| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 11337 |
Name | GABARAP |
Synonymous | GABA(A) receptor-associated protein;GABARAP;GABA(A) receptor-associated protein |
Definition | gamma-aminobutyric acid receptor-associated protein |
Position | 17p13.1 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
 |
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Loss of Function mutations compare to missense mutations | Top |
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| The ratio of the loss-of-function mutations over missense mutations is 0.00. |
The copy number variations for various cancers | Top |
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The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
|
Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.3G>A; p.M1I; 17:7242328-7242328 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.210C>T; p.L70L; 17:7241420-7241420 |
skin | malignant_melanoma | Substitution - coding silent |
c.300A>C; p.E100D; 17:7240908-7240908 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.43C>A; p.R15S; 17:7242288-7242288 |
liver | carcinoma | Substitution - Missense |
c.49G>A; p.E17K; 17:7242282-7242282 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.80A>G; p.D27G; 17:7242251-7242251 |
breast | carcinoma | Substitution - Missense |
c.318C>T; p.Y106Y; 17:7240890-7240890 |
breast | carcinoma | Substitution - coding silent |
c.186C>T; p.F62F; 17:7241444-7241444 |
breast | carcinoma | Substitution - coding silent |
c.238G>A; p.V80I; 17:7241392-7241392 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.81_82CC>TT; p.R28W; 17:7242249-7242250 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.30G>A; p.P10P; 17:7242301-7242301 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.333C>T; p.D111D; 17:7240875-7240875 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.286C>A; p.Q96K; 17:7241344-7241344 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |