| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 8379 |
Name | MAD1L1 |
Synonym | MAD1|PIG9|TP53I9|TXBP181;MAD1 mitotic arrest deficient-like 1 (yeast);MAD1L1;MAD1 mitotic arrest deficient-like 1 (yeast) |
Definition | MAD1-like protein 1|mitotic arrest deficient 1-like protein 1|mitotic checkpoint MAD1 protein homolog|mitotic spindle assembly checkpoint protein MAD1|mitotic-arrest deficient 1, yeast, homolog-like 1|tax-binding protein 181|tumor protein p53 inducible pr |
Position | 7p22 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 10198 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal;PID Reactome;500325 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | DNA Replication;Reactome;REACT:383 |
Disease | Neoplasm Recurrence, Local;GAD |
Disease | Carcinoma, Hepatocellular;GAD |
Disease | Prostate cancer, somatic;OMIM |
Disease | Lymphoma, somatic;OMIM |
Disease | CANCER;GAD |
Disease | Liver Neoplasms;GAD |
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External Links |
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Links to Entrez Gene | 8379 |
Links to all GeneRIF Items | 8379 |
Links to iHOP | 8379 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8379 : length: 2157 atggaagacctgggggaaaacaccatggttttatccaccctgagatctttgaacaacttc atctctcagcgtgtggagggaggctctggactggatatttctacctcggccccaggttct ctgcagatgcagtaccagcagagcatgcagctggaggaaagagcagagcagatccgttcg aagtcccacctcatccaggtggagcgggagaaaatgcagatggagctgagtcacaagagg gctcgagtggagctggagagagcagccagcaccagtgccaggaactacgagcgtgaggtc gaccgcaaccaggagctcctgacgcgcatccggcagcttcaggagcgggaggccggggcg gaggagaagatgcaggagcagctggagcgcaacaggcagtgtcagcagaacttggatgct gccagcaagaggctgcgtgagaaagaggacagtctggcccaggctggcgagaccatcaac gcactgaaggggaggatctcggaactgcagtggagcgtgatggaccaggagatgcgggtg aagcgcctggagtcggagaagcaggagctgcaggagcagctggacctgcaacacaaaaaa tgccaggaagccaatcagaaaatccaggaactccaggccagccaagaagcaagagcagac cacgagcagcagattaaggatctggagcagaagctgtccctgcaagagcaggatgcagcg attgtgaagaacatgaagtctgagctggtacggctccctaggctggaacgggagctgaag cagctgcgggaggagagcgcgcacctgcgggagatgagagagaccaacgggctgctccag gaagagctggaagggctgcagaggaagctggggcgccaggagaagatgcaggagacgctg gttggcttggagctggagaacgagaggctgctggccaagctgcaaagctgggagagactg gaccagaccatgggcctgagcatcaggactccagaagacctttccagattcgtggttgag ctgcagcagagggagcttgccttgaaggacaagaacagcgccgtcaccagcagcgcccgg gggctggagaaggccaggcagcagctgcaggaggagctccggcaggtcagcggccagctg ttggaggagaggaagaagcgcgagacccacgaggcgctggcccggaggctccagaaacgg gtcctgctgctcaccaaggagcgggacggtatgcgggccatcctggggtcctacgacagc gagctgaccccggccgagtactcaccccagctgacgcggcgcatgcgggaggctgaggat atggtgcagaaggtgcacagccacagcgccgagatggaggctcagctgtcgcaggccctg gaggagctgggaggccagaaacaaagagcagacatgctggagatggagctgaagatgctg aagtctcagtccagctctgccgaacagagcttcctgttctccagggaggaggcggacacg ctcaggttgaaggtcgaggagctggaaggcgagcggagtcggctggaggaggaaaagagg atgctggaggcacagctggagcggcgagctctgcagggtgactatgaccagagcaggacc aaagtgctgcacatgagcctgaaccccaccagtgtggccaggcagcgcctgcgcgaggac cacagccagctgcaggcggagtgcgagcgactgcgcgggctcctgcgcgccatggagaga ggaggcaccgtcccagccgaccttgaggctgccgccgcgagtctgccatcgtccaaggag gtggcagagctgaagaagcaggtggagagtgccgagctgaagaaccagcggctcaaggag gttttccagaccaagatccaggagttccgcaaggcctgctacacgctcaccggctaccag atcgacatcaccacggagaaccagtaccggctgacctcgctgtacgccgagcacccaggc gactgcctcatcttcaaggccaccagcccctcgggttccaagatgcagctactggagaca gagttctcacacaccgtgggcgagctcatcgaggtgcacctgcggcgccaggacagcatc cctgccttcctcagctcgctcaccctcgagctcttcagccgccagaccgtggcgtag |
Protein Sequence |
>8379 : length: 718 MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRS KSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGA EEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRV KRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAA IVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETL VGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSAR GLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDS ELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKML KSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRT KVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKE VAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPG DCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA |