Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

675

Name

BRCA2

Synonymous

BRCC2|BROVCA2|FACD|FAD|FAD1|FANCD|FANCD1|GLM3|PNCA2|XRCC11;breast cancer 2, early onset;BRCA2;breast cancer 2, early onset

Definition

BRCA1/BRCA2-containing complex, subunit 2|Fanconi anemia group D1 protein|breast and ovarian cancer susceptibility gene, early onset|breast cancer 2 tumor suppressor|breast cancer type 2 susceptibility protein

Position

13q12.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 ATMREACTOME;

in same component

 BLMREACTOME;

in same component

 BRCA1REACTOME;

in same component

 CDK4REACTOME;

in same component

 DMC1REACTOME;

in same component

 FANCD2NCI_NATURE;

in same component

 FANCGNCI_NATURE;

in same component

 FANCINCI_NATURE;

in same component

 H2AFXREACTOME;

in same component

 HIST3H3REACTOME;

in same component

 MSH4REACTOME;

in same component

 MSH5REACTOME;

in same component

 PALB2NCI_NATURE;

in same component

 PALB2REACTOME;

in same component

 RAD51NCI_NATURE;

in same component

 RAD51REACTOME;

in same component

 RPA1REACTOME;

in same component

 RPA2REACTOME;

in same component

 RPA3REACTOME;

in same component

 TOP3AREACTOME;

in same component

 XRCC3NCI_NATURE;

interacts with

 ABL1MINT;

interacts with

 ATMBIOGRID;

interacts with

 ATRBIOGRID;

interacts with

 AURKBBIOGRID;

interacts with

 AURKBHPRD;

interacts with

 BACH1BIOGRID;

interacts with

 BARD1BIOGRID;

interacts with

 BARD1HPRD;

interacts with

 BCCIPBIOGRID;

interacts with

 BCCIPHPRD;

interacts with

 BRCA1BIOGRID;

interacts with

 BRCC3BIOGRID;

interacts with

 BREBIOGRID;

interacts with

 BUB1BBIOGRID;

interacts with

 BUB1BHPRD;

interacts with

 CCNA2HPRD;

interacts with

 CCNE1HPRD;

interacts with

 CDK2HPRD;

interacts with

 CHEK2BIOGRID;

interacts with

 DMC1MINT;

interacts with

 EMSYBIOGRID;

interacts with

 EMSYHPRD;

interacts with

 FANCD2BIOGRID;

interacts with

 FANCD2HPRD;

interacts with

 FANCEBIOGRID;

interacts with

 FANCEHPRD;

interacts with

 FANCGBIOGRID;

interacts with

 FLNABIOGRID;

interacts with

 FLNAHPRD;

interacts with

 FYNMINT;

interacts with

 H2AFXBIOGRID;

interacts with

 HMG20BBIOGRID;

interacts with

 HMG20BHPRD;

interacts with

 HMG20BINTACT;

interacts with

 KAT2BBIOGRID;

interacts with

 KAT2BHPRD;

interacts with

 KIF4ABIOGRID;

interacts with

 MCPH1BIOGRID;

interacts with

 MORF4L1BIOGRID;

interacts with

 PALB2BIOGRID;

interacts with

 PALB2HPRD;

interacts with

 PALB2MINT;

interacts with

 PLK1BIOGRID;

interacts with

 PLK1HPRD;

interacts with

 PMS1BIOGRID;

interacts with

 PMS2BIOGRID;

interacts with

 RAD23AMINT;

interacts with

 Rad51BIOGRID;

interacts with

 RAD51BIOGRID;

interacts with

 RAD51HPRD;

interacts with

 RAD51INTACT;

interacts with

 RAD51MINT;

interacts with

 RPA1BIOGRID;

interacts with

 RPA1HPRD;

interacts with

 SERPINH1BIOGRID;

interacts with

 SHFM1BIOGRID;

interacts with

 SHFM1HPRD;

interacts with

 SKP2BIOGRID;

interacts with

 SMAD2BIOGRID;

interacts with

 SP1BIOGRID;

interacts with

 STAT5ABIOGRID;

interacts with

 STAT5AHPRD;

interacts with

 TACC1HPRD;

interacts with

 TP53BIOGRID;

interacts with

 UQCCBIOGRID;

interacts with

 USP11BIOGRID;

interacts with

 WDR16HPRD;

interacts with

 XRCC3BIOGRID;

Metabolic Interaction   [Top]

There is no record for BRCA2

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 ATMREACTOME;

reacts with

 BLMREACTOME;

reacts with

 BRCA1REACTOME;

reacts with

 BRCA2NCI_NATURE;

reacts with

 BRCA2REACTOME;

reacts with

 CDK2REACTOME;

reacts with

 CDK4REACTOME;

reacts with

 DMC1REACTOME;

reacts with

 FANCD2NCI_NATURE;

reacts with

 FANCGNCI_NATURE;

reacts with

 FANCINCI_NATURE;

reacts with

 H2AFXREACTOME;

reacts with

 HIST3H3REACTOME;

reacts with

 MLH1REACTOME;

reacts with

 MLH3REACTOME;

reacts with

 MSH4REACTOME;

reacts with

 MSH5REACTOME;

reacts with

 PALB2NCI_NATURE;

reacts with

 PALB2REACTOME;

reacts with

 RAD51NCI_NATURE;

reacts with

 RAD51REACTOME;

reacts with

 RPA1REACTOME;

reacts with

 RPA2REACTOME;

reacts with

 RPA3REACTOME;

reacts with

 TOP3AREACTOME;

reacts with

 XRCC3NCI_NATURE;

state change

 ATMREACTOME;

state change

 BRCA1REACTOME;

state change

 BRCA2REACTOME;

state change

 CDK4REACTOME;

state change

 CHEK1NCI_NATURE;

state change

 DMC1REACTOME;

state change

 H2AFXREACTOME;

state change

 HIST3H3REACTOME;

state change

 MND1REACTOME;

state change

 PSMC3IPREACTOME;

state change

 RAD51REACTOME;

state change

 RAD51CREACTOME;

state change

 RPA1REACTOME;

state change

 RPA2REACTOME;

state change

 RPA3REACTOME;

state change

 TEX15REACTOME;

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