Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

90249

Name

UNC5A

Synonym

UNC5H1;unc-5 homolog A (C. elegans);UNC5A;unc-5 homolog A (C. elegans)

Definition

netrin receptor UNC5A|netrin receptor Unc5h1|protein unc-5 homolog 1|protein unc-5 homolog A|unc-5 homolog 1|unc5 (C.elegans homolog) a

Position

5q35.2

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

17504

TUSON P-value

1

Pathways and Diseases

Pathway

Apoptosis;Reactome;REACT:578

Pathway

Axon guidance;KEGG PATHWAY;hsa04360

Pathway

Axon guidance;Reactome;REACT:18266

Pathway

Role of DCC in regulating apoptosis;PID Reactome;500280

Pathway

Netrin-mediated signaling;PID Curated;200074

External Links

Links to Entrez Gene

90249

Links to all GeneRIF Items

90249

Links to iHOP

90249

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>90249 : length: 2529
atggccgtccggcccggcctgtggccagcgctcctgggcatagtcctcgccgcttggctc
cgcggctcgggtgcccagcagagtgccaccgtggccaacccagtgcctggtgccaacccg
gacctgcttccccacttcctggtggagcccgaggatgtgtacatcgtcaagaacaagcca
gtgctgcttgtgtgcaaggccgtgcccgccacgcagatcttcttcaagtgcaacggggag
tgggtgcgccaggtggaccacgtgatcgagcgcagcacagacgggagcagtgggctgccc
accatggaggtccgcattaatgtctcaaggcagcaggtcgagaaggtgttcgggctggag
gaatactggtgccagtgcgtggcatggagctcctcgggcaccaccaagagtcagaaggcc
tacatccgcatagcctatttgcgcaagaacttcgagcaggagccgctggccaaggaggtg
tccctggagcagggcatcgtgctgccctgccgtccaccggagggcatccctccagccgag
gtggagtggctccggaacgaggacctggtggacccgtccctggaccccaatgtatacatc
acgcgggagcacagcctggtggtgcgacaggcccgccttgctgacacggccaactacacc
tgcgtggccaagaacatcgtggcacgtcgccgcagcgcctccgctgctgtcatcgtctac
gtggacggcagctggagcccgtggagcaagtggtcggcctgtgggctggactgcacccac
tggcggagccgtgagtgctctgacccagcaccccgcaacggaggggaggagtgccagggc
actgacctggacacccgcaactgtaccagtgacctctgtgtacacactgcttctggccct
gaggacgtggccctctatgtgggcctcatcgccgtggccgtctgcctggtcctgctgctg
cttgtcctcatcctcgtttattgccggaagaaggaggggctggactcagatgtggctgac
tcgtccattctcacctcaggcttccagcccgtcagcatcaagcccagcaaagcagacaac
ccccatctgctcaccatccagccggacctcagcaccaccaccaccacctaccagggcagt
ctctgtccccggcaggatgggcccagccccaagttccagctcaccaatgggcacctgctc
agccccctgggtggcggccgccacacactgcaccacagctctcccacctctgaggccgag
gagttcgtctcccgcctctccacccagaactacttccgctccctgccccgaggcaccagc
aacatgacctatgggaccttcaacttcctcgggggccggctgatgatccctaatacagga
atcagcctcctcatccccccagatgccataccccgagggaagatctatgagatctacctc
acgctgcacaagccggaagacgtgaggttgcccctagctggctgtcagaccctgctgagt
cccatcgttagctgtggaccccctggcgtcctgctcacccggccagtcatcctggctatg
gaccactgtggggagcccagccctgacagctggagcctgcgcctcaaaaagcagtcgtgc
gagggcagctgggaggatgtgctgcacctgggcgaggaggcgccctcccacctctactac
tgccagctggaggccagtgcctgctacgtcttcaccgagcagctgggccgctttgccctg
gtgggagaggccctcagcgtggctgccgccaagcgcctcaagctgcttctgtttgcgccg
gtggcctgcacctccctcgagtacaacatccgggtctactgcctgcatgacacccacgat
gcactcaaggaggtggtgcagctggagaagcagctggggggacagctgatccaggagcca
cgggtcctgcacttcaaggacagttaccacaacctgcgcctatccatccacgatgtgccc
agctccctgtggaagagtaagctccttgtcagctaccaggagatccccttttatcacatc
tggaatggcacgcagcggtacttgcactgcaccttcaccctggagcgtgtcagccccagc
actagtgacctggcctgcaagctgtgggtgtggcaggtggagggcgacgggcagagcttc
agcatcaacttcaacatcaccaaggacacaaggtttgctgagctgctggctctggagagt
gaagcgggggtcccagccctggtgggccccagtgccttcaagatccccttcctcattcgg
cagaagataatttccagcctggacccaccctgtaggcggggtgccgactggcggactctg
gcccagaaactccacctggacagccatctcagcttctttgcctccaagcccagccccaca
gccatgatcctcaacctgtgggaggcgcggcacttccccaacggcaacctcagccagctg
gctgcagcagtggctggactgggccagccagacgctggcctcttcacagtgtcggaggct
gagtgctga

Protein Sequence

>90249 : length: 842
MAVRPGLWPALLGIVLAAWLRGSGAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKP
VLLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLPTMEVRINVSRQQVEKVFGLE
EYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAE
VEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVY
VDGSWSPWSKWSACGLDCTHWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLCVHTASGP
EDVALYVGLIAVAVCLVLLLLVLILVYCRKKEGLDSDVADSSILTSGFQPVSIKPSKADN
PHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLTNGHLLSPLGGGRHTLHHSSPTSEAE
EFVSRLSTQNYFRSLPRGTSNMTYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYL
TLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLRLKKQSC
EGSWEDVLHLGEEAPSHLYYCQLEASACYVFTEQLGRFALVGEALSVAAAKRLKLLLFAP
VACTSLEYNIRVYCLHDTHDALKEVVQLEKQLGGQLIQEPRVLHFKDSYHNLRLSIHDVP
SSLWKSKLLVSYQEIPFYHIWNGTQRYLHCTFTLERVSPSTSDLACKLWVWQVEGDGQSF
SINFNITKDTRFAELLALESEAGVPALVGPSAFKIPFLIRQKIISSLDPPCRRGADWRTL
AQKLHLDSHLSFFASKPSPTAMILNLWEARHFPNGNLSQLAAAVAGLGQPDAGLFTVSEA
EC



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