Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

84700

Name

MYO18B

Synonym

-;myosin XVIIIB;MYO18B;myosin XVIIIB

Definition

myosin 18B|myosin-XVIIIb|unconventional myosin-XVIIIb

Position

22q12.1

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

11041

TUSON P-value

1

Pathways and Diseases

Pathway

Nicotinic acetylcholine receptor signaling pathway;PANTHER;P00044

Disease

Schizophrenia, bipolar disorder and depression (combined);NHGRI

Disease

smoking cessation;GAD

Disease

CHEMDEPENDENCY;GAD

External Links

Links to Entrez Gene

84700

Links to all GeneRIF Items

84700

Links to iHOP

84700

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>84700 : length: 7704
atggccatctcatcacgcctcgccctgtgggagcagaagattcgggaagaggacaagagc
cctccaccatcctcgccccctcctcttttctctgtcatcccagggggcttcattaagcaa
ctggtccgggggactgaaaaagaggccaaggaagcgagacagaggaagcagttagctgtc
gcctctccagaacgagagatcccagaaatttccatcagccaacccaacagcaagtccagc
agtggcaccagatctggaagccagcagatctctcaggacgaccagtcaagctctcctggg
agctcagacattctgggcaaggagagcgaggggtcccgcagccccgaccctgagcagatg
acaagcatcaatggtgagaaggcccaggagctgggctccagtgcgacaccaaccaaaaag
actgtccccttcaagaggggcgtgaggaggggtgatgtgttgttgatggtggccaagctg
gacccggactcagccaagccagagaagactcatccccatgacgcccccccttgcaagacc
tctccccccgccacagatactggaaaggaaaagaaaggggagacctctaggactccttgt
ggctcccaggccagcaccgagatcttggccccgaaagctgagaagacccggactgggggt
cttggggacccaggccaaggaactgtggcactgaaaaaaggcgaggagggtcaaagcata
gtggggaaggggcttgggacccccaagaccacagagctgaaagaggctgagccccagggc
aaagacaggcaggggaccaggccccaagcccaagggcccggcgagggggtgcgaccaggg
aaagcagagaaggagggagcagagcccacaaacacggtggaaaaggggaatgtctctaag
gacgtagggagtgaagggaagcacgtaaggccccaaatccctgggagaaagtggggaggt
ttcctgggaagaaggagtaagtgggacggtccccagaataagaaggacaaagaaggggtg
ctcttaagtaaggcagagaagacaggtgagcctcagacccagatggagaagacaagccaa
gtgcagggcgagttgggggacgatctgagaatgggggagaaagcaggtgagcttcggagc
acgactgggaaggcaggtgagtcctgggataagaaggaaaagatggggcaaccccagggt
aagtccgggaacgcaggtgaagctcggagtcagacagagaagggctgtgaagccccaaag
gaggtgagcacaatggtggagtcgccagcagctcctgggaagggaggctggccaggaagc
cgtgggcaggaagcagaggagccctgctcaagagcaggtgatggggctggtgccctggag
acagagctggaaggacccagccagcctgctctggagaaggatgcagaaaggcctcggata
cggaaggagaaccaagacgggccagccccgcaggaggagggcaaaggaggccagagcaga
gactcagaccaggctcctgaggacagatggtatgaggcagagaaagtctggctggctcag
aaggatggatttactcttgctacggtgctaaagccagatgagggaacagcagacctgcca
gcaggaagggtgagactttggattgatgctgacaaaaccatcactgaggtggatgaggag
catgtccatcgggccaaccctcctgagctggaccaggtcgaggacctggcctctctcatc
agtgtcaacgaatccagtgtcctgaacacgcttctgcagcgctacaaagctcagctgctg
cacacctgcacagggcctgatctgattgtcctccagccccgggggccctcggtgccttct
gcagggaaggtgcccaagggccgccgggatggcctgcctgcccacattggctccatggca
cagcgggcatactgggcgctgctgaaccagcggagagaccagagcattgtggccctgggc
tggagtggcgctgggaagaccacctgctgtgagcaggtcctggaacacctggtggggatg
gcaggcagtgtggatggcagggtctcagtggagaagatccgagccaccttcactgtcctc
cgggccttcggctctgtgtccatggcccacagccgcagtgccacccggttctccatggtg
atgtcgctggacttcaacgctacaggccgcatcacagctgctcagctccagacaatgctt
ttggagaagagccgcgtggcacggcagccggaaggggaaagtaacttcctggttttctcc
cagatgctggctggattggacttggatctcaggacggagctgaacctgcaccagatggca
gatagcagctcctttggcatgggcgtgtggtccaagcctgaagataaacagaaggcggca
gctgcctttgcccagctccagggtgccatggagatgctcggcatctcagagagcgagcag
cgggctgtttggcgggtcctggcagccatctaccacctgggtgcggcgggggcctgcaaa
gtgggtcggaagcagttcatgaggtttgagtgggcaaactacgcagctgaggccctgggc
tgcgagtatgaggagctgaacacggccaccttcaagcaccaccttcgacagatcatccag
caaatgacgtttgggccaagccgatggggcctcgaggatgaggaaaccagctcagggctc
aagatgacaggagtggactgtgtggaggggatggcctcgggcctgtaccaggaactcttt
gcggctgtggtctcactcatcaacagatccttttcctcccaccatctctccatggcctcc
atcatggtggtggactctccaggcttccagaacccccggcaccagggcaaggaccgggcg
gccacctttgaggagctgtgccacaactacgcccatgagcgcctgcagctgctgttctac
cagcggacctttgtctccacgctacagcgatatcaagaggaaggtgttcctgtgcagttt
gacctcccggacccctccccagggaccaccgtggctgttgtggatcaaaatccctctcag
gtccgcttaccagctggaggaggtgcccaggatgccagaggccttttctgggtcttagat
gaggaagtccatgtagagggctccagtgacagtgtggtgctcgagcgtctgtgtgctgct
ttcgagaagaaaggagctgggactgaagggtcctctgccctgcggacctgtgagcagccc
ctccagtgtgagattttccaccagttgggatgggaccctgtgcggtacgacctcacgggc
tggctccacagagccaagcccaacctctcggccctggatgcaccccaggtcctgcaccag
tcaaaaagagaggagctgcggagtctattccaggcccgggccaagctgcctcctgtgtgc
cgggctgtggcaggcctggagggcacctcccagcaggccctgcagaggagccgcatggtg
aggaggacctttgccagcagccttgccgcggtgaggaggaaagccccgtgctcccagatc
aagctgcagatggatgcgctgaccagcatgatcaaaaggtcccggctgcactttatccac
tgcctggtaccaaaccctgtggtggaaagcaggagtgggcaggaatctccaccaccaccg
cagcctggtagagacaagcctggggcaggtggacctctggccctggatatcccagcactg
agggtccagcttgctgggttccacatcctggaggctctgcgtctgcataggacaggctat
gctgaccacatggggctcactcgcttccgccggcaattccaggtgctggacgctccactc
ctgaagaagctcatgtcgacctccgagggaatagatgaaaggaaggccgtggaggagctc
ctggagaccctggatctggaaaagaaggcggtggctgtggggcacagccaagtttttctc
aaggcaggtgtgatctccaggcttgagaagcagcgagagaagctggtatctcagagcatc
gttctcttccaggcggcttgcaagggctttctgtctcgccaggaattcaagaagctgaag
attcgccgactggctgcacagtgcatccagaagaatgtggctgtgttcctcgcagtcaag
gactggccatggtggcagctgcttggttccctccagcctctacttagtgccaccattgga
actgagcagctccgagccaaggaggaggagcttacaacgctaagacggaagctagaaaaa
tcagagaagttgcggaatgaactccggcagaacacagatctgctagaaagcaagattgct
gacttgacctctgaccttgccgatgagcgcttcaaaggtgatgtggcctgccaggtgctg
gagagtgagcgggcagagcggctacaggccttccgggaggtccaggagctcaagagcaag
catgaacaagtccagaaaaaactgggagatgtgaataaacagttggaagaagcccagcag
aaaattcagttgaatgacttggaaaggaatcccactggaggagcagacgagtggcagatg
cgcttcgactgtgctcagatggagaacgagttcctcagaaagcgtctgcagcaatgcgag
gagaggctggactcggagctgacagccaggaaagagctggagcaaaagcttggggagttg
caaagtgcttatgacggggccaagaagatggctcaccaactgaagaggaagtgccaccat
cttacctgtgaccttgaggatacctgcgtcctgctagagaaccaacaaagtcgaaaccat
gagctggagaagaagcagaagaagtttgacctgcagctggcccaggccctaggtgagtca
gtgtttgagaagggtctccgtgagaaagtgacccaggagaacaccagtgtccggtgggag
ctaggccagcttcagcagcagctgaagcaaaaggagcaggaagcctcacagctgaagcag
caggtggagatgctacaggaccataaacgggagctgctggggtcaccctctctgggggaa
aattgcgttgctggcttgaaggagaggctctggaagttggaatccagcgcccttgagcaa
cagaaaatccagagccagcaggaaaacaccatcaagcagctggagcagctccgccagcgg
tttgagctggagatcgagcggatgaagcagatgcaccagaaggaccgtgaggaccaggag
gaggaactggaggatgtccgtcagtcctgccagaagcggcttcatcagctggaaatgcag
ctggagcaagagtatgaagagaagcagatggtcctccatgagaagcaagatttggaaggc
ttgatcggaaccctctgtgaccagattggccatcgggactttgatgtggagaagcgactt
cggagagacctcaggaggacacatgcactgttgtcagacgtgcagctccttctgggcacc
atggaggatggcaagacatcagtcagcaaggaggagctggagaaagtgcacagccagctg
gagcagagtgaagccaagtgtgaggaggccttgaagacgcagaaggtgctcacagcggac
ctggagagcatgcacagcgagctggagaacatgacgcggaacaagagcctggtggatgag
cagctgtacaggctgcagtttgagaaggcggacctcctgaagcgcatcgatgaggaccag
gatgacctgaatgagctgatgcagaagcacaaggacctcattgctcagtctgctgctgac
attgggcagatccaagaactgcagctgcagctggaggaagccaagaaggagaagcacaag
ctacaagaacaactgcaggtggctcagatgcgcatcgagtacctggaacagtccaccgtg
gatcgagccatcgtcagcaggcaggaggcggtcatctgtgacctagagaacaagacagag
ttccagaaggtgcagattaagagatttgaggtcctggtgatccggcttcgggacagcctg
atcaagatgggggaggagctttcacaggcggccacctccgagtcccagcagcgggagagc
agccagtactaccagcggcgcctggaagagctgaaggccgacatggaagagctggtgcag
cgggaggcagaggccagccggcggtgcatggagctggagaagtacgtggaggaacttgca
gcagtgaggcaaaccctccagacagacctggagacatccattcggcggattgccgacctg
caggctgccttggaagaagtggcatccagtgacagtgatactgagagtgtccagacggca
gtggattgtggcagcagcggccgaaaagagatggataacgtctccatcctcagctcccag
ccagagggcagcctgcagtcctggttgagctgtactctgtccctggccacagatactatg
aggactccttctcgacagtcagccaccagcagccgcatcctcagccccaggataaacgaa
gaggctggggacactgagaggacccagtcggcattggcactgagcagagcccggtccacc
aatgtccacagcaagacctcaggagacaagcctgtttctccccactttgtccgccggcaa
aagtactgtcattttggggacggcgaagtgcttgccgtccagagaaagtccacagagaga
ttagaacctgcttcctctcccctggcttctcggagtacaaatacatccccgctgtcgagg
gaaaagctgcccagtccttcagcggccctctcggagttcgtggaagggctccggaggaag
agagcccagagaggccaggggtccacgctgggcctagaggactggcccactctccccatt
taccagacgactggggcctccacactaaggaggggcagggctggcagtgacgagggaaac
ctctcgctgagggttggggcaaagtcacccctggaaatcgaaggggccgctggtggtctc
ttgaggtccaccagcctcaaatgcatctcttcagacggtgttgggggcacaaccctactc
cccgaaaagtcgaaaacccaattcagttcctgcgagtccctcttagaatccagaccgagc
atggggagaaaactgagctctccgaccacacccagggacatgctgttgtcgcccacactg
cgtcctcggaggcggtgtctggagtcctctgtggacgatgcgggctgtccagaccttgga
aaggagccgcttgttttccagaaccgccagtttgcccacctgatggaggaacctctaggc
agtgacccattcagctggaaactcccaagcctcgactacgaacgcaagaccaaagtggac
ttcgatgacttcctcccagctatccggaagccccagacacctacctccttggctggatca
gccaaaggtgggcaagacggttcacagcgttcaagcatccactttgaaacggaagaggct
aaccgttcctttctctcggggatcaagaccattttgaagaagagcccggagcccaaggag
gatcccgctcacctgtctgactcgtcctcatcctccggctccatcgtgtccttcaaaagt
gctgacagcatcaaaagtcgaccaggaatcccacgacttgcgggtgacggtggcgagcga
acgtcccccgagcggagagagccagggacggggaggaaagacgacgatgttgcgagcata
atgaagaaatacctccagaagtag

Protein Sequence

>84700 : length: 2567
MAISSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRGTEKEAKEARQRKQLAV
ASPEREIPEISISQPNSKSSSGTRSGSQQISQDDQSSSPGSSDILGKESEGSRSPDPEQM
TSINGEKAQELGSSATPTKKTVPFKRGVRRGDVLLMVAKLDPDSAKPEKTHPHDAPPCKT
SPPATDTGKEKKGETSRTPCGSQASTEILAPKAEKTRTGGLGDPGQGTVALKKGEEGQSI
VGKGLGTPKTTELKEAEPQGKDRQGTRPQAQGPGEGVRPGKAEKEGAEPTNTVEKGNVSK
DVGSEGKHVRPQIPGRKWGGFLGRRSKWDGPQNKKDKEGVLLSKAEKTGEPQTQMEKTSQ
VQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGCEAPK
EVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAERPRI
RKENQDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLP
AGRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLL
HTCTGPDLIVLQPRGPSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG
WSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMV
MSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMA
DSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK
VGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGL
KMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRA
ATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQ
VRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQP
LQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVC
RAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIH
CLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGY
ADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFL
KAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVK
DWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIA
DLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQ
KIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGEL
QSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGES
VFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE
NCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQE
EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRL
RRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTAD
LESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTE
FQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQ
REAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINE
EAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTER
LEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLL
PEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLRPRRRCLESSVDDAGCPDLG
KEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKS
ADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIMKKYLQK



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