Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	100132074
Name	FOXO6
Synonymous	forkhead box O6;FOXO6;forkhead box O6
Definition	forkhead box protein O6
Position	1p34.2
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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There is no record for FOXO6

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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Loss of Function mutations compare to missense mutation.

The ratio of the loss-of-function mutations over missense mutations is 0.00.

The copy number variations for various cancers

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There is no record for FOXO6

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.536G>T; p.R179L; 1:41381737-41381737	liver	carcinoma	Substitution - Missense
c.1423G>A; p.A475T; 1:41382624-41382624	thyroid	other; neoplasm	Substitution - Missense
c.876G>C; p.S292S; 1:41382077-41382077	ovary	other; neoplasm	Substitution - coding silent
c.876G>C; p.S292S; 1:41382077-41382077	ovary	other; neoplasm	Substitution - coding silent
c.1406G>T; p.R469L; 1:41382607-41382607	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.998G>C; p.R333P; 1:41382199-41382199	liver	carcinoma	Substitution - Missense
c.1187C>T; p.A396V; 1:41382388-41382388	thyroid	other; neoplasm	Substitution - Missense
c.1187C>T; p.A396V; 1:41382388-41382388	thyroid	other; neoplasm	Substitution - Missense
c.585G>C; p.K195N; 1:41381786-41381786	ovary	other; neoplasm	Substitution - Missense

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