| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 9901 |
Name | SRGAP3 |
Synonym | ARHGAP14|MEGAP|SRGAP2|WRP;SLIT-ROBO Rho GTPase activating protein 3;SRGAP3;SLIT-ROBO Rho GTPase activating protein 3 |
Definition | SLIT-ROBO Rho GTPase activating protein 2|SLIT-ROBO Rho GTPase-activating protein 3|WAVE-associated Rac GTPase activating protein|mental disorder-associated GAP|rho GTPase-activating protein 14 |
Position | 3p25.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 15750 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Disease | Mental retardation;FunDO |
Disease | smoking cessation;GAD |
Disease | CHEMDEPENDENCY;GAD |
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External Links |
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Links to Entrez Gene | 9901 |
Links to all GeneRIF Items | 9901 |
Links to iHOP | 9901 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>9901 : length: 3228 atgtcatctcaaactaagttcaagaaagacaaagagatcattgctgaatatgaagcccaa ataaaagagatccgcacgcagctggtggagcagttcaaatgtctggagcagcaatcagag tcgcgactgcagctgcttcaagacctccaggagtttttccgccggaaagctgagattgag ctcgagtactcccgcagcctggagaagctggctgagcgcttctcctccaaaatccgcagc tcccgggagcaccagttcaagaaggaccagtacctcctctcgcctgtgaactgttggtat ctggttctgcatcagacccggcgggagagccgagaccatgccaccctcaatgacatcttc atgaacaatgtcatcgtccgcctctcccagatcagtgaggatgtcatcagactcttcaaa aagagcaaggagattggcctgcagatgcacgaggagctcctgaaggtgaccaatgagctc tacacagtcatgaaaacctaccacatgtaccatgcagagagcatcagtgcggaaagcaag ctgaaggaggctgagaagcaggaggagaagcagttcaataagtcaggagacctcagcatg aacctgctccggcacgaggaccggccccagcgccgcagctctgtgaagaagattgagaag atgaaggagaagaggcaggccaagtactctgagaacaagctgaaatgcacaaaggcccgg aatgactacttgctcaatctggcagccaccaacgcagctataagcaaatactacatccat gatgtctctgatctgatcgattgctgtgatttgggcttccatgccagcctggcccgcacc ttccggacctatctctcagctgaatacaacctggagacctctcgccacgaagggctggat gtcattgagaatgcagtggacaacctggattcccgaagtgacaagcacacagtcatggac atgtgcaatcaagtcttctgccctccactcaagttcgagttccagccccacatgggggat gaggtctgccaggtcagcgctcagcagcccgtccagacagaactgctcatgcgttatcac cagctgcagtccagactggccaccctcaagatagagaatgaggaggttaggaaaaccctg gatgccaccatgcagacattacaggacatgctgactgtggaggactttgatgtctccgat gccttccaacacagtcgatcgacagagtccgtcaagtcggctgcctctgagacctacatg agcaagatcaacattgccaagaggagagccaaccagcaggaaacagaaatgttttatttt acaaaatttaaagagtatgtgaatggcagtaacctcatcaccaagctgcaggccaagcac gatttactcaagcagaccctgggcgaaggggaaagagcagaatgcggcaccaccagagga agaagaaatgctcgaaccaggaaccaggattcaggacaagctataccgcttgtagtcgag agctgcatccgttacatcaatttatatggactccagcagcaggggatcttcagagtgcca ggatctcaggtggaagtcaatgacatcaaaaattcctttgagagaggtgaagaccccctt gtggacgatcaaaatgaacgagatatcaattcagtcgctggtgttttaaaactgtatttc cgaggactggaaaacccactctttcctaaggaaaggtttcaagatttgatatctactatt aaactggagaacccagccgagagggtgcaccagatccaacaaatcctcgtcacccttccc cgcgtggtcattgtggtcatgagatacctcttcgctttcctcaaccacctctcccagtat agcgacgagaacatgatggatccctacaacctggccatctgcttcgggcctaccctcatg cacatccctgatgggcaggaccctgtgtcctgccaggcacacatcaatgaagtcatcaaa accatcatcatccatcatgaagccatcttccccagcccccgggagctagagggacctgtg tatgaaaaatgcatggctggaggggaagaatattgtgacagcccacacagcgagccaggg gccatcgatgaagttgaccatgacaatggcactgagcctcataccagcgatgaagaagtg gagcagatcgaggctattgccaagtttgactacatggggcggtccccgcgtgagctatcc ttcaagaagggggcctcgctgctcctgtaccaccgcgcctcggaggactggtgggagggc cggcacaacggcgtggatggactcatcccccatcagtacatagttgtacaggacatggat gatgccttctccgacagcctgagccagaaggctgacagcgaggccagcagtgggccattg ctggatgacaaggcctcttccaaaaacgacctccagtcccccacggagcacatctcggat tacggctttgggggggtgatgggccgagtgcggttacgatctgatggagcagccatcccc agacgccgaagcgggggcgacacacacagcccgccccggggcctgggccccagcatagac acaccaccccgggctgctgcctgccccagcagcccccacaaaatccccctcacccggggg aggatcgagagccctgagaagcggaggatggcgacgttcgggagcgctggcagcatcaac taccctgacaagaaggcgctctccgaagggcactcgatgaggtcgacctgcggttccacc aggcacagcagcctaggggaccacaagtccctggaggccgaggccctggcagaagacatc gagaagaccatgagcacggctctgcacgagttgcgggaactcgagaggcagaacacggtc aagcaggcgccagatgtggtgctggacaccctggagcccctgaagaacccgccaggcccc gtcagctcggagcccgccagtccccttcacaccatcgtcatccgcgaccccgatgccgcc atgcgccgcagcagcagctcctccaccgagatgatgaccaccttcaagccagccctgtcc gcccgcctggctggcgcccagctccgcccgccccccatgcggcccgtgcggccggtggtc cagcaccggtccagcagcagcagcagctcgggcgtgggcagcccggccgtgacgcccacc gagaagatgttccccaacagctcagcggacaagtcgggcaccatgtga |
Protein Sequence |
>9901 : length: 1075 MSSQTKFKKDKEIIAEYEAQIKEIRTQLVEQFKCLEQQSESRLQLLQDLQEFFRRKAEIE LEYSRSLEKLAERFSSKIRSSREHQFKKDQYLLSPVNCWYLVLHQTRRESRDHATLNDIF MNNVIVRLSQISEDVIRLFKKSKEIGLQMHEELLKVTNELYTVMKTYHMYHAESISAESK LKEAEKQEEKQFNKSGDLSMNLLRHEDRPQRRSSVKKIEKMKEKRQAKYSENKLKCTKAR NDYLLNLAATNAAISKYYIHDVSDLIDCCDLGFHASLARTFRTYLSAEYNLETSRHEGLD VIENAVDNLDSRSDKHTVMDMCNQVFCPPLKFEFQPHMGDEVCQVSAQQPVQTELLMRYH QLQSRLATLKIENEEVRKTLDATMQTLQDMLTVEDFDVSDAFQHSRSTESVKSAASETYM SKINIAKRRANQQETEMFYFTKFKEYVNGSNLITKLQAKHDLLKQTLGEGERAECGTTRG RRNARTRNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPL VDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLP RVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIK TIIIHHEAIFPSPRELEGPVYEKCMAGGEEYCDSPHSEPGAIDEVDHDNGTEPHTSDEEV EQIEAIAKFDYMGRSPRELSFKKGASLLLYHRASEDWWEGRHNGVDGLIPHQYIVVQDMD DAFSDSLSQKADSEASSGPLLDDKASSKNDLQSPTEHISDYGFGGVMGRVRLRSDGAAIP RRRSGGDTHSPPRGLGPSIDTPPRAAACPSSPHKIPLTRGRIESPEKRRMATFGSAGSIN YPDKKALSEGHSMRSTCGSTRHSSLGDHKSLEAEALAEDIEKTMSTALHELRELERQNTV KQAPDVVLDTLEPLKNPPGPVSSEPASPLHTIVIRDPDAAMRRSSSSSTEMMTTFKPALS ARLAGAQLRPPPMRPVRPVVQHRSSSSSSSGVGSPAVTPTEKMFPNSSADKSGTM |