| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8626 |
Name | TP63 |
Synonym | AIS|B(p51A)|B(p51B)|EEC3|KET|LMS|NBP|OFC8|RHS|SHFM4|TP53CP|TP53L|TP73L|p40|p51|p53CP|p63|p73H|p73L;tumor protein p63;TP63;tumor protein p63 |
Definition | CUSP|amplified in squamous cell carcinoma|chronic ulcerative stomatitis protein|keratinocyte transcription factor KET|transformation-related protein 63|tumor protein 63|tumor protein p53-competing protein|tumor protein p63 deltaN isoform delta |
Position | 3q28 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16936 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | p53 pathway by glucose deprivation;PANTHER;P04397 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | P53 pathway feedback loops 1;PANTHER;P04392 |
Disease | urinary bladder cancer;GAD |
Disease | Rapp-Hodgkin syndrome;OMIM |
Disease | Orofacial cleft 8;OMIM |
Disease | Split-hand/foot malformation, type 4;OMIM |
Disease | Limb-mammary syndrome;OMIM |
Disease | Hay-Wells syndrome;OMIM |
Disease | Lung adenocarcinoma;NHGRI |
Disease | ADULT syndrome;OMIM |
Disease | CANCER;GAD |
Disease | Brain imaging;NHGRI |
Disease | Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3;OMIM |
Disease | Brain imaging;GAD |
Disease | proliferative potential of keratinocytes;GAD |
Disease | Urinary bladder cancer;NHGRI |
Disease | blastic crisis;GAD |
Disease | NEUROLOGICAL;GAD |
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External Links |
|
Links to Entrez Gene | 8626 |
Links to all GeneRIF Items | 8626 |
Links to iHOP | 8626 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>8626 : length: 1668 atgaattttgaaacttcacggtgtgccaccctacagtactgccctgacccttacatccag cgtttcgtagaaaccccagctcatttctcttggaaagaaagttattaccgatccaccatg tcccagagcacacagacaaatgaattcctcagtccagaggttttccagcatatctgggat tttctggaacagcctatatgttcagttcagcccattgacttgaactttgtggatgaacca tcagaagatggtgcgacaaacaagattgagattagcatggactgtatccgcatgcaggac tcggacctgagtgaccccatgtggccacagtacacgaacctggggctcctgaacagcatg gaccagcagattcagaacggctcctcgtccaccagtccctataacacagaccacgcgcag aacagcgtcacggcgccctcgccctacgcacagcccagctccaccttcgatgctctctct ccatcacccgccatcccctccaacaccgactacccaggcccgcacagtttcgacgtgtcc ttccagcagtcgagcaccgccaagtcggccacctggacgtattccactgaactgaagaaa ctctactgccaaattgcaaagacatgccccatccagatcaaggtgatgaccccacctcct cagggagctgttatccgcgccatgcctgtctacaaaaaagctgagcacgtcacggaggtg gtgaagcggtgccccaaccatgagctgagccgtgaattcaacgagggacagattgcccct cctagtcatttgattcgagtagaggggaacagccatgcccagtatgtagaagatcccatc acaggaagacagagtgtgctggtaccttatgagccaccccaggttggcactgaattcacg acagtcttgtacaatttcatgtgtaacagcagttgtgttggagggatgaaccgccgtcca attttaatcattgttactctggaaaccagagatgggcaagtcctgggccgacgctgcttt gaggcccggatctgtgcttgcccaggaagagacaggaaggcggatgaagatagcatcaga aagcagcaagtttcggacagtacaaagaacggtgatggtacgaagcgcccgtttcgtcag aacacacatggtatccagatgacatccatcaagaaacgaagatccccagatgatgaactg ttatacttaccagtgaggggccgtgagacttatgaaatgctgttgaagatcaaagagtcc ctggaactcatgcagtaccttcctcagcacacaattgaaacgtacaggcaacagcaacag cagcagcaccagcacttacttcagaaacagacctcaatacagtctccatcttcatatggt aacagctccccacctctgaacaaaatgaacagcatgaacaagctgccttctgtgagccag cttatcaaccctcagcagcgcaacgccctcactcctacaaccattcctgatggcatggga gccaacattcccatgatgggcacccacatgccaatggctggagacatgaatggactcagc cccacccaggcactccctcccccactctccatgccatccacctcccactgcacaccccca cctccgtatcccacagattgcagcattgtcaggatctggcaagtctga |
Protein Sequence |
>8626 : length: 555 MNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWD FLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSM DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEV VKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFT TVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIR KQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKES LELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQ LINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPP PPYPTDCSIVRIWQV |