Entrez Gene

Basic Information
Gene ID	11083
Name	DIDO1
Synonymous	death inducer-obliterator 1;DIDO1;death inducer-obliterator 1
Definition	death-associated transcription factor 1\|death-inducer obliterator 1
Position	20q13.33
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.08.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1477G>A; p.G493R; 20:62905998-62905998	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4225G>T; p.E1409*; 20:62881731-62881731	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4685A>T; p.Q1562L; 20:62881271-62881271	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4551G>T; p.S1517S; 20:62881405-62881405	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4152A>G; p.P1384P; 20:62881804-62881804	breast	carcinoma	Substitution - coding silent
c.248G>A; p.R83H; 20:62911365-62911365	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1366G>A; p.G456S; 20:62907155-62907155	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3779C>T; p.S1260L; 20:62882177-62882177	skin	malignant_melanoma	Substitution - Missense
c.248G>A; p.R83H; 20:62911365-62911365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5299C>T; p.H1767Y; 20:62880657-62880657	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6146C>T; p.A2049V; 20:62879810-62879810	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6020C>T; p.S2007L; 20:62879936-62879936	skin	malignant_melanoma	Substitution - Missense
c.5543C>T; p.P1848L; 20:62880413-62880413	skin	malignant_melanoma	Substitution - Missense
c.2647T>C; p.L883L; 20:62894120-62894120	pancreas	carcinoma	Substitution - coding silent
c.6523C>A; p.R2175R; 20:62879433-62879433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2914C>T; p.P972S; 20:62893853-62893853	skin	malignant_melanoma	Substitution - Missense
c.2914C>T; p.P972S; 20:62893853-62893853	skin	malignant_melanoma	Substitution - Missense
c.6020C>T; p.S2007L; 20:62879936-62879936	skin	malignant_melanoma	Substitution - Missense
c.2647T>C; p.L883L; 20:62894120-62894120	pancreas	carcinoma	Substitution - coding silent
c.2647T>C; p.L883L; 20:62894120-62894120	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.3439G>T; p.G1147C; 20:62891062-62891062	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4605C>G; p.F1535L; 20:62881351-62881351	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1715delC; p.S572fs*67; 20:62896870-62896870	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5652C>T; p.G1884G; 20:62880304-62880304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1622C>T; p.A541V; 20:62896963-62896963	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1622C>T; p.A541V; 20:62896963-62896963	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5324G>C; p.R1775T; 20:62880632-62880632	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.32A>T; p.E11V; 20:62911581-62911581	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.1702C>T; p.P568S; 20:62896883-62896883	skin	malignant_melanoma	Substitution - Missense
c.2581C>T; p.P861S; 20:62894186-62894186	skin	malignant_melanoma	Substitution - Missense
c.1702C>T; p.P568S; 20:62896883-62896883	skin	malignant_melanoma	Substitution - Missense
c.664G>A; p.D222N; 20:62910949-62910949	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2892C>T; p.S964S; 20:62893875-62893875	skin	malignant_melanoma	Substitution - coding silent
c.633C>T; p.G211G; 20:62910980-62910980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2892C>T; p.S964S; 20:62893875-62893875	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.633C>T; p.G211G; 20:62910980-62910980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3986A>T; p.D1329V; 20:62881970-62881970	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.792C>T; p.Y264Y; 20:62910821-62910821	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.664G>A; p.D222N; 20:62910949-62910949	thyroid	carcinoma	Substitution - Missense
c.5359G>A; p.A1787T; 20:62880597-62880597	skin	malignant_melanoma	Substitution - Missense
c.210C>T; p.R70R; 20:62911403-62911403	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1412C>A; p.A471D; 20:62906063-62906063	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.418G>C; p.E140Q; 20:62911195-62911195	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6296C>A; p.P2099Q; 20:62879660-62879660	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3791C>T; p.P1264L; 20:62882165-62882165	skin	malignant_melanoma	Substitution - Missense
c.453C>T; p.T151T; 20:62911160-62911160	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3218C>T; p.A1073V; 20:62892846-62892846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3218C>T; p.A1073V; 20:62892846-62892846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2496C>T; p.V832V; 20:62894489-62894489	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3541+6C>T; p.?; 20:62890954-62890954	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3541+6C>T; p.?; 20:62890954-62890954	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.3776G>T; p.G1259V; 20:62882180-62882180	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3218C>T; p.A1073V; 20:62892846-62892846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6619C>T; p.R2207W; 20:62879337-62879337	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5649C>T; p.G1883G; 20:62880307-62880307	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6184G>A; p.D2062N; 20:62879772-62879772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4220G>A; p.R1407H; 20:62881736-62881736	skin	malignant_melanoma	Substitution - Missense
c.6358G>A; p.G2120S; 20:62879598-62879598	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3102-1G>T; p.?; 20:62892963-62892963	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.1979G>A; p.S660N; 20:62896606-62896606	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4516G>A; p.A1506T; 20:62881440-62881440	breast	carcinoma	Substitution - Missense
c.5058G>A; p.P1686P; 20:62880898-62880898	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4862C>T; p.S1621L; 20:62881094-62881094	urinary_tract; bladder	carcinoma	Substitution - Missense
c.6349C>T; p.R2117C; 20:62879607-62879607	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1148A>C; p.K383T; 20:62909712-62909712	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6161C>T; p.A2054V; 20:62879795-62879795	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6161C>T; p.A2054V; 20:62879795-62879795	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.908G>A; p.R303Q; 20:62909952-62909952	NS	NS	Substitution - Missense
c.1631T>C; p.M544T; 20:62896954-62896954	breast	carcinoma	Substitution - Missense
c.5388G>C; p.P1796P; 20:62880568-62880568	thyroid	other; neoplasm	Substitution - coding silent
c.1008G>T; p.Q336H; 20:62909852-62909852	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4061T>G; p.V1354G; 20:62881895-62881895	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3496G>A; p.A1166T; 20:62891005-62891005	pancreas	carcinoma	Substitution - Missense
c.1389C>A; p.I463I; 20:62906086-62906086	breast	carcinoma	Substitution - coding silent
c.697G>A; p.D233N; 20:62910916-62910916	breast	carcinoma	Substitution - Missense
c.4057G>A; p.G1353R; 20:62881899-62881899	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3595delA; p.I1199fs*10; 20:62882361-62882361	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3595delA; p.I1199fs*10; 20:62882361-62882361	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4008C>T; p.P1336P; 20:62881948-62881948	skin; neck	malignant_melanoma	Substitution - coding silent
c.5426C>A; p.S1809Y; 20:62880530-62880530	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1804G>A; p.A602T; 20:62896781-62896781	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4275C>A; p.A1425A; 20:62881681-62881681	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4932C>T; p.P1644P; 20:62881024-62881024	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4618C>T; p.Q1540*; 20:62881338-62881338	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.638T>C; p.L213P; 20:62910975-62910975	skin	malignant_melanoma	Substitution - Missense
c.4407G>A; p.T1469T; 20:62881549-62881549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.77C>T; p.T26I; 20:62911536-62911536	breast	carcinoma	Substitution - Missense
c.1568C>T; p.S523L; 20:62905907-62905907	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2535C>T; p.R845R; 20:62894450-62894450	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4430A>C; p.K1477T; 20:62881526-62881526	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4065G>T; p.P1355P; 20:62881891-62881891	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2319G>C; p.R773S; 20:62895061-62895061	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3082C>T; p.P1028S; 20:62893685-62893685	skin	malignant_melanoma	Substitution - Missense
c.6228C>T; p.H2076H; 20:62879728-62879728	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.483G>C; p.L161F; 20:62911130-62911130	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4548G>T; p.V1516V; 20:62881408-62881408	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.4983C>T; p.P1661P; 20:62880973-62880973	skin	malignant_melanoma	Substitution - coding silent
c.326C>T; p.T109I; 20:62911287-62911287	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.901G>A; p.E301K; 20:62909959-62909959	urinary_tract; bladder	carcinoma	Substitution - Missense
c.374C>A; p.P125H; 20:62911239-62911239	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1770C>T; p.F590F; 20:62896815-62896815	skin	malignant_melanoma	Substitution - coding silent
c.4372G>T; p.E1458*; 20:62881584-62881584	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.5054G>T; p.C1685F; 20:62880902-62880902	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.175C>T; p.L59L; 20:62911438-62911438	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.175C>T; p.L59L; 20:62911438-62911438	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.175C>T; p.L59L; 20:62911438-62911438	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.6248_6249insT; p.E2084fs*9; 20:62879707-62879708	endometrium	carcinoma; endometrioid_carcinoma	Insertion - Frameshift
c.3394G>A; p.A1132T; 20:62891107-62891107	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4897G>A; p.G1633S; 20:62881059-62881059	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6175C>G; p.P2059A; 20:62879781-62879781	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3660G>T; p.P1220P; 20:62882296-62882296	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.5901C>T; p.F1967F; 20:62880055-62880055	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3733C>T; p.P1245S; 20:62882223-62882223	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5549G>C; p.G1850A; 20:62880407-62880407	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5901C>T; p.F1967F; 20:62880055-62880055	skin	malignant_melanoma	Substitution - coding silent
c.1545G>T; p.K515N; 20:62905930-62905930	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6066C>T; p.G2022G; 20:62879890-62879890	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4097A>T; p.Q1366L; 20:62881859-62881859	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.5769C>T; p.F1923F; 20:62880187-62880187	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4406C>T; p.T1469M; 20:62881550-62881550	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.4952C>T; p.S1651L; 20:62881004-62881004	skin	malignant_melanoma	Substitution - Missense
c.2176C>T; p.R726C; 20:62896271-62896271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5139C>T; p.S1713S; 20:62880817-62880817	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2176C>T; p.R726C; 20:62896271-62896271	skin	malignant_melanoma	Substitution - Missense
c.1425_1426insA; p.E476fs*15; 20:62906049-62906050	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.473G>T; p.G158V; 20:62911140-62911140	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5200G>T; p.A1734S; 20:62880756-62880756	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.3957G>A; p.Q1319Q; 20:62881999-62881999	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1658C>T; p.P553L; 20:62896927-62896927	NS	malignant_melanoma	Substitution - Missense
c.1978A>G; p.S660G; 20:62896607-62896607	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.219C>T; p.R73R; 20:62911394-62911394	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6326C>T; p.A2109V; 20:62879630-62879630	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3373G>A; p.A1125T; 20:62891128-62891128	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5247G>A; p.P1749P; 20:62880709-62880709	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3505C>A; p.P1169T; 20:62890996-62890996	ovary	carcinoma	Substitution - Missense
c.5161G>C; p.G1721R; 20:62880795-62880795	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.6357C>T; p.R2119R; 20:62879599-62879599	large_intestine; rectum	adenoma	Substitution - coding silent
c.4521C>T; p.V1507V; 20:62881435-62881435	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4225G>A; p.E1409K; 20:62881731-62881731	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4225G>A; p.E1409K; 20:62881731-62881731	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.878A>G; p.H293R; 20:62909982-62909982	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2553C>T; p.L851L; 20:62894432-62894432	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1525C>T; p.H509Y; 20:62905950-62905950	skin	malignant_melanoma	Substitution - Missense
c.1940C>T; p.P647L; 20:62896645-62896645	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2984G>C; p.R995T; 20:62893783-62893783	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2011C>T; p.R671W; 20:62896574-62896574	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.5400C>T; p.F1800F; 20:62880556-62880556	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2011C>T; p.R671W; 20:62896574-62896574	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2327G>A; p.R776K; 20:62895053-62895053	NS	NS	Substitution - Missense
c.1992G>A; p.S664S; 20:62896593-62896593	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5998G>A; p.E2000K; 20:62879958-62879958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5996C>T; p.S1999F; 20:62879960-62879960	skin	malignant_melanoma	Substitution - Missense
c.5435C>T; p.S1812L; 20:62880521-62880521	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.5338C>T; p.P1780S; 20:62880618-62880618	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.663C>T; p.N221N; 20:62910950-62910950	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.275_276CC>TT; p.S92F; 20:62911337-62911338	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3119C>T; p.S1040F; 20:62892945-62892945	skin; trunk	malignant_melanoma	Substitution - Missense
c.5056C>T; p.P1686S; 20:62880900-62880900	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4524G>A; p.G1508G; 20:62881432-62881432	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3914C>T; p.S1305L; 20:62882042-62882042	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.6579G>A; p.R2193R; 20:62879377-62879377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3914C>T; p.S1305L; 20:62882042-62882042	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2534G>A; p.R845H; 20:62894451-62894451	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3914C>T; p.S1305L; 20:62882042-62882042	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3914C>T; p.S1305L; 20:62882042-62882042	skin	malignant_melanoma	Substitution - Missense
c.2236C>T; p.R746C; 20:62895144-62895144	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6512G>A; p.R2171H; 20:62879444-62879444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3165C>T; p.T1055T; 20:62892899-62892899	skin	malignant_melanoma	Substitution - coding silent
c.4325A>T; p.D1442V; 20:62881631-62881631	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5308A>G; p.N1770D; 20:62880648-62880648	skin	malignant_melanoma	Substitution - Missense
c.4509G>A; p.Q1503Q; 20:62881447-62881447	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.172G>T; p.G58C; 20:62911441-62911441	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6451C>T; p.R2151W; 20:62879505-62879505	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4024C>T; p.L1342F; 20:62881932-62881932	skin	malignant_melanoma	Substitution - Missense
c.943A>G; p.I315V; 20:62909917-62909917	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5812C>T; p.R1938W; 20:62880144-62880144	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4172A>G; p.Y1391C; 20:62881784-62881784	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3797delC; p.P1266fs*8; 20:62882159-62882159	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5824C>T; p.P1942S; 20:62880132-62880132	skin	malignant_melanoma	Substitution - Missense
c.4990C>T; p.P1664S; 20:62880966-62880966	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5893C>G; p.Q1965E; 20:62880063-62880063	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4699G>C; p.A1567P; 20:62881257-62881257	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2407G>T; p.E803*; 20:62894839-62894839	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2614_2615insA; p.L874fs*6; 20:62894152-62894153	stomach	carcinoma; diffuse_adenocarcinoma	Insertion - Frameshift
c.436G>T; p.D146Y; 20:62911177-62911177	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.5544C>T; p.P1848P; 20:62880412-62880412	skin	malignant_melanoma	Substitution - coding silent
c.2969A>G; p.H990R; 20:62893798-62893798	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2689G>C; p.D897H; 20:62894078-62894078	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1666G>A; p.A556T; 20:62896919-62896919	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1666G>A; p.A556T; 20:62896919-62896919	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1105A>G; p.R369G; 20:62909755-62909755	prostate	carcinoma	Substitution - Missense
c.732G>A; p.Q244Q; 20:62910881-62910881	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2823C>T; p.S941S; 20:62893944-62893944	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3131delG; p.G1044fs*76; 20:62892933-62892933	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.110G>A; p.R37Q; 20:62911503-62911503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2104A>G; p.I702V; 20:62896343-62896343	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2841C>T; p.S947S; 20:62893926-62893926	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4927_4928insC; p.R1643fs*37; 20:62881028-62881029	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4927_4928insC; p.R1643fs*37; 20:62881028-62881029	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4927_4928insC; p.R1643fs*37; 20:62881028-62881029	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4927_4928insC; p.R1643fs*37; 20:62881028-62881029	NS	malignant_melanoma	Insertion - Frameshift
c.4927_4928insC; p.R1643fs*37; 20:62881028-62881029	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.3707A>G; p.Q1236R; 20:62882249-62882249	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1136A>T; p.K379M; 20:62909724-62909724	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4854C>T; p.P1618P; 20:62881102-62881102	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2163C>T; p.Y721Y; 20:62896284-62896284	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.4542C>T; p.F1514F; 20:62881414-62881414	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1502G>C; p.S501T; 20:62905973-62905973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3534G>T; p.E1178D; 20:62890967-62890967	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6627C>T; p.R2209R; 20:62879329-62879329	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1698C>T; p.L566L; 20:62896887-62896887	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.4101C>T; p.F1367F; 20:62881855-62881855	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1660G>T; p.G554C; 20:62896925-62896925	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1738A>T; p.T580S; 20:62896847-62896847	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4258G>A; p.E1420K; 20:62881698-62881698	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.543G>A; p.L181L; 20:62911070-62911070	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4351G>C; p.D1451H; 20:62881605-62881605	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4258G>A; p.E1420K; 20:62881698-62881698	NS	NS	Substitution - Missense
c.1839G>T; p.Q613H; 20:62896746-62896746	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5213C>T; p.P1738L; 20:62880743-62880743	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3999A>G; p.R1333R; 20:62881957-62881957	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3482T>G; p.L1161R; 20:62891019-62891019	breast	carcinoma	Substitution - Missense
c.1802C>T; p.S601F; 20:62896783-62896783	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2723C>T; p.P908L; 20:62894044-62894044	skin	malignant_melanoma	Substitution - Missense
c.6665G>A; p.R2222Q; 20:62879291-62879291	skin; mucosal	malignant_melanoma	Substitution - Missense
c.5768T>G; p.F1923C; 20:62880188-62880188	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4544C>T; p.S1515L; 20:62881412-62881412	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6490G>A; p.D2164N; 20:62879466-62879466	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3718A>C; p.K1240Q; 20:62882238-62882238	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3270A>C; p.T1090T; 20:62892062-62892062	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6547C>T; p.R2183*; 20:62879409-62879409	pancreas	carcinoma	Substitution - Nonsense
c.2842C>T; p.P948S; 20:62893925-62893925	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2893G>T; p.G965C; 20:62893874-62893874	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3488C>T; p.P1163L; 20:62891013-62891013	skin	malignant_melanoma	Substitution - Missense
c.4711G>A; p.G1571S; 20:62881245-62881245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2761C>T; p.H921Y; 20:62894006-62894006	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4330C>T; p.L1444L; 20:62881626-62881626	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1145T>G; p.L382R; 20:62909715-62909715	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1358C>T; p.P453L; 20:62907163-62907163	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1358C>T; p.P453L; 20:62907163-62907163	skin	malignant_melanoma	Substitution - Missense
c.1980T>C; p.S660S; 20:62896605-62896605	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4702A>G; p.T1568A; 20:62881254-62881254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4702A>G; p.T1568A; 20:62881254-62881254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4702A>G; p.T1568A; 20:62881254-62881254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4702A>G; p.T1568A; 20:62881254-62881254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5313C>T; p.F1771F; 20:62880643-62880643	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4702A>G; p.T1568A; 20:62881254-62881254	thyroid	other; neoplasm	Substitution - Missense
c.3192G>C; p.Q1064H; 20:62892872-62892872	urinary_tract; bladder	carcinoma	Substitution - Missense
c.5548G>T; p.G1850W; 20:62880408-62880408	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5019G>C; p.P1673P; 20:62880937-62880937	thyroid	carcinoma	Substitution - coding silent
c.5870C>T; p.P1957L; 20:62880086-62880086	skin	malignant_melanoma	Substitution - Missense
c.4126C>G; p.L1376V; 20:62881830-62881830	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6118C>T; p.R2040C; 20:62879838-62879838	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1271C>T; p.A424V; 20:62907250-62907250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1860G>T; p.A620A; 20:62896725-62896725	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4847C>T; p.S1616F; 20:62881109-62881109	skin	malignant_melanoma	Substitution - Missense
c.4056C>T; p.D1352D; 20:62881900-62881900	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3751G>A; p.A1251T; 20:62882205-62882205	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3751G>A; p.A1251T; 20:62882205-62882205	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4493A>G; p.E1498G; 20:62881463-62881463	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1715_1717delCTT; p.S572delS; 20:62896868-62896870	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.3751G>A; p.A1251T; 20:62882205-62882205	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3751G>A; p.A1251T; 20:62882205-62882205	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4368C>T; p.S1456S; 20:62881588-62881588	skin	malignant_melanoma	Substitution - coding silent
c.5597C>T; p.A1866V; 20:62880359-62880359	pancreas	carcinoma	Substitution - Missense
c.6249C>T; p.F2083F; 20:62879707-62879707	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2157T>G; p.N719K; 20:62896290-62896290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3204A>G; p.K1068K; 20:62892860-62892860	liver	carcinoma	Substitution - coding silent
c.3204A>G; p.K1068K; 20:62892860-62892860	liver	carcinoma	Substitution - coding silent
c.128C>T; p.A43V; 20:62911485-62911485	liver	carcinoma	Substitution - Missense
c.6249C>T; p.F2083F; 20:62879707-62879707	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.128C>T; p.A43V; 20:62911485-62911485	liver	carcinoma	Substitution - Missense
c.3813_3814GG>AA; p.V1272M; 20:62882142-62882143	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1140G>A; p.K380K; 20:62909720-62909720	thyroid	other; neoplasm	Substitution - coding silent
c.1712_1713delCT; p.S571fs*4; 20:62896872-62896873	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.6165C>T; p.P2055P; 20:62879791-62879791	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - coding silent
c.188G>A; p.R63H; 20:62911425-62911425	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.184C>T; p.R62W; 20:62911429-62911429	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1912G>A; p.V638I; 20:62896673-62896673	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5158G>A; p.E1720K; 20:62880798-62880798	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4866C>T; p.G1622G; 20:62881090-62881090	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.184C>T; p.R62W; 20:62911429-62911429	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5347G>A; p.E1783K; 20:62880609-62880609	central_nervous_system; brain	glioma	Substitution - Missense
c.5158G>A; p.E1720K; 20:62880798-62880798	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2540A>G; p.H847R; 20:62894445-62894445	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2713G>A; p.E905K; 20:62894054-62894054	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5990C>A; p.P1997H; 20:62879966-62879966	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5379A>G; p.R1793R; 20:62880577-62880577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6666G>T; p.R2222R; 20:62879290-62879290	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.5379A>G; p.R1793R; 20:62880577-62880577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.502C>T; p.L168F; 20:62911111-62911111	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1094G>T; p.G365V; 20:62909766-62909766	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2865C>T; p.S955S; 20:62893902-62893902	liver	carcinoma	Substitution - coding silent
c.1910C>T; p.A637V; 20:62896675-62896675	skin	malignant_melanoma	Substitution - Missense
c.784G>A; p.E262K; 20:62910829-62910829	breast	carcinoma	Substitution - Missense
c.6258G>T; p.R2086S; 20:62879698-62879698	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2301T>C; p.L767L; 20:62895079-62895079	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2133T>A; p.F711L; 20:62896314-62896314	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1046A>T; p.D349V; 20:62909814-62909814	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2301T>C; p.L767L; 20:62895079-62895079	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2306C>T; p.T769M; 20:62895074-62895074	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2227C>T; p.R743C; 20:62895153-62895153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.220G>T; p.V74L; 20:62911393-62911393	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2650A>T; p.K884*; 20:62894117-62894117	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.5893C>T; p.Q1965*; 20:62880063-62880063	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.4572A>C; p.P1524P; 20:62881384-62881384	breast	carcinoma	Substitution - coding silent
c.1169A>C; p.E390A; 20:62907352-62907352	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1247A>G; p.D416G; 20:62907274-62907274	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.332C>T; p.S111F; 20:62911281-62911281	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6101C>T; p.P2034L; 20:62879855-62879855	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2688G>A; p.P896P; 20:62894079-62894079	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4449C>T; p.N1483N; 20:62881507-62881507	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5206C>T; p.L1736F; 20:62880750-62880750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2239G>C; p.E747Q; 20:62895141-62895141	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4324G>C; p.D1442H; 20:62881632-62881632	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3561G>A; p.P1187P; 20:62882395-62882395	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5872G>T; p.G1958C; 20:62880084-62880084	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4148G>A; p.R1383K; 20:62881808-62881808	skin	malignant_melanoma	Substitution - Missense
c.3857C>T; p.P1286L; 20:62882099-62882099	skin	malignant_melanoma	Substitution - Missense
c.5574C>T; p.A1858A; 20:62880382-62880382	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5032G>A; p.G1678S; 20:62880924-62880924	skin	malignant_melanoma	Substitution - Missense
c.6088C>T; p.P2030S; 20:62879868-62879868	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3116G>T; p.R1039L; 20:62892948-62892948	liver	carcinoma	Substitution - Missense
c.1815G>A; p.S605S; 20:62896770-62896770	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.523G>A; p.E175K; 20:62911090-62911090	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3530T>G; p.F1177C; 20:62890971-62890971	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4771C>T; p.P1591S; 20:62881185-62881185	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.893G>A; p.G298D; 20:62909967-62909967	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1290C>T; p.S430S; 20:62907231-62907231	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3862_3873del12; p.T1291_A1294delTTAA; 20:62882083-62882094	kidney	carcinoma; renal_cell_carcinoma	Deletion - In frame
c.3116G>T; p.R1039L; 20:62892948-62892948	liver	carcinoma	Substitution - Missense
c.5587G>T; p.V1863L; 20:62880369-62880369	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4485G>T; p.E1495D; 20:62881471-62881471	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6376G>A; p.E2126K; 20:62879580-62879580	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2481G>A; p.A827A; 20:62894504-62894504	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1889G>A; p.G630D; 20:62896696-62896696	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3689A>C; p.K1230T; 20:62882267-62882267	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.403C>T; p.R135*; 20:62911210-62911210	breast	carcinoma	Substitution - Nonsense
c.5339C>G; p.P1780R; 20:62880617-62880617	skin	malignant_melanoma	Substitution - Missense
c.1570C>T; p.P524S; 20:62905905-62905905	skin	malignant_melanoma	Substitution - Missense
c.5414G>A; p.G1805E; 20:62880542-62880542	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2607G>A; p.P869P; 20:62894160-62894160	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.575G>A; p.R192H; 20:62911038-62911038	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5700G>C; p.L1900L; 20:62880256-62880256	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3738C>T; p.L1246L; 20:62882218-62882218	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.686C>T; p.A229V; 20:62910927-62910927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.622A>G; p.T208A; 20:62910991-62910991	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4787C>T; p.S1596F; 20:62881169-62881169	skin	malignant_melanoma	Substitution - Missense
c.2417C>T; p.P806L; 20:62894829-62894829	prostate	carcinoma	Substitution - Missense
c.4850C>T; p.S1617F; 20:62881106-62881106	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4236G>C; p.R1412S; 20:62881720-62881720	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4968G>A; p.R1656R; 20:62880988-62880988	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4492G>C; p.E1498Q; 20:62881464-62881464	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3781C>T; p.P1261S; 20:62882175-62882175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1172C>T; p.A391V; 20:62907349-62907349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.322G>T; p.E108*; 20:62911291-62911291	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2536G>T; p.A846S; 20:62894449-62894449	liver	carcinoma	Substitution - Missense
c.2536G>T; p.A846S; 20:62894449-62894449	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.129G>A; p.A43A; 20:62911484-62911484	breast	carcinoma	Substitution - coding silent
c.2536G>T; p.A846S; 20:62894449-62894449	liver	carcinoma	Substitution - Missense
c.4153T>C; p.Y1385H; 20:62881803-62881803	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.338_339insG; p.S114fs*7; 20:62911274-62911275	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1600G>A; p.D534N; 20:62896985-62896985	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5500C>T; p.P1834S; 20:62880456-62880456	skin; trunk	malignant_melanoma	Substitution - Missense
c.2427G>T; p.S809S; 20:62894819-62894819	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.6152C>T; p.S2051F; 20:62879804-62879804	skin	malignant_melanoma	Substitution - Missense
c.1991C>T; p.S664L; 20:62896594-62896594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1738A>C; p.T580P; 20:62896847-62896847	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.5339C>T; p.P1780L; 20:62880617-62880617	skin	malignant_melanoma	Substitution - Missense
c.457G>A; p.D153N; 20:62911156-62911156	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1592C>T; p.T531M; 20:62896993-62896993	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2380C>T; p.P794S; 20:62894866-62894866	skin	malignant_melanoma	Substitution - Missense
c.3154C>T; p.R1052*; 20:62892910-62892910	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.5869C>T; p.P1957S; 20:62880087-62880087	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5611G>A; p.E1871K; 20:62880345-62880345	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3154C>T; p.R1052*; 20:62892910-62892910	thyroid	carcinoma	Substitution - Nonsense
c.1691G>C; p.R564T; 20:62896894-62896894	breast	carcinoma	Substitution - Missense
c.5010C>T; p.P1670P; 20:62880946-62880946	liver	carcinoma	Substitution - coding silent
c.6291G>A; p.E2097E; 20:62879665-62879665	skin	malignant_melanoma	Substitution - coding silent
c.5010C>T; p.P1670P; 20:62880946-62880946	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2797C>T; p.P933S; 20:62893970-62893970	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6637G>A; p.D2213N; 20:62879319-62879319	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.6176C>T; p.P2059L; 20:62879780-62879780	skin	malignant_melanoma	Substitution - Missense
c.4333C>T; p.P1445S; 20:62881623-62881623	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.88C>T; p.R30*; 20:62911525-62911525	skin	malignant_melanoma	Substitution - Nonsense
c.3900T>C; p.A1300A; 20:62882056-62882056	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.88C>T; p.R30*; 20:62911525-62911525	skin	malignant_melanoma	Substitution - Nonsense
c.4351G>T; p.D1451Y; 20:62881605-62881605	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1791G>A; p.R597R; 20:62896794-62896794	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3192G>A; p.Q1064Q; 20:62892872-62892872	breast	carcinoma	Substitution - coding silent
c.4117G>T; p.D1373Y; 20:62881839-62881839	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6486G>A; p.E2162E; 20:62879470-62879470	pancreas	carcinoma	Substitution - coding silent
c.3938C>T; p.P1313L; 20:62882018-62882018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.5023C>T; p.Q1675*; 20:62880933-62880933	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.5533C>T; p.R1845C; 20:62880423-62880423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.6119G>A; p.R2040H; 20:62879837-62879837	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.6380G>A; p.R2127Q; 20:62879576-62879576	skin	malignant_melanoma	Substitution - Missense
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4878_4879insC; p.A1627fs*53; 20:62881077-62881078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3610_3611AA>GC; p.N1204A; 20:62882345-62882346	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3286A>T; p.R1096W; 20:62892046-62892046	pancreas	carcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1487C>T; p.A496V; 20:62905988-62905988	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4872G>C; p.K1624N; 20:62881084-62881084	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4412C>T; p.S1471F; 20:62881544-62881544	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2669C>G; p.S890C; 20:62894098-62894098	thyroid	other; neoplasm	Substitution - Missense
c.3809C>T; p.P1270L; 20:62882147-62882147	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2938G>A; p.A980T; 20:62893829-62893829	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3809C>T; p.P1270L; 20:62882147-62882147	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2755_2756GC>AT; p.A919>?; 20:62894011-62894012	large_intestine; colon	carcinoma; adenocarcinoma	Complex
c.3856C>T; p.P1286S; 20:62882100-62882100	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1083C>T; p.S361S; 20:62909777-62909777	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5546A>T; p.H1849L; 20:62880410-62880410	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1217C>T; p.A406V; 20:62907304-62907304	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6121T>C; p.W2041R; 20:62879835-62879835	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4310C>T; p.A1437V; 20:62881646-62881646	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2307G>A; p.T769T; 20:62895073-62895073	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5891C>T; p.P1964L; 20:62880065-62880065	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6428C>T; p.S2143F; 20:62879528-62879528	skin	malignant_melanoma	Substitution - Missense
c.25A>G; p.N9D; 20:62911588-62911588	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4180G>A; p.E1394K; 20:62881776-62881776	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1399C>A; p.H467N; 20:62906076-62906076	liver	carcinoma	Substitution - Missense
c.1399C>A; p.H467N; 20:62906076-62906076	liver	carcinoma	Substitution - Missense
c.5667C>T; p.F1889F; 20:62880289-62880289	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3881C>A; p.A1294E; 20:62882075-62882075	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6101delC; p.P2034fs*>207; 20:62879855-62879855	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5402G>A; p.G1801E; 20:62880554-62880554	skin	malignant_melanoma	Substitution - Missense
c.6101delC; p.P2034fs*>207; 20:62879855-62879855	thyroid	carcinoma; anaplastic_carcinoma	Deletion - Frameshift
c.6101delC; p.P2034fs*>207; 20:62879855-62879855	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3785C>T; p.P1262L; 20:62882171-62882171	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1863A>G; p.A621A; 20:62896722-62896722	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.4037C>T; p.P1346L; 20:62881919-62881919	skin; mucosal	malignant_melanoma	Substitution - Missense
c.117C>T; p.G39G; 20:62911496-62911496	ovary	other; neoplasm	Substitution - coding silent
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3627C>T; p.D1209D; 20:62882329-62882329	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5727C>T; p.P1909P; 20:62880229-62880229	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4924A>C; p.T1642P; 20:62881032-62881032	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1610C>T; p.S537F; 20:62896975-62896975	skin	malignant_melanoma	Substitution - Missense
c.3330G>C; p.K1110N; 20:62892002-62892002	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.4066G>T; p.A1356S; 20:62881890-62881890	meninges	meningioma	Substitution - Missense
c.2511G>C; p.L837F; 20:62894474-62894474	breast	carcinoma	Substitution - Missense
c.3750C>G; p.D1250E; 20:62882206-62882206	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2511G>C; p.L837F; 20:62894474-62894474	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4707G>A; p.E1569E; 20:62881249-62881249	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2630C>T; p.S877F; 20:62894137-62894137	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5471G>C; p.R1824T; 20:62880485-62880485	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4231G>C; p.E1411Q; 20:62881725-62881725	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2630C>T; p.S877F; 20:62894137-62894137	skin	malignant_melanoma	Substitution - Missense
c.3802C>T; p.P1268S; 20:62882154-62882154	skin	malignant_melanoma	Substitution - Missense
c.365G>C; p.R122T; 20:62911248-62911248	breast	carcinoma	Substitution - Missense
c.1740A>C; p.T580T; 20:62896845-62896845	thyroid	other; neoplasm	Substitution - coding silent
c.6686C>T; p.S2229L; 20:62879270-62879270	skin	malignant_melanoma	Substitution - Missense
c.4552G>A; p.D1518N; 20:62881404-62881404	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1740A>C; p.T580T; 20:62896845-62896845	thyroid	other; neoplasm	Substitution - coding silent
c.1740A>C; p.T580T; 20:62896845-62896845	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1740A>C; p.T580T; 20:62896845-62896845	thyroid	other; neoplasm	Substitution - coding silent
c.1740A>C; p.T580T; 20:62896845-62896845	thyroid	other; neoplasm	Substitution - coding silent
c.1740A>C; p.T580T; 20:62896845-62896845	thyroid	other; neoplasm	Substitution - coding silent
c.4110C>A; p.F1370L; 20:62881846-62881846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2133delT; p.F711fs*22; 20:62896314-62896314	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5372G>C; p.G1791A; 20:62880584-62880584	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.5423C>T; p.P1808L; 20:62880533-62880533	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4691G>T; p.R1564M; 20:62881265-62881265	thyroid	other; neoplasm	Substitution - Missense
c.444C>T; p.H148H; 20:62911169-62911169	pancreas	carcinoma	Substitution - coding silent
c.657C>T; p.P219P; 20:62910956-62910956	skin	malignant_melanoma	Substitution - coding silent
c.253G>A; p.G85S; 20:62911360-62911360	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4751G>A; p.R1584H; 20:62881205-62881205	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.G85S; 20:62911360-62911360	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2917A>G; p.S973G; 20:62893850-62893850	liver	carcinoma	Substitution - Missense
c.309_310CG>TT; p.A104S; 20:62911303-62911304	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5239C>G; p.Q1747E; 20:62880717-62880717	breast	carcinoma	Substitution - Missense
c.6489C>T; p.A2163A; 20:62879467-62879467	pancreas	carcinoma	Substitution - coding silent
c.5239C>G; p.Q1747E; 20:62880717-62880717	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6046C>T; p.P2016S; 20:62879910-62879910	skin	malignant_melanoma	Substitution - Missense
c.5648G>T; p.G1883V; 20:62880308-62880308	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4693C>T; p.R1565C; 20:62881263-62881263	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.6046C>T; p.P2016S; 20:62879910-62879910	skin	malignant_melanoma	Substitution - Missense
c.5440C>T; p.Q1814*; 20:62880516-62880516	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3911C>T; p.A1304V; 20:62882045-62882045	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6317A>G; p.Q2106R; 20:62879639-62879639	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3988C>T; p.P1330S; 20:62881968-62881968	skin; abdomen	malignant_melanoma	Substitution - Missense
c.5242C>A; p.P1748T; 20:62880714-62880714	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5291C>A; p.S1764*; 20:62880665-62880665	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3989C>T; p.P1330L; 20:62881967-62881967	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3989C>T; p.P1330L; 20:62881967-62881967	skin; abdomen	malignant_melanoma	Substitution - Missense
c.4413C>T; p.S1471S; 20:62881543-62881543	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.862T>C; p.C288R; 20:62909998-62909998	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1866G>T; p.T622T; 20:62896719-62896719	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3332C>T; p.S1111F; 20:62892000-62892000	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1834A>G; p.R612G; 20:62896751-62896751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1834A>G; p.R612G; 20:62896751-62896751	large_intestine; colon	carcinoma	Substitution - Missense
c.4515C>T; p.A1505A; 20:62881441-62881441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6352G>A; p.E2118K; 20:62879604-62879604	NS	NS	Substitution - Missense
c.483G>A; p.L161L; 20:62911130-62911130	breast	carcinoma	Substitution - coding silent
c.2067C>T; p.S689S; 20:62896380-62896380	pancreas	carcinoma	Substitution - coding silent
c.2067C>T; p.S689S; 20:62896380-62896380	pancreas	carcinoma	Substitution - coding silent
c.5710C>G; p.R1904G; 20:62880246-62880246	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2067C>T; p.S689S; 20:62896380-62896380	pancreas	carcinoma	Substitution - coding silent
c.5591C>T; p.T1864M; 20:62880365-62880365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.98C>T; p.T33I; 20:62911515-62911515	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1681C>T; p.P561S; 20:62896904-62896904	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.400G>C; p.E134Q; 20:62911213-62911213	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.11A>T; p.K4I; 20:62911602-62911602	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2436G>A; p.E812E; 20:62894810-62894810	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.133G>T; p.A45S; 20:62911480-62911480	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.5320C>T; p.P1774S; 20:62880636-62880636	skin	malignant_melanoma	Substitution - Missense
c.4795G>T; p.G1599C; 20:62881161-62881161	large_intestine; colon	adenoma	Substitution - Missense
c.3645G>A; p.R1215R; 20:62882311-62882311	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4044C>T; p.T1348T; 20:62881912-62881912	skin	malignant_melanoma	Substitution - coding silent
c.6206A>C; p.D2069A; 20:62879750-62879750	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1267G>A; p.A423T; 20:62907254-62907254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5757C>A; p.P1919P; 20:62880199-62880199	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.500G>A; p.R167H; 20:62911113-62911113	pancreas	carcinoma	Substitution - Missense
c.2480C>T; p.A827V; 20:62894505-62894505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.719G>A; p.G240E; 20:62910894-62910894	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2507T>C; p.M836T; 20:62894478-62894478	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1246G>A; p.D416N; 20:62907275-62907275	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1359G>A; p.P453P; 20:62907162-62907162	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4867G>A; p.E1623K; 20:62881089-62881089	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6596G>A; p.R2199Q; 20:62879360-62879360	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.882C>T; p.G294G; 20:62909978-62909978	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.6596G>A; p.R2199Q; 20:62879360-62879360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4441G>T; p.E1481*; 20:62881515-62881515	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1807A>C; p.T603P; 20:62896778-62896778	urinary_tract; bladder	carcinoma	Substitution - Missense
c.5758C>T; p.P1920S; 20:62880198-62880198	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.590C>T; p.P197L; 20:62911023-62911023	skin	malignant_melanoma	Substitution - Missense
c.3404C>T; p.S1135F; 20:62891097-62891097	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.440A>G; p.D147G; 20:62911173-62911173	skin	malignant_melanoma	Substitution - Missense
c.6122G>T; p.W2041L; 20:62879834-62879834	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4732C>T; p.L1578F; 20:62881224-62881224	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1087G>T; p.D363Y; 20:62909773-62909773	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1784C>G; p.P595R; 20:62896801-62896801	pancreas	carcinoma	Substitution - Missense
c.3345+1G>C; p.?; 20:62891986-62891986	breast	carcinoma	Unknown
c.2224C>T; p.H742Y; 20:62895156-62895156	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1665C>T; p.S555S; 20:62896920-62896920	skin	malignant_melanoma	Substitution - coding silent
c.3559C>T; p.P1187S; 20:62882397-62882397	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.558T>C; p.S186S; 20:62911055-62911055	skin	malignant_melanoma	Substitution - coding silent
c.3980C>A; p.S1327*; 20:62881976-62881976	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.5409G>T; p.Q1803H; 20:62880547-62880547	breast	carcinoma	Substitution - Missense
c.250C>T; p.R84C; 20:62911363-62911363	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5413_5414GG>AA; p.G1805K; 20:62880542-62880543	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.102C>T; p.I34I; 20:62911511-62911511	thyroid	other; neoplasm	Substitution - coding silent
c.4217G>A; p.R1406Q; 20:62881739-62881739	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6006_6007insA; p.E2003fs*90; 20:62879949-62879950	stomach	adenocarcinoma	Insertion - Frameshift
c.4896C>T; p.D1632D; 20:62881060-62881060	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6051G>T; p.Q2017H; 20:62879905-62879905	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5190C>T; p.G1730G; 20:62880766-62880766	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5228delT; p.V1743fs*121; 20:62880728-62880728	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.907C>T; p.R303*; 20:62909953-62909953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1052C>T; p.T351I; 20:62909808-62909808	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4739G>A; p.R1580K; 20:62881217-62881217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5682G>A; p.R1894R; 20:62880274-62880274	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4089C>T; p.I1363I; 20:62881867-62881867	skin	malignant_melanoma	Substitution - coding silent
c.6144C>T; p.S2048S; 20:62879812-62879812	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.5301C>T; p.H1767H; 20:62880655-62880655	ovary	other; neoplasm	Substitution - coding silent
c.2013G>A; p.R671R; 20:62896572-62896572	central_nervous_system; brain	glioma	Substitution - coding silent
c.2043T>G; p.I681M; 20:62896542-62896542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5301C>T; p.H1767H; 20:62880655-62880655	ovary	other; neoplasm	Substitution - coding silent
c.4470G>C; p.K1490N; 20:62881486-62881486	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.3393C>T; p.V1131V; 20:62891108-62891108	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.859C>T; p.R287C; 20:62910001-62910001	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.542T>G; p.L181R; 20:62911071-62911071	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4746G>A; p.S1582S; 20:62881210-62881210	pancreas	carcinoma	Substitution - coding silent
c.239T>G; p.I80S; 20:62911374-62911374	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4470G>C; p.K1490N; 20:62881486-62881486	urinary_tract; bladder	carcinoma	Substitution - Missense
c.246G>A; p.R82R; 20:62911367-62911367	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5523A>G; p.Q1841Q; 20:62880433-62880433	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.4451A>C; p.K1484T; 20:62881505-62881505	skin	malignant_melanoma	Substitution - Missense
c.4216C>T; p.R1406W; 20:62881740-62881740	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2877C>T; p.T959T; 20:62893890-62893890	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.469G>A; p.D157N; 20:62911144-62911144	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4216C>T; p.R1406W; 20:62881740-62881740	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1224C>T; p.P408P; 20:62907297-62907297	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5969G>A; p.G1990D; 20:62879987-62879987	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.998C>T; p.A333V; 20:62909862-62909862	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1272G>A; p.A424A; 20:62907249-62907249	thyroid	other; neoplasm	Substitution - coding silent
c.5316G>A; p.P1772P; 20:62880640-62880640	central_nervous_system; brain	glioma	Substitution - coding silent
c.4167G>T; p.E1389D; 20:62881789-62881789	breast	carcinoma	Substitution - Missense
c.5969G>A; p.G1990D; 20:62879987-62879987	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1425delA; p.E476fs*4; 20:62906050-62906050	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1425delA; p.E476fs*4; 20:62906050-62906050	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4988C>T; p.P1663L; 20:62880968-62880968	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.5199C>T; p.T1733T; 20:62880757-62880757	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1511C>T; p.S504L; 20:62905964-62905964	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4749A>T; p.A1583A; 20:62881207-62881207	lung	carcinoma; adenocarcinoma	Substitution - coding silent

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]