General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 2810 |
Name | SFN |
Synonymous | YWHAS;stratifin;SFN;stratifin |
Definition | 14-3-3 protein sigma|14-3-3 sigma|epithelial cell marker protein 1 |
Position | 1p36.11 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
FKBP5 | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
interacts with |
ABLIM1 | BIOGRID; |
interacts with |
ABLIM1 | MINT; |
interacts with |
ACTA2 | MINT; |
interacts with |
ACTB | MINT; |
interacts with |
AKT1 | MINT; |
interacts with |
ANKRD18A | MINT; |
interacts with |
ANKS1A | BIOGRID; |
interacts with |
ANKS1A | MINT; |
interacts with |
ANPEP | MINT; |
interacts with |
APC | BIOGRID; |
interacts with |
APC | MINT; |
interacts with |
APLP2 | BIOGRID; |
interacts with |
ARAF | BIOGRID; |
interacts with |
ARAF | MINT; |
interacts with |
ARHGAP11A | BIOGRID; |
interacts with |
ARHGAP11A | MINT; |
interacts with |
ARHGAP21 | BIOGRID; |
interacts with |
ARHGAP21 | MINT; |
interacts with |
ARHGAP32 | BIOGRID; |
interacts with |
ARHGAP32 | MINT; |
interacts with |
ARHGEF16 | BIOGRID; |
interacts with |
ARHGEF16 | MINT; |
interacts with |
ARHGEF17 | BIOGRID; |
interacts with |
ARHGEF17 | MINT; |
interacts with |
ARHGEF5 | BIOGRID; |
interacts with |
ARHGEF5 | MINT; |
interacts with |
ASAP1 | INTACT; |
interacts with |
ATP5A1 | MINT; |
interacts with |
ATP5B | MINT; |
interacts with |
BAD | BIOGRID; |
interacts with |
Bad | MINT; |
interacts with |
BAD | MINT; |
interacts with |
BAX | HPRD; |
interacts with |
BAX | MINT; |
interacts with |
BCAR1 | BIOGRID; |
interacts with |
BCAR1 | MINT; |
interacts with |
BMI1 | INTACT; |
interacts with |
C1orf106 | MINT; |
interacts with |
CBL | MINT; |
interacts with |
CCAR1 | HPRD; |
interacts with |
CCDC101 | MINT; |
interacts with |
CCDC158 | INTACT; |
interacts with |
CDC25B | HPRD; |
interacts with |
CDC25B | MINT; |
interacts with |
CDC42BPG | MINT; |
interacts with |
CDK1 | BIOGRID; |
interacts with |
CDK1 | MINT; |
interacts with |
CENPF | INTACT; |
interacts with |
CGN | BIOGRID; |
interacts with |
CGN | MINT; |
interacts with |
CHD7 | INTACT; |
interacts with |
CHEK1 | BIOGRID; |
interacts with |
CHST1 | BIOGRID; |
interacts with |
CHST1 | HPRD; |
interacts with |
CHST1 | MINT; |
interacts with |
CPS1 | MINT; |
interacts with |
CSNK2A1 | BIOGRID; |
interacts with |
CSNK2A1 | INTACT; |
interacts with |
CSNK2A1 | MINT; |
interacts with |
CSNK2A2 | INTACT; |
interacts with |
CSNK2B | INTACT; |
interacts with |
CYTH2 | BIOGRID; |
interacts with |
CYTH2 | MINT; |
interacts with |
DCAF7 | BIOGRID; |
interacts with |
DCAF7 | MINT; |
interacts with |
DTX2 | BIOGRID; |
interacts with |
DTX2 | MINT; |
interacts with |
DYRK1A | BIOGRID; |
interacts with |
DYRK1A | MINT; |
interacts with |
EDC3 | MINT; |
interacts with |
EEF1A1 | HPRD; |
interacts with |
EEF1A1 | MINT; |
interacts with |
EGFR | HPRD; |
interacts with |
EGFR | MINT; |
interacts with |
EIF2S1 | HPRD; |
interacts with |
EIF4B | HPRD; |
interacts with |
ERCC6 | INTACT; |
interacts with |
ERRFI1 | BIOGRID; |
interacts with |
ERRFI1 | MINT; |
interacts with |
FAM117B | MINT; |
interacts with |
FAM189A2 | BIOGRID; |
interacts with |
FAM189A2 | HPRD; |
interacts with |
FAM53B | MINT; |
interacts with |
FER | INTACT; |
interacts with |
GAB2 | MINT; |
interacts with |
GAN | BIOGRID; |
interacts with |
GAN | MINT; |
interacts with |
GPRIN2 | BIOGRID; |
interacts with |
GPRIN2 | HPRD; |
interacts with |
GPRIN2 | MINT; |
interacts with |
GRB7 | BIOGRID; |
interacts with |
GRB7 | MINT; |
interacts with |
H1F0 | MINT; |
interacts with |
HDAC4 | BIOGRID; |
interacts with |
HDAC4 | MINT; |
interacts with |
HDAC5 | HPRD; |
interacts with |
HDAC5 | MINT; |
interacts with |
HDAC7 | BIOGRID; |
interacts with |
HDAC7 | MINT; |
interacts with |
HDAC9 | BIOGRID; |
interacts with |
HIST1H1A | INTACT; |
interacts with |
HIST1H2BD | MINT; |
interacts with |
HMGCS2 | MINT; |
interacts with |
HNRNPD | HPRD; |
interacts with |
HNRNPU | BIOGRID; |
interacts with |
HNRNPU | MINT; |
interacts with |
HSPB1 | MINT; |
interacts with |
ILDR2 | MINT; |
interacts with |
ING1 | BIOGRID; |
interacts with |
ING1 | HPRD; |
interacts with |
ING1 | MINT; |
interacts with |
IRS1 | BIOGRID; |
interacts with |
IRS1 | MINT; |
interacts with |
IRS2 | BIOGRID; |
interacts with |
IRS2 | MINT; |
interacts with |
ISCU | BIOGRID; |
interacts with |
ISCU | MINT; |
interacts with |
ITCH | BIOGRID; |
interacts with |
JUB | BIOGRID; |
interacts with |
JUB | MINT; |
interacts with |
KCNK15 | HPRD; |
interacts with |
KCNK3 | HPRD; |
interacts with |
KCNK9 | HPRD; |
interacts with |
KHDRBS2 | INTACT; |
interacts with |
KIAA0408 | BIOGRID; |
interacts with |
KIAA0408 | HPRD; |
interacts with |
KIAA0408 | MINT; |
interacts with |
KIAA0930 | MINT; |
interacts with |
KIF23 | BIOGRID; |
interacts with |
KIF23 | MINT; |
interacts with |
KIF5B | BIOGRID; |
interacts with |
KIF5B | MINT; |
interacts with |
KLC1 | BIOGRID; |
interacts with |
KLC1 | MINT; |
interacts with |
KLC2 | BIOGRID; |
interacts with |
KLC2 | MINT; |
interacts with |
KLHDC2 | BIOGRID; |
interacts with |
KLHDC2 | MINT; |
interacts with |
KRT17 | MINT; |
interacts with |
KRT8 | MINT; |
interacts with |
LAD1 | BIOGRID; |
interacts with |
LAD1 | MINT; |
interacts with |
LMO7 | BIOGRID; |
interacts with |
LMO7 | MINT; |
interacts with |
LSR | BIOGRID; |
interacts with |
MAGI1 | BIOGRID; |
interacts with |
MAGI1 | MINT; |
interacts with |
MAP3K2 | BIOGRID; |
interacts with |
MAP3K2 | MINT; |
interacts with |
MAP3K5 | HPRD; |
interacts with |
MAPKAP1 | BIOGRID; |
interacts with |
MAPKAP1 | MINT; |
interacts with |
MARK1 | BIOGRID; |
interacts with |
MARK1 | MINT; |
interacts with |
MARK2 | BIOGRID; |
interacts with |
MARK2 | MINT; |
interacts with |
MARK3 | BIOGRID; |
interacts with |
MARK3 | HPRD; |
interacts with |
MARK3 | MINT; |
interacts with |
MDM1 | INTACT; |
interacts with |
MDM2 | BIOGRID; |
interacts with |
MDM2 | MINT; |
interacts with |
MDM4 | BIOGRID; |
interacts with |
MDM4 | HPRD; |
interacts with |
MDM4 | MINT; |
interacts with |
MKI67 | INTACT; |
interacts with |
MLTK | BIOGRID; |
interacts with |
MLTK | MINT; |
interacts with |
MOV10 | INTACT; |
interacts with |
MPRIP | BIOGRID; |
interacts with |
MPRIP | MINT; |
interacts with |
MST1R | CELL_MAP; |
interacts with |
MST1R | HPRD; |
interacts with |
MYCBP2 | BIOGRID; |
interacts with |
MYCBP2 | MINT; |
interacts with |
MYH13 | MINT; |
interacts with |
MYH7 | MINT; |
interacts with |
MYH9 | MINT; |
interacts with |
MYL3 | MINT; |
interacts with |
MYLK2 | MINT; |
interacts with |
NEDD4L | BIOGRID; |
interacts with |
NR3C1 | BIOGRID; |
interacts with |
NR3C1 | HPRD; |
interacts with |
NR3C1 | MINT; |
interacts with |
OSBPL3 | BIOGRID; |
interacts with |
OSBPL3 | MINT; |
interacts with |
PACS2 | MINT; |
interacts with |
PAK4 | BIOGRID; |
interacts with |
PAK4 | MINT; |
interacts with |
PARD3B | BIOGRID; |
interacts with |
PARD3B | MINT; |
interacts with |
PCGF2 | INTACT; |
interacts with |
PCGF6 | INTACT; |
interacts with |
PDZD11 | MINT; |
interacts with |
PHC1 | INTACT; |
interacts with |
PHC2 | INTACT; |
interacts with |
PHC3 | INTACT; |
interacts with |
PI4KB | BIOGRID; |
interacts with |
PI4KB | MINT; |
interacts with |
PIK3C2B | BIOGRID; |
interacts with |
PIK3C2B | MINT; |
interacts with |
PKHD1 | BIOGRID; |
interacts with |
PKP2 | BIOGRID; |
interacts with |
PKP2 | MINT; |
interacts with |
PKP3 | BIOGRID; |
interacts with |
PKP3 | MINT; |
interacts with |
PLEKHF2 | BIOGRID; |
interacts with |
PLEKHF2 | HPRD; |
interacts with |
PLEKHF2 | MINT; |
interacts with |
PLK4 | BIOGRID; |
interacts with |
PLK4 | HPRD; |
interacts with |
PLK4 | MINT; |
interacts with |
PPFIBP1 | BIOGRID; |
interacts with |
PPFIBP1 | MINT; |
interacts with |
PPFIBP2 | BIOGRID; |
interacts with |
PPFIBP2 | MINT; |
interacts with |
PPP1R3D | BIOGRID; |
interacts with |
PPP1R3D | MINT; |
interacts with |
PRKAR2A | MINT; |
interacts with |
PRKDC | MINT; |
interacts with |
PTOV1 | BIOGRID; |
interacts with |
PTOV1 | MINT; |
interacts with |
PTPN2 | BIOGRID; |
interacts with |
PTPN2 | MINT; |
interacts with |
PTPN3 | BIOGRID; |
interacts with |
PTPN3 | MINT; |
interacts with |
RACGAP1 | BIOGRID; |
interacts with |
RACGAP1 | MINT; |
interacts with |
RAE1 | BIOGRID; |
interacts with |
RAE1 | MINT; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | MINT; |
interacts with |
RALGPS2 | BIOGRID; |
interacts with |
RALGPS2 | MINT; |
interacts with |
RASSF1 | MINT; |
interacts with |
REEP3 | MINT; |
interacts with |
REEP4 | MINT; |
interacts with |
RFFL | HPRD; |
interacts with |
RHPN2 | BIOGRID; |
interacts with |
RHPN2 | MINT; |
interacts with |
RICTOR | MINT; |
interacts with |
RING1 | INTACT; |
interacts with |
RNF17 | INTACT; |
interacts with |
RNF2 | INTACT; |
interacts with |
RUVBL2 | INTACT; |
interacts with |
SAMD4A | MINT; |
interacts with |
SAMSN1 | BIOGRID; |
interacts with |
SASH1 | BIOGRID; |
interacts with |
SASH1 | MINT; |
interacts with |
SAV1 | BIOGRID; |
interacts with |
SAV1 | MINT; |
interacts with |
SCEL | MINT; |
interacts with |
SGK223 | MINT; |
interacts with |
SH2D3A | BIOGRID; |
interacts with |
SH2D3A | MINT; |
interacts with |
SH3BP4 | BIOGRID; |
interacts with |
SH3BP4 | MINT; |
interacts with |
SHCBP1 | BIOGRID; |
interacts with |
SHCBP1 | MINT; |
interacts with |
SHROOM1 | MINT; |
interacts with |
SHROOM3 | BIOGRID; |
interacts with |
SHROOM3 | MINT; |
interacts with |
SIPA1L1 | BIOGRID; |
interacts with |
SIPA1L1 | MINT; |
interacts with |
SIPA1L3 | BIOGRID; |
interacts with |
SIPA1L3 | MINT; |
interacts with |
SLC25A5 | INTACT; |
interacts with |
SMC3 | INTACT; |
interacts with |
SMG1 | INTACT; |
interacts with |
SORBS2 | BIOGRID; |
interacts with |
SORBS2 | MINT; |
interacts with |
SPIRE1 | BIOGRID; |
interacts with |
SPIRE1 | MINT; |
interacts with |
SRRM2 | BIOGRID; |
interacts with |
SRRM2 | MINT; |
interacts with |
SRSF10 | BIOGRID; |
interacts with |
SRSF10 | MINT; |
interacts with |
SSX10 | INTACT; |
interacts with |
ST5 | BIOGRID; |
interacts with |
ST5 | MINT; |
interacts with |
STAMBPL1 | INTACT; |
interacts with |
SYNJ2 | BIOGRID; |
interacts with |
SYNJ2 | MINT; |
interacts with |
TBL3 | BIOGRID; |
interacts with |
TBL3 | HPRD; |
interacts with |
TBL3 | MINT; |
interacts with |
TJP2 | BIOGRID; |
interacts with |
TJP2 | MINT; |
interacts with |
TNK1 | BIOGRID; |
interacts with |
TNK1 | MINT; |
interacts with |
TNS4 | BIOGRID; |
interacts with |
TNS4 | MINT; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TP53 | MINT; |
interacts with |
TPD52L1 | MINT; |
interacts with |
TRIM25 | BIOGRID; |
interacts with |
TRIM25 | HPRD; |
interacts with |
TRIM32 | BIOGRID; |
interacts with |
TRIM32 | MINT; |
interacts with |
TSC2 | HPRD; |
interacts with |
TSC2 | MINT; |
interacts with |
TUBA1C | MINT; |
interacts with |
TUT1 | MINT; |
interacts with |
USP43 | MINT; |
interacts with |
USP8 | BIOGRID; |
interacts with |
USP8 | MINT; |
interacts with |
WDHD1 | INTACT; |
interacts with |
WDR37 | MINT; |
interacts with |
WDYHV1 | BIOGRID; |
interacts with |
WDYHV1 | HPRD; |
interacts with |
WDYHV1 | MINT; |
interacts with |
WEE1 | BIOGRID; |
interacts with |
WEE1 | MINT; |
interacts with |
WNK4 | MINT; |
interacts with |
YWHAB | INTACT; |
interacts with |
YWHAB | MINT; |
interacts with |
YWHAE | INTACT; |
interacts with |
YWHAE | MINT; |
interacts with |
YWHAG | BIOGRID; |
interacts with |
YWHAG | HPRD; |
interacts with |
YWHAG | INTACT; |
interacts with |
YWHAG | MINT; |
interacts with |
YWHAH | INTACT; |
interacts with |
YWHAH | MINT; |
interacts with |
YWHAQ | INTACT; |
interacts with |
YWHAQ | MINT; |
interacts with |
YWHAZ | INTACT; |
interacts with |
YWHAZ | MINT; |
interacts with |
ZFP36 | HPRD; |
interacts with |
ZNF546 | INTACT; |
interacts with |
ZNF638 | BIOGRID; |
interacts with |
ZNF638 | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
TP53 | NCI_NATURE; |
metabolic catalysis |
ZNF385A | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
FKBP5 | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
SFN | NCI_NATURE; |