General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 8313 |
Name | AXIN2 |
Synonym | AXIL|ODCRCS;axin 2;AXIN2;axin 2 |
Definition | axin-2|axin-like protein|axis inhibition protein 2|conductin |
Position | 17q24.1 |
Gene Type | protein-coding |
TSG scores |
Description |
TUSON ranking | 1618 |
TUSON P-value | 0.116935031 |
Pathways and Diseases |
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Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Regulation of Wnt-mediated beta catenin signaling and target gene transcription;PID Curated;200106 |
Pathway | Canonical Wnt signaling pathway;PID Curated;200064 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Disease | Oligodontia-colorectal cancer syndrome;OMIM |
Disease | Colorectal cancer;OMIM |
External Links |
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Links to Entrez Gene | 8313 |
Links to all GeneRIF Items | 8313 |
Links to iHOP | 8313 |
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8313 : length: 2532 atgagtagcgctatgttggtgacttgcctcccggaccccagcagcagcttccgtgaggat gccccgcggcccccagtgccaggggaagaaggggagaccccaccgtgtcagccaggggtg ggcaagggccaggtcaccaaacccatgcctgtctcttccaacaccaggcggaacgaagat gggttgggggagccggaggggcgggcatctccggattcccctctgacccggtggaccaag tccttacactccttattgggcgatcaagacggtgcttacctgttccgaactttcctggag agggagaaatgcgtggataccttagacttctggtttgcctgcaatggattcaggcagatg aacctgaaggataccaaaactttacgagtagccaaagcgatctacaaaaggtacattgag aacaacagcattgtctccaagcagctgaagcctgccaccaagacctacataagagatggc atcaagaagcagcagattgattccatcatgtttgaccaggcgcagaccgagatccagtcg gtgatggaggaaaatgcctaccagatgtttttgacttctgatatatacctcgaatatgtg aggagtgggggagaaaacacagcttacatgagtaatgggggactcgggagcctaaaggtc gtgtgtggctatctccccaccttgaatgaagaagaggagtggacttgtgccgacttcaag tgcaaactttcgccaaccgtggttggcttgtccagcaaaactctgagggccacggcgagt gtgaggtccacggaaactgttgacagtggatacaggtccttcaagaggagcgatcctgtt aatccttatcacataggttctggctatgtctttgcaccagccaccagcgccaacgacagt gagatatccagtgatgcgctgacggatgattccatgtccatgacggacagcagtgtagat ggaattcctccttatcgtgtgggcagtaagaaacagctccagagagaaatgcatcgcagt gtgaaggccaatggccaagtgtctctacctcatttcccgagaacccaccgcctgcccaag gagatgacccccgtggaacccgccacctttgcagctgagctgatctcgaggctggaaaag ctgaagctggagttggagagccgccacagcctggaggagcgcctgcagcagatccgagag gatgaagagagagagggctccgagctcacactcaattcgcgggagggggcgcccacgcag caccccctctccctactgccctccggcagctacgaggaagacccgcagacgatactggac gatcacctgtccagggtcctcaagacccctggctgccagtctccaggcgtaggccgctat agcccccgctcccgctccccggaccaccaccaccaccaccattcgcagtaccactccctg ctcccgcccggtggcaagctgcctcccgcggccgcctcgccgggcgcctgccccctcctc gggggcaaaggctttgtgaccaagcagacgacgaagcatgtccaccaccactacatccac caccatgccgtccccaagaccaaggaggagatcgaggcggaggccacgcagcgggtgcac tgcttctgccctgggggcagcgagtattactgctactcgaaatgcaaaagccactccaag gctccggaaaccatgcccagcgagcagtttggcggcagcagaggcagtaccttgcccaaa cgcaatgggaaaggcacggagccgggcctggccctgcccgccagggaaggaggggccccc ggcggagctggggccctgcagcttccccgggaggaaggagacaggtcgcaggatgtctgg cagtggatgctggagagtgagcggcagagcaagcccaagccccatagtgcccaaagcaca aaaaaggcctaccccttggagtctgcccgctcgtctccaggcgaacgagccagccggcac catctgtgggggggcaacagcgggcacccccgcaccaccccccgtgcccacctgttcacc caggaccctgcgatgcctcccctgaccccacccaacacgctggctcagctggaggaggcc tgtcgcaggctagctgaggtgtcgaagcccccaaagcagcggtgctgtgtggccagtcag cagagggacaggaatcattcggccactgttcagacgggagccacacccttctccaatcca agcctggctccagaagatcacaaagagccaaagaaactggcaggtgtccacgcgctccag gccagtgagttggttgtcacttactttttctgtggggaagaaattccataccggaggatg ctgaaggctcagagcttgaccctgggccactttaaagagcagctcagcaaaaagggaaat tataggtattacttcaaaaaagcaagcgatgagtttgcctgtggagcggtgtttgaggag atctgggaggatgagacggtgctcccgatgtatgaaggccggattctgggcaaagtggag cggatcgattga |
Protein Sequence |
>8313 : length: 843 MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGETPPCQPGVGKGQVTKPMPVSSNTRRNED GLGEPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQM NLKDTKTLRVAKAIYKRYIENNSIVSKQLKPATKTYIRDGIKKQQIDSIMFDQAQTEIQS VMEENAYQMFLTSDIYLEYVRSGGENTAYMSNGGLGSLKVVCGYLPTLNEEEEWTCADFK CKLSPTVVGLSSKTLRATASVRSTETVDSGYRSFKRSDPVNPYHIGSGYVFAPATSANDS EISSDALTDDSMSMTDSSVDGIPPYRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPK EMTPVEPATFAAELISRLEKLKLELESRHSLEERLQQIREDEEREGSELTLNSREGAPTQ HPLSLLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHHHHSQYHSL LPPGGKLPPAAASPGACPLLGGKGFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVH CFCPGGSEYYCYSKCKSHSKAPETMPSEQFGGSRGSTLPKRNGKGTEPGLALPAREGGAP GGAGALQLPREEGDRSQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRH HLWGGNSGHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQ QRDRNHSATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRM LKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVE RID |