| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 7068 |
Name | THRB |
Synonym | C-ERBA-2|C-ERBA-BETA|ERBA2|GRTH|NR1A2|PRTH|THR1|THRB1|THRB2;thyroid hormone receptor, beta;THRB;thyroid hormone receptor, beta |
Definition | nuclear receptor subfamily 1 group A member 2|oncogene ERBA2|thyroid hormone nuclear receptor beta variant 1|thyroid hormone receptor beta|thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
Position | 3p24.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16451 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | map kinase inactivation of smrt corepressor;PID BioCarta;100032 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Gene Expression;Reactome;REACT:71 |
Disease | Thyroid hormone resistance;OMIM |
Disease | PSYCH;GAD |
Disease | ADHD;GAD |
Disease | Thyroid hormone resistance, selective pituitary;OMIM |
Disease | IMMUNE;GAD |
Disease | Thyroid hormone resistance, autosomal recessive;OMIM |
Disease | Hematological and biochemical traits;NHGRI |
Disease | METABOLIC;GAD |
Disease | Graves disease;GAD |
Disease | resistance to thyroid hormone;GAD |
Disease | hormone disturbance;GAD |
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External Links |
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Links to Entrez Gene | 7068 |
Links to all GeneRIF Items | 7068 |
Links to iHOP | 7068 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7068 : length: 1386 atgactcccaacagtatgacagaaaatggccttacagcctgggacaaaccgaagcactgt ccagaccgagaacacgactggaagctagtaggaatgtctgaagcctgcctacataggaag agccattcagagaggcgcagcacgttgaaaaatgaacagtcgtcgccacatctcatccag accacttggactagctcaatattccatctggaccatgatgatgtgaacgaccagagtgtc tcaagtgcccagaccttccaaacggaggagaagaaatgtaaagggtacatccccagttac ttagacaaggacgagctctgtgtagtgtgtggtgacaaagccaccgggtatcactaccgc tgtatcacgtgtgaaggctgcaagggtttctttagaagaaccattcagaaaaatctccat ccatcctattcctgtaaatatgaaggaaaatgtgtcatagacaaagtcacgcgaaatcag tgccaggaatgtcgctttaagaaatgcatctatgttggcatggcaacagatttggtgctg gatgacagcaagaggctggccaagaggaagctgatagaggagaaccgggagaaaagacgg cgggaagagctgcagaagtccatcgggcacaagccagagcccacagacgaggaatgggag ctcatcaaaactgtcaccgaagcccatgtggcgaccaacgcccaaggcagccactggaag caaaaacggaaattcctgccagaagacattggacaagcaccaatagtcaatgccccagaa ggtggaaaggttgacttggaagccttcagccattttacaaaaatcatcacaccagcaatt accagagtggtggattttgccaaaaagttgcctatgttttgtgagctgccatgtgaagac cagatcatcctcctcaaaggctgctgcatggagatcatgtcccttcgcgctgctgtgcgc tatgacccagaaagtgagactttaaccttgaatggggaaatggcagtgacacggggccag ctgaaaaatgggggtcttggggtggtgtcagacgccatctttgacctgggcatgtctctg tcttctttcaacctggatgacactgaagtagccctccttcaggccgtcctgctgatgtct tcagatcgcccggggcttgcctgtgttgagagaatagaaaagtaccaagatagtttcctg ctggcctttgaacactatatcaattaccgaaaacaccacgtgacacacttttggccaaaa ctcctgatgaaggtgacagatctgcggatgataggagcctgccatgccagccgcttcctg cacatgaaggtggaatgccccacagaactcttcccccctttgttcttggaagtgttcgag gattag |
Protein Sequence |
>7068 : length: 461 MTPNSMTENGLTAWDKPKHCPDREHDWKLVGMSEACLHRKSHSERRSTLKNEQSSPHLIQ TTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYR CITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVL DDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWK QKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCED QIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSL SSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPK LLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED |