Entrez Gene

Basic Information
Gene ID	1755
Name	DMBT1
Synonymous	deleted in malignant brain tumors 1;DMBT1;deleted in malignant brain tumors 1
Definition	SAG\|deleted in malignant brain tumors 1 protein\|glycoprotein 340\|gp-340\|hensin\|salivary agglutinin\|surfactant pulmonary-associated D-binding protein
Position	10q26.13
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.07.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.4990G>A; p.V1664M; 10:122621149-122621149	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7079G>C; p.C2360S; 10:122643235-122643235	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2340G>A; p.T780T; 10:122592435-122592435	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.6455T>C; p.V2152A; 10:122637212-122637212	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.7126C>T; p.R2376*; 10:122643282-122643282	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4928T>G; p.V1643G; 10:122621087-122621087	breast	carcinoma	Substitution - Missense
c.2147C>A; p.S716*; 10:122591488-122591488	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Nonsense
c.2147C>A; p.S716*; 10:122591488-122591488	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2723C>G; p.A908G; 10:122582759-122582759	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5714G>T; p.G1905V; 10:122631036-122631036	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6501G>C; p.T2167T; 10:122637258-122637258	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5282-1G>A; p.?; 10:122629839-122629839	skin	malignant_melanoma	Unknown
c.502G>A; p.D168N; 10:122576617-122576617	skin	malignant_melanoma	Substitution - Missense
c.454C>T; p.P152S; 10:122576569-122576569	skin	malignant_melanoma	Substitution - Missense
c.7094G>A; p.C2365Y; 10:122643250-122643250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6741A>G; p.E2247E; 10:122640225-122640225	skin	malignant_melanoma	Substitution - coding silent
c.491T>C; p.I164T; 10:122576606-122576606	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5429A>T; p.N1810I; 10:122629987-122629987	skin	malignant_melanoma	Substitution - Missense
c.7012C>T; p.R2338C; 10:122643168-122643168	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.870C>T; p.G290G; 10:122579768-122579768	breast	carcinoma	Substitution - coding silent
c.7012C>T; p.R2338C; 10:122643168-122643168	skin	malignant_melanoma	Substitution - Missense
c.367T>G; p.W123G; 10:122576482-122576482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.854G>A; p.G285E; 10:122579752-122579752	skin	malignant_melanoma	Substitution - Missense
c.7012C>T; p.R2338C; 10:122643168-122643168	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3038C>T; p.S1013F; 10:122598855-122598855	skin	malignant_melanoma	Substitution - Missense
c.367T>G; p.W123G; 10:122576482-122576482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5159C>T; p.P1720L; 10:122621318-122621318	skin	malignant_melanoma	Substitution - Missense
c.3038C>T; p.S1013F; 10:122598855-122598855	skin	malignant_melanoma	Substitution - Missense
c.7012C>T; p.R2338C; 10:122643168-122643168	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1012T>C; p.S338P; 10:122580874-122580874	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.7012C>T; p.R2338C; 10:122643168-122643168	skin	malignant_melanoma	Substitution - Missense
c.870C>T; p.G290G; 10:122579768-122579768	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.7002G>A; p.S2334S; 10:122643158-122643158	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6605C>T; p.S2202L; 10:122640089-122640089	urinary_tract; bladder	carcinoma	Substitution - Missense
c.7186G>A; p.V2396I; 10:122643342-122643342	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4763_4764insC; p.H1590fs*13; 10:122618275-122618276	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.6222C>T; p.S2074S; 10:122636051-122636051	skin	malignant_melanoma	Substitution - coding silent
c.200C>T; p.S67F; 10:122572326-122572326	skin	malignant_melanoma	Substitution - Missense
c.3401G>A; p.R1134Q; 10:122601854-122601854	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.200C>T; p.S67F; 10:122572326-122572326	skin	malignant_melanoma	Substitution - Missense
c.6765G>A; p.V2255V; 10:122640249-122640249	skin	malignant_melanoma	Substitution - coding silent
c.4972C>T; p.R1658*; 10:122621131-122621131	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4972C>T; p.R1658*; 10:122621131-122621131	skin	malignant_melanoma	Substitution - Nonsense
c.6007A>C; p.N2003H; 10:122632887-122632887	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7200C>T; p.I2400I; 10:122643356-122643356	skin	malignant_melanoma	Substitution - coding silent
c.3172G>T; p.D1058Y; 10:122598989-122598989	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4972C>T; p.R1658*; 10:122621131-122621131	skin	malignant_melanoma	Substitution - Nonsense
c.2168C>T; p.S723L; 10:122591509-122591509	breast	carcinoma	Substitution - Missense
c.4314T>G; p.G1438G; 10:122606052-122606052	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2168C>T; p.S723L; 10:122591509-122591509	skin	malignant_melanoma	Substitution - Missense
c.6461C>T; p.S2154F; 10:122637218-122637218	skin	malignant_melanoma	Substitution - Missense
c.1640C>T; p.A547V; 10:122586240-122586240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5081G>A; p.R1694Q; 10:122621240-122621240	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1020G>A; p.P340P; 10:122580882-122580882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1020G>A; p.P340P; 10:122580882-122580882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.7143G>A; p.R2381R; 10:122643299-122643299	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5081G>A; p.R1694Q; 10:122621240-122621240	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1020G>A; p.P340P; 10:122580882-122580882	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1579G>A; p.D527N; 10:122586179-122586179	skin	malignant_melanoma	Substitution - Missense
c.5949C>T; p.V1983V; 10:122631271-122631271	skin	malignant_melanoma	Substitution - coding silent
c.2233C>T; p.R745*; 10:122592328-122592328	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1579G>T; p.D527Y; 10:122586179-122586179	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6868C>T; p.H2290Y; 10:122640352-122640352	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4973G>A; p.R1658Q; 10:122621132-122621132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1463C>T; p.S488F; 10:122586063-122586063	skin	malignant_melanoma	Substitution - Missense
c.6815G>A; p.R2272H; 10:122640299-122640299	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.697G>A; p.A233T; 10:122579595-122579595	skin	malignant_melanoma	Substitution - Missense
c.194C>T; p.P65L; 10:122572320-122572320	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5903G>T; p.R1968L; 10:122631225-122631225	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4548C>G; p.D1516E; 10:122618060-122618060	breast	carcinoma	Substitution - Missense
c.5783G>A; p.G1928E; 10:122631105-122631105	skin	malignant_melanoma	Substitution - Missense
c.2395G>A; p.D799N; 10:122592490-122592490	skin	malignant_melanoma	Substitution - Missense
c.6588C>T; p.F2196F; 10:122640072-122640072	skin	malignant_melanoma	Substitution - coding silent
c.2395G>A; p.D799N; 10:122592490-122592490	skin	malignant_melanoma	Substitution - Missense
c.1639G>A; p.A547T; 10:122586239-122586239	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6868C>A; p.H2290N; 10:122640352-122640352	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.7145C>T; p.S2382L; 10:122643301-122643301	skin	malignant_melanoma	Substitution - Missense
c.7145C>T; p.S2382L; 10:122643301-122643301	skin	malignant_melanoma	Substitution - Missense
c.403G>T; p.D135Y; 10:122576518-122576518	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.487C>A; p.P163T; 10:122576602-122576602	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.4954C>A; p.R1652R; 10:122621113-122621113	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.505G>T; p.V169L; 10:122576620-122576620	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3018G>A; p.V1006V; 10:122598835-122598835	skin	malignant_melanoma	Substitution - coding silent
c.6193G>A; p.E2065K; 10:122636022-122636022	skin	malignant_melanoma	Substitution - Missense
c.2944G>A; p.A982T; 10:122598000-122598000	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5874G>A; p.T1958T; 10:122631196-122631196	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3527G>A; p.R1176Q; 10:122601980-122601980	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5092G>T; p.G1698C; 10:122621251-122621251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.523G>A; p.E175K; 10:122576638-122576638	skin	malignant_melanoma	Substitution - Missense
c.3030C>G; p.Y1010*; 10:122598847-122598847	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.5906G>A; p.G1969D; 10:122631228-122631228	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.508C>T; p.R170C; 10:122576623-122576623	thyroid	carcinoma	Substitution - Missense
c.523G>A; p.E175K; 10:122576638-122576638	skin	malignant_melanoma	Substitution - Missense
c.4616A>T; p.D1539V; 10:122618128-122618128	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4300C>T; p.R1434W; 10:122606038-122606038	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5128T>G; p.S1710A; 10:122621287-122621287	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4300C>T; p.R1434W; 10:122606038-122606038	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5128T>G; p.S1710A; 10:122621287-122621287	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2196C>A; p.T732T; 10:122592291-122592291	breast	carcinoma	Substitution - coding silent
c.6814C>G; p.R2272G; 10:122640298-122640298	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.5460T>G; p.S1820R; 10:122630312-122630312	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1018C>A; p.P340T; 10:122580880-122580880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5926A>G; p.N1976D; 10:122631248-122631248	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.5926A>G; p.N1976D; 10:122631248-122631248	liver	carcinoma	Substitution - Missense
c.6814C>G; p.R2272G; 10:122640298-122640298	liver	carcinoma	Substitution - Missense
c.4581A>C; p.Q1527H; 10:122618093-122618093	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1946C>T; p.T649M; 10:122589106-122589106	central_nervous_system; brain	glioma	Substitution - Missense
c.771C>T; p.T257T; 10:122579669-122579669	ovary	other; neoplasm	Substitution - coding silent
c.2501T>C; p.V834A; 10:122593569-122593569	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.6115G>C; p.E2039Q; 10:122633295-122633295	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1807A>T; p.R603W; 10:122588967-122588967	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.6189T>A; p.Y2063*; 10:122636018-122636018	skin	malignant_melanoma	Substitution - Nonsense
c.3055G>A; p.D1019N; 10:122598872-122598872	skin	malignant_melanoma	Substitution - Missense
c.3055G>A; p.D1019N; 10:122598872-122598872	skin	malignant_melanoma	Substitution - Missense
c.3055G>A; p.D1019N; 10:122598872-122598872	skin	malignant_melanoma	Substitution - Missense
c.3055G>A; p.D1019N; 10:122598872-122598872	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.6971T>A; p.V2324E; 10:122643127-122643127	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1675G>A; p.D559N; 10:122586275-122586275	skin	malignant_melanoma	Substitution - Missense
c.1769G>A; p.G590D; 10:122586369-122586369	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6293G>A; p.R2098H; 10:122636122-122636122	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3483G>A; p.R1161R; 10:122601936-122601936	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3483G>A; p.R1161R; 10:122601936-122601936	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3481A>C; p.R1161R; 10:122601934-122601934	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2097C>T; p.V699V; 10:122589257-122589257	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6293G>A; p.R2098H; 10:122636122-122636122	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3483G>A; p.R1161R; 10:122601936-122601936	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.5805C>T; p.A1935A; 10:122631127-122631127	skin	malignant_melanoma	Substitution - coding silent
c.6621G>A; p.K2207K; 10:122640105-122640105	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2366G>C; p.G789A; 10:122592461-122592461	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2251C>A; p.R751R; 10:122592346-122592346	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2994A>C; p.G998G; 10:122598811-122598811	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1824T>A; p.G608G; 10:122588984-122588984	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1681G>A; p.V561M; 10:122586281-122586281	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1643G>A; p.R548Q; 10:122586243-122586243	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2108-2A>T; p.?; 10:122590663-122590663	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.161C>T; p.S54L; 10:122570911-122570911	kidney	other; neoplasm	Substitution - Missense
c.2388T>C; p.V796V; 10:122592483-122592483	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.7127G>A; p.R2376Q; 10:122643283-122643283	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.390C>T; p.S130S; 10:122576505-122576505	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.7127G>A; p.R2376Q; 10:122643283-122643283	skin	malignant_melanoma	Substitution - Missense
c.4282T>G; p.S1428A; 10:122606020-122606020	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5349T>C; p.P1783P; 10:122629907-122629907	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.6272C>T; p.S2091F; 10:122636101-122636101	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6788C>T; p.S2263L; 10:122640272-122640272	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6788C>T; p.S2263L; 10:122640272-122640272	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.755G>A; p.R252Q; 10:122579653-122579653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6788C>T; p.S2263L; 10:122640272-122640272	skin	malignant_melanoma	Substitution - Missense
c.2001T>A; p.D667E; 10:122589161-122589161	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2232C>T; p.G744G; 10:122592327-122592327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4368G>C; p.L1456L; 10:122606106-122606106	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5207G>A; p.G1736D; 10:122621366-122621366	skin	malignant_melanoma	Substitution - Missense
c.5017G>A; p.D1673N; 10:122621176-122621176	skin	malignant_melanoma	Substitution - Missense
c.7054C>T; p.R2352C; 10:122643210-122643210	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3536A>C; p.Q1179P; 10:122601989-122601989	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3182G>T; p.R1061L; 10:122598999-122598999	urinary_tract; bladder	carcinoma	Substitution - Missense
c.5691G>A; p.G1897G; 10:122631013-122631013	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2430G>C; p.W810C; 10:122592525-122592525	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.458G>A; p.G153E; 10:122576573-122576573	skin	malignant_melanoma	Substitution - Missense
c.6744C>T; p.V2248V; 10:122640228-122640228	skin	malignant_melanoma	Substitution - coding silent
c.1569G>A; p.W523*; 10:122586169-122586169	skin	malignant_melanoma	Substitution - Nonsense
c.1679A>G; p.D560G; 10:122586279-122586279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2957-1G>A; p.?; 10:122598773-122598773	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2956+6T>C; p.?; 10:122598018-122598018	liver	carcinoma	Unknown
c.2956+6T>C; p.?; 10:122598018-122598018	liver	carcinoma	Unknown
c.4489C>T; p.R1497C; 10:122617245-122617245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6193G>T; p.E2065*; 10:122636022-122636022	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3250C>T; p.H1084Y; 10:122599067-122599067	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3250C>T; p.H1084Y; 10:122599067-122599067	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3250C>T; p.H1084Y; 10:122599067-122599067	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3250C>T; p.H1084Y; 10:122599067-122599067	thyroid	other; neoplasm	Substitution - Missense
c.4599G>T; p.V1533V; 10:122618111-122618111	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2303A>G; p.N768S; 10:122592398-122592398	liver	carcinoma	Substitution - Missense
c.3524C>A; p.A1175D; 10:122601977-122601977	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3249C>T; p.G1083G; 10:122599066-122599066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.885C>G; p.P295P; 10:122579783-122579783	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3251A>G; p.H1084R; 10:122599068-122599068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4290A>C; p.P1430P; 10:122606028-122606028	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5933G>A; p.R1978H; 10:122631255-122631255	breast	carcinoma	Substitution - Missense
c.6021C>T; p.S2007S; 10:122633201-122633201	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5692C>T; p.R1898C; 10:122631014-122631014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2164C>T; p.P722S; 10:122591505-122591505	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3525C>A; p.A1175A; 10:122601978-122601978	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.957C>T; p.L319L; 10:122579855-122579855	NS	malignant_melanoma	Substitution - coding silent
c.957C>T; p.L319L; 10:122579855-122579855	NS	malignant_melanoma	Substitution - coding silent
c.5896C>T; p.R1966W; 10:122631218-122631218	central_nervous_system; brain	glioma	Substitution - Missense
c.304C>T; p.L102L; 10:122576419-122576419	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5549C>G; p.S1850C; 10:122630401-122630401	breast	carcinoma	Substitution - Missense
c.3066G>A; p.W1022*; 10:122598883-122598883	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.4694G>T; p.G1565V; 10:122618206-122618206	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3066G>A; p.W1022*; 10:122598883-122598883	skin	malignant_melanoma	Substitution - Nonsense
c.5850G>T; p.L1950L; 10:122631172-122631172	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.710T>G; p.V237G; 10:122579608-122579608	breast	carcinoma	Substitution - Missense
c.4487C>G; p.S1496C; 10:122617243-122617243	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.5071G>C; p.G1691R; 10:122621230-122621230	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5977C>G; p.P1993A; 10:122631872-122631872	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4662G>T; p.W1554C; 10:122618174-122618174	breast	carcinoma	Substitution - Missense
c.1765G>A; p.A589T; 10:122586365-122586365	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1765G>A; p.A589T; 10:122586365-122586365	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3238C>A; p.H1080N; 10:122599055-122599055	skin	malignant_melanoma	Substitution - Missense
c.1765G>A; p.A589T; 10:122586365-122586365	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.331T>G; p.C111G; 10:122576446-122576446	breast	carcinoma	Substitution - Missense
c.4912T>G; p.L1638V; 10:122621071-122621071	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1590G>T; p.V530V; 10:122586190-122586190	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3205C>T; p.L1069L; 10:122599022-122599022	skin	malignant_melanoma	Substitution - coding silent
c.3522T>A; p.N1174K; 10:122601975-122601975	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5932C>T; p.R1978C; 10:122631254-122631254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1678G>A; p.D560N; 10:122586278-122586278	skin	malignant_melanoma	Substitution - Missense
c.5932C>T; p.R1978C; 10:122631254-122631254	skin	malignant_melanoma	Substitution - Missense
c.1720C>T; p.P574S; 10:122586320-122586320	skin	malignant_melanoma	Substitution - Missense
c.7018G>T; p.A2340S; 10:122643174-122643174	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.91+10T>C; p.?; 10:122566006-122566006	liver	carcinoma	Unknown
c.5932C>T; p.R1978C; 10:122631254-122631254	skin	malignant_melanoma	Substitution - Missense
c.91+10T>C; p.?; 10:122566006-122566006	liver	carcinoma	Unknown
c.5932C>T; p.R1978C; 10:122631254-122631254	skin	malignant_melanoma	Substitution - Missense
c.2351G>A; p.G784E; 10:122592446-122592446	skin	malignant_melanoma	Substitution - Missense
c.5688C>T; p.A1896A; 10:122631010-122631010	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4617C>T; p.D1539D; 10:122618129-122618129	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1028G>C; p.S343T; 10:122580890-122580890	thyroid	other; neoplasm	Substitution - Missense
c.1706A>T; p.Y569F; 10:122586306-122586306	skin	malignant_melanoma	Substitution - Missense
c.2351G>A; p.G784E; 10:122592446-122592446	skin	malignant_melanoma	Substitution - Missense
c.6636_6637CC>TT; p.R2213C; 10:122640120-122640121	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1028G>C; p.S343T; 10:122580890-122580890	thyroid	other; neoplasm	Substitution - Missense
c.4996G>A; p.D1666N; 10:122621155-122621155	skin	malignant_melanoma	Substitution - Missense
c.4490G>A; p.R1497H; 10:122617246-122617246	thyroid	other; neoplasm	Substitution - Missense
c.964A>G; p.N322D; 10:122579862-122579862	urinary_tract; bladder	carcinoma	Substitution - Missense
c.964A>G; p.N322D; 10:122579862-122579862	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3165T>G; p.I1055M; 10:122598982-122598982	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4996G>A; p.D1666N; 10:122621155-122621155	skin	malignant_melanoma	Substitution - Missense
c.5636G>A; p.S1879N; 10:122630488-122630488	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4878C>T; p.N1626N; 10:122620272-122620272	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5428A>G; p.N1810D; 10:122629986-122629986	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.3517G>A; p.G1173R; 10:122601970-122601970	skin	malignant_melanoma	Substitution - Missense
c.2281A>T; p.S761C; 10:122592376-122592376	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.284-2A>G; p.?; 10:122576397-122576397	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.3148C>A; p.Q1050K; 10:122598965-122598965	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3511G>A; p.A1171T; 10:122601964-122601964	skin	malignant_melanoma	Substitution - Missense
c.5848C>T; p.L1950L; 10:122631170-122631170	skin	malignant_melanoma	Substitution - coding silent
c.5902C>T; p.R1968*; 10:122631224-122631224	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.3527G>T; p.R1176L; 10:122601980-122601980	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2015C>T; p.S672L; 10:122589175-122589175	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5902C>T; p.R1968*; 10:122631224-122631224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4130G>C; p.S1377T; 10:122605868-122605868	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.6055T>C; p.F2019L; 10:122633235-122633235	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.725G>T; p.R242M; 10:122579623-122579623	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.642T>G; p.S214R; 10:122578722-122578722	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.6411C>T; p.S2137S; 10:122637168-122637168	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6105G>A; p.V2035V; 10:122633285-122633285	pancreas	carcinoma	Substitution - coding silent
c.6062G>T; p.S2021I; 10:122633242-122633242	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4985G>A; p.G1662E; 10:122621144-122621144	skin	malignant_melanoma	Substitution - Missense
c.1535G>A; p.R512Q; 10:122586135-122586135	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.612C>A; p.A204A; 10:122577815-122577815	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1859G>A; p.R620Q; 10:122589019-122589019	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2339C>T; p.T780M; 10:122592434-122592434	pancreas	carcinoma	Substitution - Missense
c.5415C>T; p.N1805N; 10:122629973-122629973	skin	malignant_melanoma	Substitution - coding silent
c.5092G>A; p.G1698S; 10:122621251-122621251	skin	malignant_melanoma	Substitution - Missense
c.3196G>A; p.E1066K; 10:122599013-122599013	skin	malignant_melanoma	Substitution - Missense
c.2259C>A; p.S753S; 10:122592354-122592354	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.2525G>C; p.S842T; 10:122593593-122593593	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6461C>A; p.S2154Y; 10:122637218-122637218	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5288C>T; p.S1763F; 10:122629846-122629846	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6406G>A; p.V2136M; 10:122637163-122637163	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6406G>A; p.V2136M; 10:122637163-122637163	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4743C>G; p.H1581Q; 10:122618255-122618255	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6406G>A; p.V2136M; 10:122637163-122637163	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.834C>A; p.G278G; 10:122579732-122579732	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.6133C>A; p.R2045S; 10:122633313-122633313	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.2937C>G; p.T979T; 10:122597993-122597993	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2630T>G; p.V877G; 10:122582666-122582666	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.4361C>T; p.S1454F; 10:122606099-122606099	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3121T>A; p.S1041T; 10:122598938-122598938	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1801G>A; p.A601T; 10:122588961-122588961	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7235C>T; p.P2412L; 10:122643391-122643391	skin	malignant_melanoma	Substitution - Missense
c.512G>A; p.C171Y; 10:122576627-122576627	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3310+3G>A; p.?; 10:122600096-122600096	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.6838C>A; p.Q2280K; 10:122640322-122640322	thyroid	other; neoplasm	Substitution - Missense
c.1044G>A; p.P348P; 10:122581803-122581803	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2489T>G; p.V830G; 10:122592584-122592584	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5194C>A; p.H1732N; 10:122621353-122621353	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5194C>A; p.H1732N; 10:122621353-122621353	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5194C>A; p.H1732N; 10:122621353-122621353	skin	malignant_melanoma	Substitution - Missense
c.5194C>A; p.H1732N; 10:122621353-122621353	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5194C>A; p.H1732N; 10:122621353-122621353	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1033+2T>C; p.?; 10:122580897-122580897	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.5520C>A; p.I1840I; 10:122630372-122630372	liver	carcinoma	Substitution - coding silent
c.5195A>G; p.H1732R; 10:122621354-122621354	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5195A>G; p.H1732R; 10:122621354-122621354	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5195A>G; p.H1732R; 10:122621354-122621354	skin	malignant_melanoma	Substitution - Missense
c.4979C>T; p.S1660F; 10:122621138-122621138	urinary_tract; bladder	carcinoma	Substitution - Missense
c.5195A>G; p.H1732R; 10:122621354-122621354	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5195A>G; p.H1732R; 10:122621354-122621354	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5881A>C; p.T1961P; 10:122631203-122631203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5520C>A; p.I1840I; 10:122630372-122630372	liver	carcinoma	Substitution - coding silent
c.855A>G; p.G285G; 10:122579753-122579753	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5903G>A; p.R1968Q; 10:122631225-122631225	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.7210_7211insC; p.R2407fs*>8; 10:122643366-122643367	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.993C>T; p.V331V; 10:122579891-122579891	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3131G>A; p.G1044E; 10:122598948-122598948	skin	malignant_melanoma	Substitution - Missense
c.3131G>A; p.G1044E; 10:122598948-122598948	skin	malignant_melanoma	Substitution - Missense
c.6901A>G; p.T2301A; 10:122640385-122640385	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.6449A>G; p.D2150G; 10:122637206-122637206	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5897G>A; p.R1966Q; 10:122631219-122631219	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.6073C>T; p.P2025S; 10:122633253-122633253	skin	malignant_melanoma	Substitution - Missense
c.488C>T; p.P163L; 10:122576603-122576603	skin	malignant_melanoma	Substitution - Missense
c.2343G>C; p.S781S; 10:122592438-122592438	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.4744G>A; p.E1582K; 10:122618256-122618256	skin	malignant_melanoma	Substitution - Missense
c.6744C>A; p.V2248V; 10:122640228-122640228	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.5168G>A; p.G1723D; 10:122621327-122621327	skin	malignant_melanoma	Substitution - Missense
c.2476G>A; p.E826K; 10:122592571-122592571	skin	malignant_melanoma	Substitution - Missense
c.2402G>A; p.R801H; 10:122592497-122592497	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2402G>A; p.R801H; 10:122592497-122592497	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.5753A>T; p.Q1918L; 10:122631075-122631075	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.5638G>A; p.D1880N; 10:122630490-122630490	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1634G>A; p.G545E; 10:122586234-122586234	skin	malignant_melanoma	Substitution - Missense
c.1495G>A; p.G499R; 10:122586095-122586095	skin	malignant_melanoma	Substitution - Missense
c.3250C>A; p.H1084N; 10:122599067-122599067	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7185C>T; p.V2395V; 10:122643341-122643341	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2436C>A; p.C812*; 10:122592531-122592531	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.7185C>T; p.V2395V; 10:122643341-122643341	skin	malignant_melanoma	Substitution - coding silent
c.7185C>T; p.V2395V; 10:122643341-122643341	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.543delC; p.H183fs*52; 10:122576658-122576658	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2360G>A; p.R787Q; 10:122592455-122592455	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.640A>T; p.S214C; 10:122578720-122578720	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.6970G>A; p.V2324M; 10:122643126-122643126	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6970G>A; p.V2324M; 10:122643126-122643126	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6646G>A; p.V2216I; 10:122640130-122640130	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.751T>A; p.Y251N; 10:122579649-122579649	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1410G>A; p.T470T; 10:122584341-122584341	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4640G>T; p.C1547F; 10:122618152-122618152	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.5004C>T; p.S1668S; 10:122621163-122621163	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3293G>A; p.R1098Q; 10:122600076-122600076	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4804G>A; p.E1602K; 10:122618316-122618316	skin	malignant_melanoma	Substitution - Missense
c.3261C>T; p.D1087D; 10:122599078-122599078	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3261C>T; p.D1087D; 10:122599078-122599078	oesophagus	carcinoma	Substitution - coding silent
c.1759G>A; p.E587K; 10:122586359-122586359	skin	malignant_melanoma	Substitution - Missense
c.4678G>A; p.G1560R; 10:122618190-122618190	skin	malignant_melanoma	Substitution - Missense
c.7181A>G; p.D2394G; 10:122643337-122643337	skin	malignant_melanoma	Substitution - Missense
c.6235C>T; p.R2079*; 10:122636064-122636064	skin	malignant_melanoma	Substitution - Nonsense
c.2987T>G; p.V996G; 10:122598804-122598804	breast	carcinoma	Substitution - Missense
c.2513G>A; p.R838Q; 10:122593581-122593581	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.6282C>T; p.F2094F; 10:122636111-122636111	skin	malignant_melanoma	Substitution - coding silent
c.5427T>A; p.S1809R; 10:122629985-122629985	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.7223G>A; p.R2408Q; 10:122643379-122643379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7171G>A; p.E2391K; 10:122643327-122643327	skin	malignant_melanoma	Substitution - Missense
c.5116G>A; p.D1706N; 10:122621275-122621275	skin	malignant_melanoma	Substitution - Missense
c.4706G>T; p.G1569V; 10:122618218-122618218	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6215G>A; p.R2072H; 10:122636044-122636044	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.104C>T; p.P35L; 10:122570174-122570174	skin	malignant_melanoma	Substitution - Missense
c.6215G>A; p.R2072H; 10:122636044-122636044	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.958A>T; p.T320S; 10:122579856-122579856	urinary_tract; bladder	carcinoma	Substitution - Missense
c.6730C>T; p.Q2244*; 10:122640214-122640214	skin	malignant_melanoma	Substitution - Nonsense
c.4562G>A; p.R1521Q; 10:122618074-122618074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6287C>T; p.S2096F; 10:122636116-122636116	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3297A>G; p.P1099P; 10:122600080-122600080	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1028G>A; p.S343N; 10:122580890-122580890	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3032A>G; p.Q1011R; 10:122598849-122598849	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5810G>A; p.G1937E; 10:122631132-122631132	skin	malignant_melanoma	Substitution - Missense
c.5964C>T; p.N1988N; 10:122631859-122631859	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5157delC; p.H1721fs*24; 10:122621316-122621316	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3032A>G; p.Q1011R; 10:122598849-122598849	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3231G>A; p.W1077*; 10:122599048-122599048	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.6028G>A; p.G2010S; 10:122633208-122633208	skin	malignant_melanoma	Substitution - Missense
c.6020C>T; p.S2007F; 10:122633200-122633200	skin	malignant_melanoma	Substitution - Missense
c.1954C>T; p.P652S; 10:122589114-122589114	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4688A>G; p.Q1563R; 10:122618200-122618200	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4688A>G; p.Q1563R; 10:122618200-122618200	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.6962G>T; p.S2321I; 10:122640446-122640446	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6773C>T; p.S2258F; 10:122640257-122640257	skin	malignant_melanoma	Substitution - Missense
c.5303G>A; p.G1768D; 10:122629861-122629861	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6154G>A; p.D2052N; 10:122633334-122633334	pancreas	carcinoma	Substitution - Missense
c.6000C>T; p.T2000T; 10:122632880-122632880	skin	malignant_melanoma	Substitution - coding silent
c.6154G>A; p.D2052N; 10:122633334-122633334	skin	malignant_melanoma	Substitution - Missense
c.6773C>T; p.S2258F; 10:122640257-122640257	skin	malignant_melanoma	Substitution - Missense
c.7022G>A; p.R2341H; 10:122643178-122643178	pancreas	carcinoma	Substitution - Missense
c.7022G>A; p.R2341H; 10:122643178-122643178	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1658C>T; p.S553L; 10:122586258-122586258	skin	malignant_melanoma	Substitution - Missense
c.1730G>A; p.G577D; 10:122586330-122586330	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1730G>A; p.G577D; 10:122586330-122586330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4567G>A; p.E1523K; 10:122618079-122618079	skin	malignant_melanoma	Substitution - Missense
c.1730G>A; p.G577D; 10:122586330-122586330	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3005G>T; p.C1002F; 10:122598822-122598822	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2531-1G>T; p.?; 10:122594495-122594495	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3009G>A; p.Q1003Q; 10:122598826-122598826	skin	malignant_melanoma	Substitution - coding silent
c.1680C>T; p.D560D; 10:122586280-122586280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1680C>T; p.D560D; 10:122586280-122586280	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1680C>T; p.D560D; 10:122586280-122586280	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4562G>T; p.R1521L; 10:122618074-122618074	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.417C>T; p.V139V; 10:122576532-122576532	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6865C>T; p.L2289F; 10:122640349-122640349	skin	malignant_melanoma	Substitution - Missense
c.7215C>T; p.P2405P; 10:122643371-122643371	skin	malignant_melanoma	Substitution - coding silent
c.788G>T; p.W263L; 10:122579686-122579686	skin	malignant_melanoma	Substitution - Missense
c.146C>A; p.P49Q; 10:122570896-122570896	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.984C>G; p.D328E; 10:122579882-122579882	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1541C>T; p.S514F; 10:122586141-122586141	skin	malignant_melanoma	Substitution - Missense
c.6976G>A; p.D2326N; 10:122643132-122643132	skin	malignant_melanoma	Substitution - Missense
c.3283T>C; p.S1095P; 10:122600066-122600066	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6315C>T; p.I2105I; 10:122636144-122636144	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4854G>A; p.R1618R; 10:122619333-122619333	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3188C>G; p.S1063*; 10:122599005-122599005	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.3210G>A; p.W1070*; 10:122599027-122599027	skin	malignant_melanoma	Substitution - Nonsense
c.881G>A; p.G294E; 10:122579779-122579779	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.5935G>A; p.E1979K; 10:122631257-122631257	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1851C>T; p.V617V; 10:122589011-122589011	skin	malignant_melanoma	Substitution - coding silent
c.2971T>G; p.L991V; 10:122598788-122598788	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3288G>T; p.Q1096H; 10:122600071-122600071	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5389G>T; p.E1797*; 10:122629947-122629947	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1945A>G; p.T649A; 10:122589105-122589105	thyroid	other; neoplasm	Substitution - Missense
c.2950A>T; p.T984S; 10:122598006-122598006	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3235T>A; p.S1079T; 10:122599052-122599052	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2940G>A; p.L980L; 10:122597996-122597996	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5141C>T; p.S1714F; 10:122621300-122621300	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1565G>T; p.S522I; 10:122586165-122586165	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.5399C>G; p.S1800C; 10:122629957-122629957	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2124G>A; p.S708S; 10:122590681-122590681	skin	malignant_melanoma	Substitution - coding silent
c.5141C>T; p.S1714F; 10:122621300-122621300	liver	carcinoma	Substitution - Missense
c.1565G>T; p.S522I; 10:122586165-122586165	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.807T>C; p.N269N; 10:122579705-122579705	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.902T>C; p.V301A; 10:122579800-122579800	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5197G>A; p.E1733K; 10:122621356-122621356	skin	malignant_melanoma	Substitution - Missense
c.7211delC; p.P2406fs*>8; 10:122643367-122643367	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7211delC; p.P2406fs*>8; 10:122643367-122643367	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5197G>A; p.E1733K; 10:122621356-122621356	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5197G>A; p.E1733K; 10:122621356-122621356	skin	malignant_melanoma	Substitution - Missense
c.7211delC; p.P2406fs*>8; 10:122643367-122643367	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5197G>A; p.E1733K; 10:122621356-122621356	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.7211delC; p.P2406fs*>8; 10:122643367-122643367	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.689C>T; p.S230F; 10:122579587-122579587	skin	malignant_melanoma	Substitution - Missense
c.2011T>A; p.C671S; 10:122589171-122589171	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1528C>T; p.L510L; 10:122586128-122586128	liver	carcinoma	Substitution - coding silent
c.3037T>G; p.S1013A; 10:122598854-122598854	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.708G>A; p.L236L; 10:122579606-122579606	skin	malignant_melanoma	Substitution - coding silent
c.5766G>A; p.V1922V; 10:122631088-122631088	skin	malignant_melanoma	Substitution - coding silent
c.5854G>A; p.D1952N; 10:122631176-122631176	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2152A>G; p.I718V; 10:122591493-122591493	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1528C>T; p.L510L; 10:122586128-122586128	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.5760T>G; p.A1920A; 10:122631082-122631082	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.772G>A; p.V258M; 10:122579670-122579670	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5579G>A; p.R1860Q; 10:122630431-122630431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5579G>A; p.R1860Q; 10:122630431-122630431	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3087C>G; p.V1029V; 10:122598904-122598904	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.6762C>T; p.D2254D; 10:122640246-122640246	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.769A>C; p.T257P; 10:122579667-122579667	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2382C>T; p.P794P; 10:122592477-122592477	skin	malignant_melanoma	Substitution - coding silent
c.5080C>T; p.R1694W; 10:122621239-122621239	breast	carcinoma	Substitution - Missense
c.3087C>G; p.V1029V; 10:122598904-122598904	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.6762C>T; p.D2254D; 10:122640246-122640246	skin	malignant_melanoma	Substitution - coding silent
c.3087C>G; p.V1029V; 10:122598904-122598904	thyroid	other; neoplasm	Substitution - coding silent
c.3087C>G; p.V1029V; 10:122598904-122598904	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5579G>A; p.R1860Q; 10:122630431-122630431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5080C>T; p.R1694W; 10:122621239-122621239	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1655G>T; p.G552V; 10:122586255-122586255	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5845A>G; p.T1949A; 10:122631167-122631167	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.939C>G; p.C313W; 10:122579837-122579837	bone; rib	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.6763G>A; p.V2255M; 10:122640247-122640247	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4955G>A; p.R1652Q; 10:122621114-122621114	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6770T>C; p.I2257T; 10:122640254-122640254	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4948C>T; p.R1650*; 10:122621107-122621107	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.3110G>A; p.G1037D; 10:122598927-122598927	liver	carcinoma	Substitution - Missense
c.4780C>A; p.L1594I; 10:122618292-122618292	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1704C>T; p.S568S; 10:122586304-122586304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1876G>A; p.V626M; 10:122589036-122589036	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4781T>A; p.L1594H; 10:122618293-122618293	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1066+8A>C; p.?; 10:122581833-122581833	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.5520C>T; p.I1840I; 10:122630372-122630372	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.6687G>A; p.M2229I; 10:122640171-122640171	pancreas	carcinoma	Substitution - Missense
c.6269C>T; p.S2090F; 10:122636098-122636098	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.283+1G>A; p.?; 10:122573763-122573763	lung; right_lower_lobe	carcinoma; adenocarcinoma	Unknown
c.3117C>T; p.A1039A; 10:122598934-122598934	skin	malignant_melanoma	Substitution - coding silent
c.253G>T; p.E85*; 10:122573732-122573732	oesophagus	carcinoma	Substitution - Nonsense
c.6988G>A; p.G2330R; 10:122643144-122643144	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3489G>T; p.L1163L; 10:122601942-122601942	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2913T>G; p.S971R; 10:122597050-122597050	thyroid	other; neoplasm	Substitution - Missense
c.3146G>A; p.G1049D; 10:122598963-122598963	skin	malignant_melanoma	Substitution - Missense
c.4757G>T; p.W1586L; 10:122618269-122618269	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3146G>A; p.G1049D; 10:122598963-122598963	skin	malignant_melanoma	Substitution - Missense
c.2377G>A; p.G793R; 10:122592472-122592472	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3518G>A; p.G1173E; 10:122601971-122601971	skin	malignant_melanoma	Substitution - Missense
c.6490C>A; p.P2164T; 10:122637247-122637247	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2913T>G; p.S971R; 10:122597050-122597050	thyroid	other; neoplasm	Substitution - Missense
c.6289A>C; p.I2097L; 10:122636118-122636118	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.905G>A; p.R302H; 10:122579803-122579803	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.7013G>A; p.R2338H; 10:122643169-122643169	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1552G>A; p.V518M; 10:122586152-122586152	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1901A>G; p.N634S; 10:122589061-122589061	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.162G>A; p.S54S; 10:122570912-122570912	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5693G>A; p.R1898H; 10:122631015-122631015	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.195G>A; p.P65P; 10:122572321-122572321	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5389G>C; p.E1797Q; 10:122629947-122629947	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6221C>T; p.S2074F; 10:122636050-122636050	skin	malignant_melanoma	Substitution - Missense
c.1470C>T; p.S490S; 10:122586070-122586070	skin	malignant_melanoma	Substitution - coding silent
c.919G>A; p.E307K; 10:122579817-122579817	skin	malignant_melanoma	Substitution - Missense
c.4605T>C; p.D1535D; 10:122618117-122618117	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2514G>A; p.R838R; 10:122593582-122593582	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.7033A>G; p.R2345G; 10:122643189-122643189	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.6236G>A; p.R2079Q; 10:122636065-122636065	skin	malignant_melanoma	Substitution - Missense
c.3594G>C; p.L1198L; 10:122602047-122602047	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1452G>A; p.S484S; 10:122585302-122585302	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.247C>T; p.P83S; 10:122573726-122573726	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.607G>A; p.A203T; 10:122576722-122576722	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2512C>T; p.R838W; 10:122593580-122593580	pancreas	carcinoma	Substitution - Missense
c.6085C>T; p.P2029S; 10:122633265-122633265	skin	malignant_melanoma	Substitution - Missense
c.5539A>G; p.I1847V; 10:122630391-122630391	skin	malignant_melanoma	Substitution - Missense
c.4633G>T; p.V1545L; 10:122618145-122618145	large_intestine; caecum	adenoma	Substitution - Missense
c.6573C>T; p.I2191I; 10:122640057-122640057	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.7024T>C; p.F2342L; 10:122643180-122643180	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.732A>G; p.R244R; 10:122579630-122579630	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.278C>A; p.A93E; 10:122573757-122573757	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.473G>T; p.G158V; 10:122576588-122576588	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.473G>T; p.G158V; 10:122576588-122576588	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1003+9T>A; p.?; 10:122579910-122579910	ovary	other; neoplasm	Unknown
c.1826A>G; p.D609G; 10:122588986-122588986	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3305G>C; p.S1102T; 10:122600088-122600088	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787T>C; p.W263R; 10:122579685-122579685	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6201C>T; p.F2067F; 10:122636030-122636030	skin	malignant_melanoma	Substitution - coding silent
c.3292C>T; p.R1098W; 10:122600075-122600075	pancreas	carcinoma	Substitution - Missense
c.6828G>A; p.V2276V; 10:122640312-122640312	skin	malignant_melanoma	Substitution - coding silent
c.6201C>T; p.F2067F; 10:122636030-122636030	skin	malignant_melanoma	Substitution - coding silent
c.3122C>T; p.S1041L; 10:122598939-122598939	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.6201C>T; p.F2067F; 10:122636030-122636030	skin	malignant_melanoma	Substitution - coding silent
c.143C>T; p.S48F; 10:122570893-122570893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2526T>C; p.S842S; 10:122593594-122593594	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.721G>A; p.D241N; 10:122579619-122579619	skin	malignant_melanoma	Substitution - Missense
c.4678G>T; p.G1560*; 10:122618190-122618190	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4488T>G; p.S1496S; 10:122617244-122617244	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.6867C>T; p.L2289L; 10:122640351-122640351	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5791C>T; p.R1931C; 10:122631113-122631113	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.6503C>G; p.P2168R; 10:122637260-122637260	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.6818C>T; p.P2273L; 10:122640302-122640302	skin	malignant_melanoma	Substitution - Missense
c.7027C>T; p.R2343W; 10:122643183-122643183	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.6909G>A; p.V2303V; 10:122640393-122640393	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.898G>A; p.D300N; 10:122579796-122579796	skin	malignant_melanoma	Substitution - Missense
c.7116C>A; p.S2372S; 10:122643272-122643272	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.5066C>T; p.A1689V; 10:122621225-122621225	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2215A>G; p.S739G; 10:122592310-122592310	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.863A>G; p.Q288R; 10:122579761-122579761	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.5798T>C; p.V1933A; 10:122631120-122631120	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5060T>G; p.M1687R; 10:122621219-122621219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1803C>G; p.A601A; 10:122588963-122588963	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.4540G>A; p.G1514R; 10:122618052-122618052	skin	malignant_melanoma	Substitution - Missense
c.1477G>T; p.A493S; 10:122586077-122586077	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6817C>G; p.P2273A; 10:122640301-122640301	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.3463G>A; p.D1155N; 10:122601916-122601916	skin	malignant_melanoma	Substitution - Missense
c.730C>T; p.R244*; 10:122579628-122579628	skin	malignant_melanoma	Substitution - Nonsense
c.6076G>A; p.G2026R; 10:122633256-122633256	skin	malignant_melanoma	Substitution - Missense
c.5060T>G; p.M1687R; 10:122621219-122621219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.4677A>T; p.P1559P; 10:122618189-122618189	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1030C>A; p.P344T; 10:122580892-122580892	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1922G>A; p.R641K; 10:122589082-122589082	skin	malignant_melanoma	Substitution - Missense
c.5871G>A; p.G1957G; 10:122631193-122631193	skin	malignant_melanoma	Substitution - coding silent
c.810G>A; p.V270V; 10:122579708-122579708	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.766G>T; p.G256C; 10:122579664-122579664	ovary	other; neoplasm	Substitution - Missense
c.1526T>C; p.V509A; 10:122586126-122586126	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.741G>A; p.V247V; 10:122579639-122579639	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1020G>T; p.P340P; 10:122580882-122580882	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3303T>C; p.P1101P; 10:122600086-122600086	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3227G>A; p.G1076D; 10:122599044-122599044	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1750G>C; p.G584R; 10:122586350-122586350	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1803C>T; p.A601A; 10:122588963-122588963	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.6574G>A; p.D2192N; 10:122640058-122640058	skin	malignant_melanoma	Substitution - Missense
c.4578C>A; p.Y1526*; 10:122618090-122618090	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2343G>A; p.S781S; 10:122592438-122592438	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.5792G>A; p.R1931H; 10:122631114-122631114	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6074C>T; p.P2025L; 10:122633254-122633254	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3014G>A; p.R1005Q; 10:122598831-122598831	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5424C>A; p.F1808L; 10:122629982-122629982	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.7213C>T; p.P2405S; 10:122643369-122643369	skin	malignant_melanoma	Substitution - Missense
c.2953G>A; p.V985I; 10:122598009-122598009	central_nervous_system; brain	glioma	Substitution - Missense
c.6078G>A; p.G2026G; 10:122633258-122633258	skin	malignant_melanoma	Substitution - coding silent
c.2966C>T; p.S989F; 10:122598783-122598783	skin	malignant_melanoma	Substitution - Missense
c.6805G>A; p.V2269M; 10:122640289-122640289	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5688C>A; p.A1896A; 10:122631010-122631010	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2415C>A; p.H805Q; 10:122592510-122592510	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2182G>C; p.E728Q; 10:122592277-122592277	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2402G>T; p.R801L; 10:122592497-122592497	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.789G>A; p.W263*; 10:122579687-122579687	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.145C>T; p.P49S; 10:122570895-122570895	skin	malignant_melanoma	Substitution - Missense
c.7115C>T; p.S2372F; 10:122643271-122643271	skin	malignant_melanoma	Substitution - Missense
c.1764C>T; p.D588D; 10:122586364-122586364	breast	carcinoma	Substitution - coding silent
c.5151G>A; p.W1717*; 10:122621310-122621310	skin	malignant_melanoma	Substitution - Nonsense
c.2132G>A; p.R711K; 10:122590689-122590689	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.5244G>A; p.T1748T; 10:122625299-122625299	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5243_5244insC; p.T1749fs*43; 10:122625298-122625299	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.1014C>A; p.S338S; 10:122580876-122580876	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.4848_4849GC>TT; p.P1617S; 10:122619327-122619328	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1468T>A; p.S490T; 10:122586068-122586068	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.7183G>A; p.V2395I; 10:122643339-122643339	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.6090C>A; p.N2030K; 10:122633270-122633270	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.6206G>T; p.G2069V; 10:122636035-122636035	liver	carcinoma	Substitution - Missense
c.1905T>C; p.D635D; 10:122589065-122589065	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4143G>A; p.R1381R; 10:122605881-122605881	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.7146G>A; p.S2382S; 10:122643302-122643302	skin	malignant_melanoma	Substitution - coding silent
c.7146G>A; p.S2382S; 10:122643302-122643302	skin	malignant_melanoma	Substitution - coding silent
c.7146G>A; p.S2382S; 10:122643302-122643302	skin	malignant_melanoma	Substitution - coding silent
c.4749T>G; p.S1583S; 10:122618261-122618261	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2516C>T; p.P839L; 10:122593584-122593584	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3306T>C; p.S1102S; 10:122600089-122600089	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3597G>A; p.W1199*; 10:122602050-122602050	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1917C>T; p.V639V; 10:122589077-122589077	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.5064G>A; p.S1688S; 10:122621223-122621223	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1917C>T; p.V639V; 10:122589077-122589077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4797C>T; p.G1599G; 10:122618309-122618309	pancreas	carcinoma	Substitution - coding silent
c.6947A>T; p.Y2316F; 10:122640431-122640431	urinary_tract; bladder	carcinoma	Substitution - Missense
c.103C>T; p.P35S; 10:122570173-122570173	skin	malignant_melanoma	Substitution - Missense
c.3492C>T; p.G1164G; 10:122601945-122601945	skin	malignant_melanoma	Substitution - coding silent
c.3526C>T; p.R1176W; 10:122601979-122601979	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.5602A>T; p.T1868S; 10:122630454-122630454	skin	malignant_melanoma	Substitution - Missense
c.6297C>T; p.F2099F; 10:122636126-122636126	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2968A>T; p.S990C; 10:122598785-122598785	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3166G>T; p.V1056F; 10:122598983-122598983	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4943G>A; p.R1648K; 10:122621102-122621102	skin	malignant_melanoma	Substitution - Missense
c.7058T>A; p.F2353Y; 10:122643214-122643214	breast	carcinoma	Substitution - Missense
c.5425A>C; p.S1809R; 10:122629983-122629983	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.5449C>T; p.H1817Y; 10:122630301-122630301	skin	malignant_melanoma	Substitution - Missense
c.916C>A; p.H306N; 10:122579814-122579814	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]