Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

23336

Name

SYNM

Synonymous

synemin, intermediate filament protein;SYNM;synemin, intermediate filament protein

Definition

desmuslin|synemin|synemin alpha|synemin beta

Position

15q26.3

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.20.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.408G>A; p.R136R; 15:99105607-99105607

 thyroidother; neoplasmSubstitution - coding silent

c.3104G>A; p.R1035Q; 15:99131467-99131467

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.1547G>A; p.R516Q; 15:99129910-99129910

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1547G>A; p.R516Q; 15:99129910-99129910

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1414C>T; p.R472W; 15:99129777-99129777

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2649C>A; p.G883G; 15:99131012-99131012

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1547G>A; p.R516Q; 15:99129910-99129910

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1616A>G; p.E539G; 15:99129979-99129979

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.3197G>T; p.R1066L; 15:99131560-99131560

 pancreascarcinomaSubstitution - Missense

c.3197G>T; p.R1066L; 15:99131560-99131560

 pancreascarcinomaSubstitution - Missense

c.2511delC; p.H841fs*47; 15:99130874-99130874

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2404C>T; p.R802*; 15:99130767-99130767

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1252G>A; p.V418I; 15:99129615-99129615

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1483C>G; p.L495V; 15:99129846-99129846

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2333G>A; p.G778D; 15:99130696-99130696

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1847G>A; p.R616Q; 15:99130210-99130210

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2827G>A; p.E943K; 15:99131190-99131190

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2961G>A; p.K987K; 15:99131324-99131324

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2961G>A; p.K987K; 15:99131324-99131324

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.2463T>G; p.G821G; 15:99130826-99130826

 breastcarcinomaSubstitution - coding silent

c.1409C>T; p.S470L; 15:99129772-99129772

 skinmalignant_melanomaSubstitution - Missense

c.3451-7C>T; p.?; 15:99132743-99132743

 skinmalignant_melanomaUnknown

c.1020C>A; p.S340S; 15:99129383-99129383

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1710C>A; p.S570R; 15:99130073-99130073

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2094C>T; p.S698S; 15:99130457-99130457

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2476G>A; p.E826K; 15:99130839-99130839

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.3611G>A; p.R1204K; 15:99132910-99132910

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2268C>T; p.S756S; 15:99130631-99130631

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2470G>A; p.E824K; 15:99130833-99130833

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.3606C>A; p.A1202A; 15:99132905-99132905

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1259G>A; p.S420N; 15:99129622-99129622

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.969G>A; p.V323V; 15:99126758-99126758

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.3192T>C; p.F1064F; 15:99131555-99131555

 thyroidother; neoplasmSubstitution - coding silent

c.1512G>A; p.T504T; 15:99129875-99129875

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2682G>A; p.A894A; 15:99131045-99131045

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1248A>T; p.K416N; 15:99129611-99129611

 skinmalignant_melanomaSubstitution - Missense

c.3540G>A; p.A1180A; 15:99132839-99132839

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1248A>T; p.K416N; 15:99129611-99129611

 skinmalignant_melanomaSubstitution - Missense

c.2881G>A; p.E961K; 15:99131244-99131244

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1343C>A; p.P448Q; 15:99129706-99129706

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2421T>C; p.P807P; 15:99130784-99130784

 thyroidother; neoplasmSubstitution - coding silent

c.1752G>T; p.Q584H; 15:99130115-99130115

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2773G>T; p.E925*; 15:99131136-99131136

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2542G>A; p.V848M; 15:99130905-99130905

 skinmalignant_melanomaSubstitution - Missense

c.854C>T; p.A285V; 15:99113637-99113637

 livercarcinomaSubstitution - Missense

c.854C>T; p.A285V; 15:99113637-99113637

 livercarcinomaSubstitution - Missense

c.2328G>A; p.S776S; 15:99130691-99130691

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2253C>A; p.P751P; 15:99130616-99130616

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisSubstitution - coding silent

c.3227C>T; p.S1076L; 15:99131590-99131590

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1109G>A; p.S370N; 15:99129472-99129472

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1819G>A; p.G607S; 15:99130182-99130182

 ovaryother; neoplasmSubstitution - Missense

c.1819G>A; p.G607S; 15:99130182-99130182

 ovaryother; neoplasmSubstitution - Missense

c.1937T>G; p.L646R; 15:99130300-99130300

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2888T>C; p.M963T; 15:99131251-99131251

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2681C>T; p.A894V; 15:99131044-99131044

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2339delG; p.L782fs*36; 15:99130702-99130702

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.998C>G; p.P333R; 15:99126787-99126787

 breastcarcinomaSubstitution - Missense

c.2215A>G; p.R739G; 15:99130578-99130578

 oesophaguscarcinomaSubstitution - Missense

c.2283G>T; p.E761D; 15:99130646-99130646

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1738C>T; p.L580L; 15:99130101-99130101

 skinmalignant_melanomaSubstitution - coding silent

c.89G>A; p.R30Q; 15:99105288-99105288

 breastcarcinomaSubstitution - Missense

c.1053A>C; p.E351D; 15:99129416-99129416

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1593C>T; p.S531S; 15:99129956-99129956

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.2377G>A; p.D793N; 15:99130740-99130740

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.641G>T; p.R214L; 15:99105840-99105840

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1592C>T; p.S531F; 15:99129955-99129955

 skinmalignant_melanomaSubstitution - Missense

c.3613G>T; p.E1205*; 15:99132912-99132912

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1511C>T; p.T504M; 15:99129874-99129874

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1477G>A; p.V493I; 15:99129840-99129840

 central_nervous_system; braingliomaSubstitution - Missense

c.1487G>A; p.G496E; 15:99129850-99129850

 breastcarcinomaSubstitution - Missense

c.1714_1715insGA; p.V576fs*6; 15:99130077-99130078

 endometriumcarcinoma; endometrioid_carcinomaInsertion - Frameshift

c.1550C>T; p.T517I; 15:99129913-99129913

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.3733G>A; p.E1245K; 15:99133032-99133032

 skin; trunkmalignant_melanomaSubstitution - Missense

c.757G>C; p.A253P; 15:99105959-99105959

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.3160G>A; p.G1054R; 15:99131523-99131523

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1818C>T; p.T606T; 15:99130181-99130181

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1818C>T; p.T606T; 15:99130181-99130181

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.3383T>G; p.L1128R; 15:99131746-99131746

 livercarcinomaSubstitution - Missense

c.3383T>G; p.L1128R; 15:99131746-99131746

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.3080A>T; p.E1027V; 15:99131443-99131443

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2938A>G; p.S980G; 15:99131301-99131301

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2580C>G; p.I860M; 15:99130943-99130943

 breastcarcinomaSubstitution - Missense

c.3539C>T; p.A1180V; 15:99132838-99132838

 central_nervous_system; braingliomaSubstitution - Missense

c.1136G>T; p.G379V; 15:99129499-99129499

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.3132A>G; p.P1044P; 15:99131495-99131495

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1908C>T; p.T636T; 15:99130271-99130271

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1814G>A; p.G605E; 15:99130177-99130177

 breastcarcinomaSubstitution - Missense

c.3497C>T; p.A1166V; 15:99132796-99132796

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1277C>A; p.T426N; 15:99129640-99129640

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2008G>A; p.V670M; 15:99130371-99130371

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1140C>A; p.H380Q; 15:99129503-99129503

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2637C>T; p.D879D; 15:99131000-99131000

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.3590G>T; p.G1197V; 15:99132889-99132889

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1168G>A; p.G390R; 15:99129531-99129531

 skinmalignant_melanomaSubstitution - Missense

c.2752G>T; p.E918*; 15:99131115-99131115

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2711C>T; p.T904I; 15:99131074-99131074

 skin; trunkmalignant_melanomaSubstitution - Missense

c.1598A>T; p.E533V; 15:99129961-99129961

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.3678G>A; p.R1226R; 15:99132977-99132977

 breastcarcinomaSubstitution - coding silent

c.2768delA; p.E925fs*12; 15:99131131-99131131

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1572C>T; p.F524F; 15:99129935-99129935

 skinmalignant_melanomaSubstitution - coding silent

c.1650G>A; p.Q550Q; 15:99130013-99130013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1572C>T; p.F524F; 15:99129935-99129935

 skinmalignant_melanomaSubstitution - coding silent

c.932+1G>A; p.?; 15:99113716-99113716

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1173T>G; p.G391G; 15:99129536-99129536

 skinmalignant_melanomaSubstitution - coding silent

c.1776G>A; p.P592P; 15:99130139-99130139

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.949G>T; p.E317*; 15:99126738-99126738

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.465_466delGC; p.A159fs*114; 15:99105664-99105665

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.1797G>A; p.V599V; 15:99130160-99130160

 skinmalignant_melanomaSubstitution - coding silent

c.1715G>A; p.R572Q; 15:99130078-99130078

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.3591G>T; p.G1197G; 15:99132890-99132890

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1715G>A; p.R572Q; 15:99130078-99130078

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.897G>A; p.V299V; 15:99113680-99113680

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2847G>A; p.V949V; 15:99131210-99131210

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1125T>C; p.S375S; 15:99129488-99129488

 livercarcinomaSubstitution - coding silent

c.3110G>C; p.S1037T; 15:99131473-99131473

 eye; uveal_tractmalignant_melanoma; mixedSubstitution - Missense

c.2145G>A; p.G715G; 15:99130508-99130508

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.1362G>T; p.R454S; 15:99129725-99129725

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.702_702+1insG; p.A235fs*39; 15:99105903-99105903

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.2791G>A; p.E931K; 15:99131154-99131154

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2385A>G; p.T795T; 15:99130748-99130748

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.562G>A; p.A188T; 15:99105761-99105761

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.3524G>T; p.G1175V; 15:99132823-99132823

 central_nervous_system; braingliomaSubstitution - Missense

c.1199C>T; p.S400L; 15:99129562-99129562

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1060A>T; p.R354W; 15:99129423-99129423

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.3413G>A; p.R1138Q; 15:99131776-99131776

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1715_1716delGA; p.E575fs*4; 15:99130078-99130079

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.1715_1716delGA; p.E575fs*4; 15:99130078-99130079

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1715_1716delGA; p.E575fs*4; 15:99130078-99130079

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.3689C>T; p.S1230L; 15:99132988-99132988

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.745C>T; p.R249W; 15:99105947-99105947

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2524G>A; p.D842N; 15:99130887-99130887

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.3010G>A; p.V1004I; 15:99131373-99131373

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2284G>A; p.E762K; 15:99130647-99130647

 breastcarcinomaSubstitution - Missense

c.2433G>A; p.T811T; 15:99130796-99130796

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.3010G>A; p.V1004I; 15:99131373-99131373

 kidneyother; neoplasmSubstitution - Missense

c.61C>T; p.R21W; 15:99105260-99105260

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.910_912delAGT; p.S304delS; 15:99113693-99113695

 ovarycarcinoma; serous_carcinomaDeletion - In frame

c.3151G>T; p.E1051*; 15:99131514-99131514

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2868G>T; p.E956D; 15:99131231-99131231

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2124C>T; p.S708S; 15:99130487-99130487

 livercarcinomaSubstitution - coding silent

c.2124C>T; p.S708S; 15:99130487-99130487

 livercarcinomaSubstitution - coding silent

c.3275G>A; p.R1092H; 15:99131638-99131638

 livercarcinomaSubstitution - Missense

c.2416C>T; p.Q806*; 15:99130779-99130779

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2562C>T; p.I854I; 15:99130925-99130925

 skinmalignant_melanomaSubstitution - coding silent

c.2651_2653delAGA; p.K885delK; 15:99131014-99131016

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningDeletion - In frame

c.1711G>A; p.V571M; 15:99130074-99130074

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; polycythaemia_veraSubstitution - Missense

c.2791G>T; p.E931*; 15:99131154-99131154

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2791G>T; p.E931*; 15:99131154-99131154

 breastcarcinomaSubstitution - Nonsense

c.2030G>A; p.G677E; 15:99130393-99130393

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2030G>A; p.G677E; 15:99130393-99130393

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.3173C>T; p.P1058L; 15:99131536-99131536

 thyroidother; neoplasmSubstitution - Missense

c.1820_1821GT>AA; p.G607>?; 15:99130183-99130184

 NSmalignant_melanomaComplex

c.3726T>C; p.N1242N; 15:99133025-99133025

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.876C>T; p.D292D; 15:99113659-99113659

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1750C>A; p.Q584K; 15:99130113-99130113

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1404C>T; p.R468R; 15:99129767-99129767

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.633G>C; p.E211D; 15:99105832-99105832

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1931G>A; p.S644N; 15:99130294-99130294

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1817C>T; p.T606I; 15:99130180-99130180

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.3012C>G; p.V1004V; 15:99131375-99131375

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2028T>C; p.P676P; 15:99130391-99130391

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.3274C>T; p.R1092C; 15:99131637-99131637

 prostatecarcinomaSubstitution - Missense

c.1690G>A; p.D564N; 15:99130053-99130053

 skinmalignant_melanomaSubstitution - Missense

c.2986G>A; p.V996M; 15:99131349-99131349

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2191C>A; p.L731I; 15:99130554-99130554

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1969G>T; p.A657S; 15:99130332-99130332

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.3628C>A; p.Q1210K; 15:99132927-99132927

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1706A>T; p.K569M; 15:99130069-99130069

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.3628C>A; p.Q1210K; 15:99132927-99132927

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1103A>G; p.N368S; 15:99129466-99129466

 livercarcinomaSubstitution - Missense

c.1103A>G; p.N368S; 15:99129466-99129466

 livercarcinomaSubstitution - Missense

c.3349G>C; p.E1117Q; 15:99131712-99131712

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2752G>A; p.E918K; 15:99131115-99131115

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2752G>A; p.E918K; 15:99131115-99131115

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.2752G>A; p.E918K; 15:99131115-99131115

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1200G>A; p.S400S; 15:99129563-99129563

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1806T>C; p.A602A; 15:99130169-99130169

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.905G>A; p.G302D; 15:99113688-99113688

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1791G>A; p.T597T; 15:99130154-99130154

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1728G>A; p.V576V; 15:99130091-99130091

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.891G>A; p.L297L; 15:99113674-99113674

 livercarcinomaSubstitution - coding silent

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