| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7056 |
Name | THBD |
Synonym | AHUS6|BDCA3|CD141|THPH12|THRM|TM;thrombomodulin;THBD;thrombomodulin |
Definition | CD141 antigen|fetomodulin |
Position | 20p11.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16428 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | Common Pathway;PID Reactome;500303 |
Pathway | Blood coagulation;PANTHER;P00011 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Pathway | Hemostasis;Reactome;REACT:604 |
Disease | Hematologic diseases;KEGG DISEASE |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | Thrombophilia due to thrombomodulin defect;OMIM |
Disease | atherosclerosis, coronary;GAD |
Disease | cerebral infarct;GAD |
Disease | thrombosis, deep vein;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | acute myocardial infarction;GAD |
Disease | Myocardial Infarction;GAD |
Disease | Hemolytic uremic syndrome, atypical, susceptibility to, 6;OMIM |
Disease | Atherosclerosis;GAD |
Disease | Myocardial infarction, susceptibility to;OMIM |
Disease | Inherited thrombophilia;KEGG DISEASE;H00223 |
|
External Links |
|
Links to Entrez Gene | 7056 |
Links to all GeneRIF Items | 7056 |
Links to iHOP | 7056 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7056 : length: 1728 atgcttggggtcctggtccttggcgcgctggccctggccggcctggggttccccgcaccc gcagagccgcagccgggtggcagccagtgcgtcgagcacgactgcttcgcgctctacccg ggccccgcgaccttcctcaatgccagtcagatctgcgacggactgcggggccacctaatg acagtgcgctcctcggtggctgccgatgtcatttccttgctactgaacggcgacggcggc gttggccgccggcgcctctggatcggcctgcagctgccacccggctgcggcgaccccaag cgcctcgggcccctgcgcggcttccagtgggttacgggagacaacaacaccagctatagc aggtgggcacggctcgacctcaatggggctcccctctgcggcccgttgtgcgtcgctgtc tccgctgctgaggccactgtgcccagcgagccgatctgggaggagcagcagtgcgaagtg aaggccgatggcttcctctgcgagttccacttcccagccacctgcaggccactggctgtg gagcccggcgccgcggctgccgccgtctcgatcacctacggcaccccgttcgcggcccgc ggagcggacttccaggcgctgccggtgggcagctccgccgcggtggctcccctcggctta cagctaatgtgcaccgcgccgcccggagcggtccaggggcactgggccagggaggcgccg ggcgcttgggactgcagcgtggagaacggcggctgcgagcacgcgtgcaatgcgatccct ggggctccccgctgccagtgcccagccggcgccgccctgcaggcagacgggcgctcctgc accgcatccgcgacgcagtcctgcaacgacctctgcgagcacttctgcgttcccaacccc gaccagccgggctcctactcgtgcatgtgcgagaccggctaccggctggcggccgaccaa caccggtgcgaggacgtggatgactgcatactggagcccagtccgtgtccgcagcgctgt gtcaacacacagggtggcttcgagtgccactgctaccctaactacgacctggtggacggc gagtgtgtggagcccgtggacccgtgcttcagagccaactgcgagtaccagtgccagccc ctgaaccaaactagctacctctgcgtctgcgccgagggcttcgcgcccattccccacgag ccgcacaggtgccagatgttttgcaaccagactgcctgtccagccgactgcgaccccaac acccaggctagctgtgagtgccctgaaggctacatcctggacgacggtttcatctgcacg gacatcgacgagtgcgaaaacggcggcttctgctccggggtgtgccacaacctccccggt accttcgagtgcatctgcgggcccgactcggcccttgcccgccacattggcaccgactgt gactccggcaaggtggacggtggcgacagcggctctggcgagcccccgcccagcccgacg cccggctccaccttgactcctccggccgtggggctcgtgcattcgggcttgctcataggc atctccatcgcgagcctgtgcctggtggtggcgcttttggcgctcctctgccacctgcgc aagaagcagggcgccgccagggccaagatggagtacaagtgcgcggccccttccaaggag gtagtgctgcagcacgtgcggaccgagcggacgccgcagagactctga |
Protein Sequence |
>7056 : length: 575 MLGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLM TVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYS RWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAV EPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAP GAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNP DQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDG ECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPN TQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDC DSGKVDGGDSGSGEPPPSPTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLR KKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL |