLPMIVSIKEGG
RTRPQVVSLPNMRVQKCSCASDGALVPRRLQP



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