General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 23365 |
Name | ARHGEF12 |
Synonymous | LARG|PRO2792;Rho guanine nucleotide exchange factor (GEF) 12;ARHGEF12;Rho guanine nucleotide exchange factor (GEF) 12 |
Definition | leukemia-associated RhoGEF|leukemia-associated rho guanine nucleotide exchange factor|rho guanine nucleotide exchange factor 12 |
Position | 11q23.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
IGF1R | IMID; |
interacts with |
ABCA1 | HPRD; |
interacts with |
CD44 | HPRD; |
interacts with |
CUL3 | BIOGRID; |
interacts with |
GNA12 | BIOGRID; |
interacts with |
GNA13 | BIOGRID; |
interacts with |
GNA13 | HPRD; |
interacts with |
IGF1R | BIOGRID; |
interacts with |
IGF1R | HPRD; |
interacts with |
IGF1R | MINT; |
interacts with |
LPAR1 | HPRD; |
interacts with |
Lpar1 | MINT; |
interacts with |
LPAR2 | HPRD; |
interacts with |
Lpar2 | MINT; |
interacts with |
PLXNB1 | BIOGRID; |
interacts with |
PLXNB1 | HPRD; |
interacts with |
PLXNB2 | BIOGRID; |
interacts with |
PLXNB2 | HPRD; |
interacts with |
RHOA | BIOGRID; |
interacts with |
RHOA | HPRD; |
interacts with |
RHOA | MINT; |
interacts with |
TEC | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
sequential catalysis |
ARHGEF12 | IMID; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ARHGEF12 | IMID; |
reacts with |
IGF1R | IMID; |