General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 3690 |
Name | ITGB3 |
Synonymous | BDPLT16|BDPLT2|CD61|GP3A|GPIIIa|GT;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);ITGB3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
Definition | integrin beta-3|platelet membrane glycoprotein IIIa |
Position | 17q21.32 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
ANGPTL3 | NCI_NATURE; |
in same component |
APBB1IP | REACTOME; |
in same component |
BCAR1 | NCI_NATURE; |
in same component |
BCAR1 | REACTOME; |
in same component |
CBL | NCI_NATURE; |
in same component |
CD47 | NCI_NATURE; |
in same component |
COL1A1 | NCI_NATURE; |
in same component |
COL1A2 | NCI_NATURE; |
in same component |
COL4A3 | NCI_NATURE; |
in same component |
CSF1R | NCI_NATURE; |
in same component |
CSK | REACTOME; |
in same component |
CYR61 | NCI_NATURE; |
in same component |
EDIL3 | NCI_NATURE; |
in same component |
F11R | NCI_NATURE; |
in same component |
FBN1 | NCI_NATURE; |
in same component |
FBN1 | REACTOME; |
in same component |
FGA | NCI_NATURE; |
in same component |
FGA | REACTOME; |
in same component |
FGB | NCI_NATURE; |
in same component |
FGB | REACTOME; |
in same component |
FGG | NCI_NATURE; |
in same component |
FGG | REACTOME; |
in same component |
FN1 | NCI_NATURE; |
in same component |
FN1 | REACTOME; |
in same component |
GIT1 | NCI_NATURE; |
in same component |
GPR124 | NCI_NATURE; |
in same component |
HMGB1 | NCI_NATURE; |
in same component |
HSP90AA1 | NCI_NATURE; |
in same component |
IBSP | NCI_NATURE; |
in same component |
IBSP | REACTOME; |
in same component |
ITGA2B | NCI_NATURE; |
in same component |
ITGA2B | REACTOME; |
in same component |
ITGAV | NCI_NATURE; |
in same component |
ITGAV | REACTOME; |
in same component |
KDR | NCI_NATURE; |
in same component |
L1CAM | NCI_NATURE; |
in same component |
LAMA4 | NCI_NATURE; |
in same component |
LAMB1 | NCI_NATURE; |
in same component |
LAMC1 | NCI_NATURE; |
in same component |
MFGE8 | NCI_NATURE; |
in same component |
NCL | NCI_NATURE; |
in same component |
PDGFB | NCI_NATURE; |
in same component |
PDGFRB | NCI_NATURE; |
in same component |
PECAM1 | NCI_NATURE; |
in same component |
PECAM1 | REACTOME; |
in same component |
PLAU | NCI_NATURE; |
in same component |
PLAUR | NCI_NATURE; |
in same component |
PTK2B | NCI_NATURE; |
in same component |
PTK2 | REACTOME; |
in same component |
PVR | NCI_NATURE; |
in same component |
PXN | NCI_NATURE; |
in same component |
RHOA | NCI_NATURE; |
in same component |
ROCK1 | NCI_NATURE; |
in same component |
SDC1 | NCI_NATURE; |
in same component |
SDC4 | NCI_NATURE; |
in same component |
SERPINE1 | NCI_NATURE; |
in same component |
SHC1 | REACTOME; |
in same component |
SOS1 | REACTOME; |
in same component |
SPHK1 | NCI_NATURE; |
in same component |
SPP1 | NCI_NATURE; |
in same component |
SYK | REACTOME; |
in same component |
TGFBI | NCI_NATURE; |
in same component |
TGFBR2 | NCI_NATURE; |
in same component |
THBS1 | NCI_NATURE; |
in same component |
THBS1 | REACTOME; |
in same component |
THY1 | NCI_NATURE; |
in same component |
TLN1 | NCI_NATURE; |
in same component |
TLN1 | REACTOME; |
in same component |
TNC | REACTOME; |
in same component |
VEGFA | NCI_NATURE; |
in same component |
VTN | NCI_NATURE; |
in same component |
VTN | REACTOME; |
interacts with |
ADAM15 | HPRD; |
interacts with |
ADAM23 | HPRD; |
interacts with |
AKT1 | HPRD; |
interacts with |
ANGPTL3 | HPRD; |
interacts with |
ANKS1B | MINT; |
interacts with |
Apba1 | MINT; |
interacts with |
Apba2 | MINT; |
interacts with |
CAPN1 | HPRD; |
interacts with |
CD36 | BIOGRID; |
interacts with |
CD36 | HPRD; |
interacts with |
CD47 | HPRD; |
interacts with |
CD9 | HPRD; |
interacts with |
CIB1 | BIOGRID; |
interacts with |
CIB1 | HPRD; |
interacts with |
COL1A2 | HPRD; |
interacts with |
COL4A3 | HPRD; |
interacts with |
COL6A3 | HPRD; |
interacts with |
CTSG | HPRD; |
interacts with |
DAB1 | HPRD; |
interacts with |
Dab1 | MINT; |
interacts with |
DAB2 | HPRD; |
interacts with |
Dab2 | MINT; |
interacts with |
DOK1 | HPRD; |
interacts with |
Dok1 | MINT; |
interacts with |
EPS8 | HPRD; |
interacts with |
EPS8 | MINT; |
interacts with |
F11R | HPRD; |
interacts with |
F2 | HPRD; |
interacts with |
FCER2 | HPRD; |
interacts with |
FGA | HPRD; |
interacts with |
FGG | HPRD; |
interacts with |
FLNA | BIOGRID; |
interacts with |
FLNB | BIOGRID; |
interacts with |
GULP1 | MINT; |
interacts with |
ILK | BIOGRID; |
interacts with |
ILK | HPRD; |
interacts with |
Irs1 | MINT; |
interacts with |
ITGA2B | HPRD; |
interacts with |
ITGA2B | MINT; |
interacts with |
ITGA2 | HPRD; |
interacts with |
ITGA5 | HPRD; |
interacts with |
ITGAV | BIOGRID; |
interacts with |
ITGAV | HPRD; |
interacts with |
ITGAV | MINT; |
interacts with |
ITGB1 | HPRD; |
interacts with |
ITGB3BP | BIOGRID; |
interacts with |
ITGB3BP | HPRD; |
interacts with |
KDR | HPRD; |
interacts with |
LAMA4 | HPRD; |
interacts with |
LYN | MINT; |
interacts with |
MAPK8IP1 | MINT; |
interacts with |
NID1 | HPRD; |
interacts with |
NOV | HPRD; |
interacts with |
NUMB | HPRD; |
interacts with |
Numb | MINT; |
interacts with |
P2RY2 | HPRD; |
interacts with |
PDGFRA | BIOGRID; |
interacts with |
PDGFRA | HPRD; |
interacts with |
PDGFRB | BIOGRID; |
interacts with |
PDGFRB | HPRD; |
interacts with |
PDPK1 | HPRD; |
interacts with |
PECAM1 | BIOGRID; |
interacts with |
PECAM1 | HPRD; |
interacts with |
PPAP2B | HPRD; |
interacts with |
PTK2B | BIOGRID; |
interacts with |
PTK2B | HPRD; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PTPN11 | MINT; |
interacts with |
PTPN1 | MINT; |
interacts with |
PXN | BIOGRID; |
interacts with |
PXN | HPRD; |
interacts with |
RABGAP1 | MINT; |
interacts with |
RAC1 | NCI_NATURE; |
interacts with |
RGS12 | MINT; |
interacts with |
RHOA | NCI_NATURE; |
interacts with |
SHC1 | HPRD; |
interacts with |
Shc3 | MINT; |
interacts with |
SPP1 | HPRD; |
interacts with |
SRC | HPRD; |
interacts with |
Src | MINT; |
interacts with |
SRC | MINT; |
interacts with |
TENC1 | HPRD; |
interacts with |
TENC1 | MINT; |
interacts with |
TGM2 | HPRD; |
interacts with |
THBS1 | BIOGRID; |
interacts with |
THBS1 | HPRD; |
interacts with |
TLN1 | BIOGRID; |
interacts with |
TLN1 | HPRD; |
interacts with |
Tln1 | MINT; |
interacts with |
TLN1 | MINT; |
interacts with |
UBQLN1 | HPRD; |
interacts with |
VCL | NCI_NATURE; |
interacts with |
VTN | HPRD; |
interacts with |
YES1 | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
STAT6 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
ANGPTL3 | NCI_NATURE; |
reacts with |
APBB1IP | REACTOME; |
reacts with |
BCAR1 | NCI_NATURE; |
reacts with |
BCAR1 | REACTOME; |
reacts with |
CASP8 | NCI_NATURE; |
reacts with |
CBL | NCI_NATURE; |
reacts with |
CD47 | NCI_NATURE; |
reacts with |
COL1A1 | NCI_NATURE; |
reacts with |
COL1A2 | NCI_NATURE; |
reacts with |
COL4A3 | NCI_NATURE; |
reacts with |
CSF1R | NCI_NATURE; |
reacts with |
CSK | REACTOME; |
reacts with |
CYR61 | NCI_NATURE; |
reacts with |
EDIL3 | NCI_NATURE; |
reacts with |
F11R | NCI_NATURE; |
reacts with |
FBN1 | NCI_NATURE; |
reacts with |
FBN1 | REACTOME; |
reacts with |
FGA | NCI_NATURE; |
reacts with |
FGA | REACTOME; |
reacts with |
FGB | NCI_NATURE; |
reacts with |
FGB | REACTOME; |
reacts with |
FGG | NCI_NATURE; |
reacts with |
FGG | REACTOME; |
reacts with |
FN1 | NCI_NATURE; |
reacts with |
FN1 | REACTOME; |
reacts with |
GPR124 | NCI_NATURE; |
reacts with |
HMGB1 | NCI_NATURE; |
reacts with |
HSP90AA1 | NCI_NATURE; |
reacts with |
IBSP | NCI_NATURE; |
reacts with |
IBSP | REACTOME; |
reacts with |
ITGA2B | NCI_NATURE; |
reacts with |
ITGA2B | REACTOME; |
reacts with |
ITGAV | NCI_NATURE; |
reacts with |
ITGAV | REACTOME; |
reacts with |
ITGB3 | NCI_NATURE; |
reacts with |
ITGB3 | REACTOME; |
reacts with |
KDR | NCI_NATURE; |
reacts with |
L1CAM | NCI_NATURE; |
reacts with |
LAMA4 | NCI_NATURE; |
reacts with |
LAMB1 | NCI_NATURE; |
reacts with |
LAMC1 | NCI_NATURE; |
reacts with |
MFGE8 | NCI_NATURE; |
reacts with |
NCL | NCI_NATURE; |
reacts with |
PDGFB | NCI_NATURE; |
reacts with |
PDGFRB | NCI_NATURE; |
reacts with |
PECAM1 | NCI_NATURE; |
reacts with |
PECAM1 | REACTOME; |
reacts with |
PLAU | NCI_NATURE; |
reacts with |
PLAUR | NCI_NATURE; |
reacts with |
PTK2B | NCI_NATURE; |
reacts with |
PTK2 | REACTOME; |
reacts with |
PVR | NCI_NATURE; |
reacts with |
RHOA | NCI_NATURE; |
reacts with |
ROCK1 | NCI_NATURE; |
reacts with |
SDC1 | NCI_NATURE; |
reacts with |
SDC4 | NCI_NATURE; |
reacts with |
SERPINE1 | NCI_NATURE; |
reacts with |
SHC1 | REACTOME; |
reacts with |
SOS1 | REACTOME; |
reacts with |
SPHK1 | NCI_NATURE; |
reacts with |
SPP1 | NCI_NATURE; |
reacts with |
SYK | REACTOME; |
reacts with |
TGFBI | NCI_NATURE; |
reacts with |
TGFBR2 | NCI_NATURE; |
reacts with |
THBS1 | NCI_NATURE; |
reacts with |
THBS1 | REACTOME; |
reacts with |
THY1 | NCI_NATURE; |
reacts with |
TLN1 | NCI_NATURE; |
reacts with |
TLN1 | REACTOME; |
reacts with |
TNC | NCI_NATURE; |
reacts with |
TNC | REACTOME; |
reacts with |
VEGFA | NCI_NATURE; |
reacts with |
VTN | NCI_NATURE; |
reacts with |
VTN | REACTOME; |
state change |
APBB1IP | REACTOME; |
state change |
CSF1 | NCI_NATURE; |
state change |
FGF2 | NCI_NATURE; |
state change |
ITGA2B | REACTOME; |
state change |
ITGB3 | REACTOME; |
state change |
LRP1 | NCI_NATURE; |
state change |
PTK2 | REACTOME; |
state change |
PTPN1 | REACTOME; |
state change |
SYK | REACTOME; |
state change |
TLN1 | REACTOME; |
state change |
VTN | NCI_NATURE; |