Entrez Gene

Basic Information
Gene ID	27253
Name	PCDH17
Synonymous	protocadherin 17;PCDH17;protocadherin 17
Definition	protocadherin 68\|protocadherin-17\|protocadherin-68
Position	13q21.1
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.07.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.3214T>C; p.L1072L; 13:57725028-57725028	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.562G>A; p.D188N; 13:57633108-57633108	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.798C>T; p.N266N; 13:57633344-57633344	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3214T>C; p.L1072L; 13:57725028-57725028	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3214T>C; p.L1072L; 13:57725028-57725028	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3214T>C; p.L1072L; 13:57725028-57725028	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3214T>C; p.L1072L; 13:57725028-57725028	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2115G>T; p.S705S; 13:57634661-57634661	pancreas	carcinoma	Substitution - coding silent
c.954G>T; p.E318D; 13:57633500-57633500	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1445A>C; p.H482P; 13:57633991-57633991	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.3190C>A; p.L1064M; 13:57725004-57725004	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1445A>C; p.H482P; 13:57633991-57633991	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1461G>A; p.P487P; 13:57634007-57634007	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3154G>T; p.G1052C; 13:57724968-57724968	upper_aerodigestive_tract; sinonasal_and_nasal_cavity	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1889G>A; p.G630D; 13:57634435-57634435	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2474T>C; p.V825A; 13:57635020-57635020	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2155C>T; p.L719F; 13:57634701-57634701	skin	malignant_melanoma	Substitution - Missense
c.1861G>A; p.G621R; 13:57634407-57634407	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2565+1G>T; p.?; 13:57635112-57635112	liver	carcinoma	Unknown
c.520G>A; p.D174N; 13:57633066-57633066	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3137C>A; p.P1046H; 13:57724951-57724951	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.577C>T; p.P193S; 13:57633123-57633123	skin	malignant_melanoma	Substitution - Missense
c.1254C>T; p.Y418Y; 13:57633800-57633800	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2909G>T; p.R970L; 13:57724723-57724723	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2472T>G; p.T824T; 13:57635018-57635018	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1948C>T; p.P650S; 13:57634494-57634494	skin	malignant_melanoma	Substitution - Missense
c.770C>A; p.P257Q; 13:57633316-57633316	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.890A>T; p.D297V; 13:57633436-57633436	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.388C>T; p.P130S; 13:57632934-57632934	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2717A>C; p.K906T; 13:57666753-57666753	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1265A>T; p.Y422F; 13:57633811-57633811	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3063C>A; p.A1021A; 13:57724877-57724877	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3080C>A; p.P1027H; 13:57724894-57724894	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.564C>A; p.D188E; 13:57633110-57633110	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2459C>T; p.S820F; 13:57635005-57635005	skin	malignant_melanoma	Substitution - Missense
c.3133G>A; p.E1045K; 13:57724947-57724947	skin; extremity	malignant_melanoma	Substitution - Missense
c.927G>C; p.L309L; 13:57633473-57633473	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1936C>A; p.R646S; 13:57634482-57634482	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1357A>G; p.N453D; 13:57633903-57633903	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1957G>T; p.E653*; 13:57634503-57634503	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2589C>T; p.P863P; 13:57666491-57666491	skin	malignant_melanoma	Substitution - coding silent
c.1770C>T; p.N590N; 13:57634316-57634316	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.889G>T; p.D297Y; 13:57633435-57633435	central_nervous_system; brain	atypical_teratoid-rhabdoid_tumour	Substitution - Missense
c.70T>C; p.S24P; 13:57632616-57632616	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1770C>T; p.N590N; 13:57634316-57634316	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2007C>T; p.G669G; 13:57634553-57634553	liver	carcinoma	Substitution - coding silent
c.2007C>T; p.G669G; 13:57634553-57634553	liver	carcinoma	Substitution - coding silent
c.1585C>T; p.P529S; 13:57634131-57634131	skin	malignant_melanoma	Substitution - Missense
c.3010G>T; p.D1004Y; 13:57724824-57724824	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.630G>A; p.T210T; 13:57633176-57633176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.68A>G; p.Y23C; 13:57632614-57632614	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1346C>T; p.S449F; 13:57633892-57633892	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1035C>A; p.N345K; 13:57633581-57633581	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2932G>T; p.V978F; 13:57724746-57724746	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1593C>T; p.N531N; 13:57634139-57634139	pancreas	carcinoma	Substitution - coding silent
c.3479G>T; p.*1160L; 13:57725293-57725293	large_intestine; caecum	carcinoma; adenocarcinoma	Nonstop extension
c.765C>T; p.N255N; 13:57633311-57633311	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2874C>T; p.F958F; 13:57724688-57724688	skin	malignant_melanoma	Substitution - coding silent
c.361G>C; p.E121Q; 13:57632907-57632907	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.1853G>A; p.G618D; 13:57634399-57634399	ovary	other; neoplasm	Substitution - Missense
c.2066C>T; p.P689L; 13:57634612-57634612	pancreas	carcinoma	Substitution - Missense
c.2581G>A; p.A861T; 13:57666483-57666483	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2882C>G; p.A961G; 13:57724696-57724696	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2581G>A; p.A861T; 13:57666483-57666483	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2578C>T; p.P860S; 13:57666480-57666480	skin	malignant_melanoma	Substitution - Missense
c.2578C>T; p.P860S; 13:57666480-57666480	skin	malignant_melanoma	Substitution - Missense
c.1681G>A; p.A561T; 13:57634227-57634227	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3452G>A; p.G1151E; 13:57725266-57725266	skin	malignant_melanoma	Substitution - Missense
c.3452G>A; p.G1151E; 13:57725266-57725266	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2353G>A; p.V785M; 13:57634899-57634899	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2909G>A; p.R970H; 13:57724723-57724723	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.3395C>A; p.S1132Y; 13:57725209-57725209	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.210C>T; p.S70S; 13:57632756-57632756	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2124C>T; p.L708L; 13:57634670-57634670	skin	malignant_melanoma	Substitution - coding silent
c.3179A>C; p.K1060T; 13:57724993-57724993	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2974_2975CC>TT; p.P992F; 13:57724788-57724789	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1570T>C; p.Y524H; 13:57634116-57634116	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2653G>T; p.A885S; 13:57666689-57666689	liver	carcinoma	Substitution - Missense
c.1309G>A; p.E437K; 13:57633855-57633855	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2049G>A; p.S683S; 13:57634595-57634595	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2648A>C; p.E883A; 13:57666684-57666684	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1132G>T; p.D378Y; 13:57633678-57633678	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3059A>T; p.K1020I; 13:57724873-57724873	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.142C>G; p.L48V; 13:57632688-57632688	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2354T>G; p.V785G; 13:57634900-57634900	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2044C>A; p.R682S; 13:57634590-57634590	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1053C>A; p.I351I; 13:57633599-57633599	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2260delG; p.G755fs*26; 13:57634806-57634806	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1407G>A; p.P469P; 13:57633953-57633953	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2195G>A; p.R732H; 13:57634741-57634741	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.441G>A; p.P147P; 13:57632987-57632987	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2829A>C; p.E943D; 13:57724643-57724643	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.441G>A; p.P147P; 13:57632987-57632987	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.270C>T; p.I90I; 13:57632816-57632816	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1407G>A; p.P469P; 13:57633953-57633953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1563C>T; p.I521I; 13:57634109-57634109	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2114C>T; p.S705L; 13:57634660-57634660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1867C>T; p.L623F; 13:57634413-57634413	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2114C>T; p.S705L; 13:57634660-57634660	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1646A>G; p.E549G; 13:57634192-57634192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1901A>T; p.H634L; 13:57634447-57634447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2260G>A; p.G754R; 13:57634806-57634806	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2184C>G; p.V728V; 13:57634730-57634730	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2849C>T; p.S950F; 13:57724663-57724663	skin	malignant_melanoma	Substitution - Missense
c.522C>T; p.D174D; 13:57633068-57633068	ovary	other; neoplasm	Substitution - coding silent
c.1177G>C; p.G393R; 13:57633723-57633723	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1992G>T; p.K664N; 13:57634538-57634538	kidney	Wilms_tumour	Substitution - Missense
c.1506C>G; p.G502G; 13:57634052-57634052	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2162C>T; p.A721V; 13:57634708-57634708	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.522C>T; p.D174D; 13:57633068-57633068	ovary	other; neoplasm	Substitution - coding silent
c.2849C>T; p.S950F; 13:57724663-57724663	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1555G>A; p.V519M; 13:57634101-57634101	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.82_83GA>AG; p.E28>?; 13:57632628-57632629	lung	carcinoma; adenocarcinoma	Complex
c.448C>T; p.R150C; 13:57632994-57632994	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1689G>A; p.L563L; 13:57634235-57634235	skin	malignant_melanoma	Substitution - coding silent
c.3317G>A; p.R1106K; 13:57725131-57725131	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3280G>A; p.D1094N; 13:57725094-57725094	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1555G>A; p.V519M; 13:57634101-57634101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1555G>A; p.V519M; 13:57634101-57634101	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.790G>A; p.D264N; 13:57633336-57633336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.790G>A; p.D264N; 13:57633336-57633336	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3355G>T; p.E1119*; 13:57725169-57725169	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.28C>T; p.L10F; 13:57632574-57632574	skin	malignant_melanoma	Substitution - Missense
c.2707G>C; p.D903H; 13:57666743-57666743	skin	malignant_melanoma	Substitution - Missense
c.2290delA; p.N765fs*16; 13:57634836-57634836	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2886T>G; p.N962K; 13:57724700-57724700	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2527G>A; p.A843T; 13:57635073-57635073	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.440C>T; p.P147L; 13:57632986-57632986	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3347C>A; p.A1116D; 13:57725161-57725161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.564C>T; p.D188D; 13:57633110-57633110	ovary	other; neoplasm	Substitution - coding silent
c.1212C>T; p.G404G; 13:57633758-57633758	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.3218C>A; p.P1073H; 13:57725032-57725032	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.425C>T; p.S142L; 13:57632971-57632971	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.425C>T; p.S142L; 13:57632971-57632971	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1017C>G; p.V339V; 13:57633563-57633563	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1971C>A; p.P657P; 13:57634517-57634517	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1125G>T; p.R375R; 13:57633671-57633671	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.382A>G; p.N128D; 13:57632928-57632928	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.147G>A; p.P49P; 13:57632693-57632693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.600T>G; p.A200A; 13:57633146-57633146	thyroid	other; neoplasm	Substitution - coding silent
c.1414T>C; p.F472L; 13:57633960-57633960	skin	malignant_melanoma	Substitution - Missense
c.147G>A; p.P49P; 13:57632693-57632693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2810G>A; p.C937Y; 13:57724624-57724624	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2374G>A; p.A792T; 13:57634920-57634920	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.2146T>C; p.S716P; 13:57634692-57634692	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1796G>T; p.R599L; 13:57634342-57634342	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1485C>T; p.L495L; 13:57634031-57634031	skin	malignant_melanoma	Substitution - coding silent
c.829G>A; p.E277K; 13:57633375-57633375	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3433C>T; p.L1145F; 13:57725247-57725247	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3438G>T; p.L1146F; 13:57725252-57725252	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.750G>A; p.V250V; 13:57633296-57633296	skin	malignant_melanoma	Substitution - coding silent
c.465C>A; p.S155R; 13:57633011-57633011	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2817T>G; p.N939K; 13:57724631-57724631	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2029G>A; p.A677T; 13:57634575-57634575	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3033C>T; p.L1011L; 13:57724847-57724847	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.742T>C; p.Y248H; 13:57633288-57633288	skin	malignant_melanoma	Substitution - Missense
c.2764A>T; p.T922S; 13:57666800-57666800	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3302C>T; p.A1101V; 13:57725116-57725116	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2381C>A; p.S794Y; 13:57634927-57634927	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1699G>A; p.A567T; 13:57634245-57634245	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1831C>T; p.R611C; 13:57634377-57634377	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3188C>A; p.A1063D; 13:57725002-57725002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2907C>A; p.Y969*; 13:57724721-57724721	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1831C>T; p.R611C; 13:57634377-57634377	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2115G>A; p.S705S; 13:57634661-57634661	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2678G>T; p.G893V; 13:57666714-57666714	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3125C>A; p.A1042E; 13:57724939-57724939	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3214T>G; p.L1072V; 13:57725028-57725028	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3214T>G; p.L1072V; 13:57725028-57725028	prostate	carcinoma	Substitution - Missense
c.3327G>T; p.R1109R; 13:57725141-57725141	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3214T>G; p.L1072V; 13:57725028-57725028	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.3214T>G; p.L1072V; 13:57725028-57725028	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.578C>A; p.P193Q; 13:57633124-57633124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3214T>G; p.L1072V; 13:57725028-57725028	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2504G>C; p.S835T; 13:57635050-57635050	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.730G>T; p.E244*; 13:57633276-57633276	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2740G>A; p.V914I; 13:57666776-57666776	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.634G>A; p.V212M; 13:57633180-57633180	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.599C>T; p.A200V; 13:57633145-57633145	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1968G>A; p.T656T; 13:57634514-57634514	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1236C>A; p.F412L; 13:57633782-57633782	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.618G>A; p.Q206Q; 13:57633164-57633164	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1968G>A; p.T656T; 13:57634514-57634514	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3132C>T; p.I1044I; 13:57724946-57724946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2982G>T; p.G994G; 13:57724796-57724796	pancreas	carcinoma	Substitution - coding silent
c.2212C>T; p.R738C; 13:57634758-57634758	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1152C>T; p.N384N; 13:57633698-57633698	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2032A>C; p.K678Q; 13:57634578-57634578	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1152C>T; p.N384N; 13:57633698-57633698	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2182G>T; p.V728F; 13:57634728-57634728	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2217T>A; p.T739T; 13:57634763-57634763	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2032A>C; p.K678Q; 13:57634578-57634578	liver	carcinoma	Substitution - Missense
c.2477C>A; p.P826H; 13:57635023-57635023	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2405C>A; p.T802N; 13:57634951-57634951	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.284T>C; p.L95P; 13:57632830-57632830	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2252A>G; p.Q751R; 13:57634798-57634798	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.44C>T; p.A15V; 13:57632590-57632590	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1863G>T; p.G621G; 13:57634409-57634409	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3109A>T; p.S1037C; 13:57724923-57724923	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1033A>G; p.N345D; 13:57633579-57633579	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1529C>A; p.S510Y; 13:57634075-57634075	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2235C>T; p.A745A; 13:57634781-57634781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1937G>A; p.R646H; 13:57634483-57634483	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3374A>G; p.N1125S; 13:57725188-57725188	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2736G>C; p.M912I; 13:57666772-57666772	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1937G>A; p.R646H; 13:57634483-57634483	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3231A>T; p.Q1077H; 13:57725045-57725045	pancreas	carcinoma	Substitution - Missense
c.1190C>T; p.T397M; 13:57633736-57633736	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1278T>C; p.T426T; 13:57633824-57633824	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1278T>C; p.T426T; 13:57633824-57633824	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1539C>T; p.P513P; 13:57634085-57634085	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1940C>T; p.T647M; 13:57634486-57634486	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.633C>T; p.L211L; 13:57633179-57633179	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1124G>T; p.R375L; 13:57633670-57633670	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3389G>C; p.R1130T; 13:57725203-57725203	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.990T>C; p.P330P; 13:57633536-57633536	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.334G>A; p.D112N; 13:57632880-57632880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1349C>T; p.P450L; 13:57633895-57633895	pancreas	NS	Substitution - Missense
c.3128G>A; p.C1043Y; 13:57724942-57724942	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.334G>A; p.D112N; 13:57632880-57632880	oesophagus	carcinoma	Substitution - Missense
c.2510C>A; p.T837N; 13:57635056-57635056	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1301C>T; p.T434I; 13:57633847-57633847	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1060G>A; p.V354I; 13:57633606-57633606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1482G>C; p.V494V; 13:57634028-57634028	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2090G>A; p.G697D; 13:57634636-57634636	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.235G>A; p.A79T; 13:57632781-57632781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.178A>T; p.K60*; 13:57632724-57632724	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.210C>A; p.S70S; 13:57632756-57632756	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.591C>T; p.I197I; 13:57633137-57633137	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1394A>G; p.E465G; 13:57633940-57633940	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1064C>T; p.S355F; 13:57633610-57633610	skin	malignant_melanoma	Substitution - Missense
c.556C>T; p.R186C; 13:57633102-57633102	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2637T>A; p.F879L; 13:57666673-57666673	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2034G>C; p.K678N; 13:57634580-57634580	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1246G>A; p.E416K; 13:57633792-57633792	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1251C>A; p.N417K; 13:57633797-57633797	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1215G>A; p.G405G; 13:57633761-57633761	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.73G>A; p.V25M; 13:57632619-57632619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3361C>A; p.L1121I; 13:57725175-57725175	breast	carcinoma	Substitution - Missense
c.1348C>T; p.P450S; 13:57633894-57633894	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2647G>T; p.E883*; 13:57666683-57666683	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3213C>A; p.Y1071*; 13:57725027-57725027	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1530T>C; p.S510S; 13:57634076-57634076	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.2139C>A; p.S713R; 13:57634685-57634685	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1932G>T; p.E644D; 13:57634478-57634478	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2208G>C; p.E736D; 13:57634754-57634754	urinary_tract; bladder	carcinoma	Substitution - Missense
c.318C>T; p.L106L; 13:57632864-57632864	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1498G>A; p.D500N; 13:57634044-57634044	skin	malignant_melanoma	Substitution - Missense
c.318C>T; p.L106L; 13:57632864-57632864	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2700T>G; p.S900R; 13:57666736-57666736	skin	malignant_melanoma	Substitution - Missense
c.2678G>A; p.G893E; 13:57666714-57666714	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.658G>T; p.E220*; 13:57633204-57633204	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3399G>A; p.V1133V; 13:57725213-57725213	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2182G>A; p.V728I; 13:57634728-57634728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2259T>A; p.G753G; 13:57634805-57634805	breast	carcinoma	Substitution - coding silent
c.2189G>A; p.C730Y; 13:57634735-57634735	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1965G>A; p.V655V; 13:57634511-57634511	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.363G>T; p.E121D; 13:57632909-57632909	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1881C>T; p.I627I; 13:57634427-57634427	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.555C>T; p.S185S; 13:57633101-57633101	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1881C>T; p.I627I; 13:57634427-57634427	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2179G>A; p.A727T; 13:57634725-57634725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2179G>A; p.A727T; 13:57634725-57634725	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2179G>A; p.A727T; 13:57634725-57634725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1734C>A; p.D578E; 13:57634280-57634280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.472G>T; p.D158Y; 13:57633018-57633018	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2625-10T>C; p.?; 13:57666651-57666651	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.677C>A; p.T226N; 13:57633223-57633223	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.529G>A; p.G177S; 13:57633075-57633075	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1443G>A; p.V481V; 13:57633989-57633989	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.723G>A; p.P241P; 13:57633269-57633269	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2199G>A; p.E733E; 13:57634745-57634745	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2394C>T; p.F798F; 13:57634940-57634940	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.811G>A; p.D271N; 13:57633357-57633357	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3325C>T; p.R1109W; 13:57725139-57725139	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2394C>T; p.F798F; 13:57634940-57634940	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.811G>A; p.D271N; 13:57633357-57633357	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.328G>A; p.A110T; 13:57632874-57632874	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.776G>T; p.G259V; 13:57633322-57633322	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.412G>A; p.E138K; 13:57632958-57632958	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.412G>A; p.E138K; 13:57632958-57632958	breast	carcinoma	Substitution - Missense
c.2071G>T; p.G691W; 13:57634617-57634617	prostate	carcinoma	Substitution - Missense
c.808G>A; p.A270T; 13:57633354-57633354	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.808G>A; p.A270T; 13:57633354-57633354	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2801C>A; p.P934Q; 13:57724615-57724615	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Substitution - Missense
c.808G>A; p.A270T; 13:57633354-57633354	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3135G>T; p.E1045D; 13:57724949-57724949	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.358G>T; p.V120L; 13:57632904-57632904	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2683A>C; p.S895R; 13:57666719-57666719	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2609A>C; p.Q870P; 13:57666511-57666511	breast	carcinoma	Substitution - Missense
c.289C>T; p.R97C; 13:57632835-57632835	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1865G>A; p.R622H; 13:57634411-57634411	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.289C>T; p.R97C; 13:57632835-57632835	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1616C>T; p.S539F; 13:57634162-57634162	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3005G>A; p.G1002E; 13:57724819-57724819	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3005G>A; p.G1002E; 13:57724819-57724819	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.2844T>C; p.G948G; 13:57724658-57724658	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1324A>G; p.I442V; 13:57633870-57633870	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2014A>G; p.T672A; 13:57634560-57634560	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.258C>A; p.T86T; 13:57632804-57632804	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.724G>C; p.V242L; 13:57633270-57633270	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1796G>A; p.R599H; 13:57634342-57634342	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1796G>A; p.R599H; 13:57634342-57634342	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2261G>A; p.G754E; 13:57634807-57634807	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1796G>A; p.R599H; 13:57634342-57634342	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.120G>A; p.R40R; 13:57632666-57632666	skin	malignant_melanoma	Substitution - coding silent
c.1352C>T; p.P451L; 13:57633898-57633898	pancreas	carcinoma	Substitution - Missense
c.919G>T; p.G307C; 13:57633465-57633465	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1801G>A; p.A601T; 13:57634347-57634347	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1796G>A; p.R599H; 13:57634342-57634342	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1773C>A; p.D591E; 13:57634319-57634319	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.442G>T; p.G148C; 13:57632988-57632988	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3459C>T; p.D1153D; 13:57725273-57725273	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1605C>T; p.Y535Y; 13:57634151-57634151	pancreas	carcinoma	Substitution - coding silent
c.1605C>T; p.Y535Y; 13:57634151-57634151	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1605C>T; p.Y535Y; 13:57634151-57634151	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3360G>A; p.Q1120Q; 13:57725174-57725174	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3250C>A; p.Q1084K; 13:57725064-57725064	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1069C>T; p.R357C; 13:57633615-57633615	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1087G>A; p.E363K; 13:57633633-57633633	skin	malignant_melanoma	Substitution - Missense
c.2980G>A; p.G994R; 13:57724794-57724794	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2316C>T; p.S772S; 13:57634862-57634862	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3241C>G; p.P1081A; 13:57725055-57725055	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.333C>T; p.N111N; 13:57632879-57632879	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069C>T; p.R357C; 13:57633615-57633615	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.333C>T; p.N111N; 13:57632879-57632879	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2316C>T; p.S772S; 13:57634862-57634862	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1245G>A; p.E415E; 13:57633791-57633791	liver	carcinoma	Substitution - coding silent
c.2140A>C; p.T714P; 13:57634686-57634686	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1679C>T; p.P560L; 13:57634225-57634225	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1245G>A; p.E415E; 13:57633791-57633791	liver	carcinoma	Substitution - coding silent
c.1726G>A; p.V576M; 13:57634272-57634272	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1962C>T; p.D654D; 13:57634508-57634508	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2381C>T; p.S794F; 13:57634927-57634927	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2815A>G; p.N939D; 13:57724629-57724629	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.868G>A; p.V290M; 13:57633414-57633414	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1686C>T; p.H562H; 13:57634232-57634232	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2891C>T; p.A964V; 13:57724705-57724705	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1760C>T; p.T587M; 13:57634306-57634306	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.868G>A; p.V290M; 13:57633414-57633414	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1962C>T; p.D654D; 13:57634508-57634508	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1393G>A; p.E465K; 13:57633939-57633939	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3419G>A; p.R1140K; 13:57725233-57725233	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1723G>A; p.D575N; 13:57634269-57634269	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2164G>A; p.A722T; 13:57634710-57634710	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3451G>A; p.G1151R; 13:57725265-57725265	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1205G>T; p.G402V; 13:57633751-57633751	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.150T>C; p.P50P; 13:57632696-57632696	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2641G>A; p.D881N; 13:57666677-57666677	skin	malignant_melanoma	Substitution - Missense
c.665C>G; p.P222R; 13:57633211-57633211	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1393G>A; p.E465K; 13:57633939-57633939	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2352C>T; p.N784N; 13:57634898-57634898	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.930C>T; p.D310D; 13:57633476-57633476	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2340G>C; p.M780I; 13:57634886-57634886	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.3259G>A; p.D1087N; 13:57725073-57725073	skin	malignant_melanoma	Substitution - Missense
c.1893C>T; p.N631N; 13:57634439-57634439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2608C>T; p.Q870*; 13:57666510-57666510	liver	carcinoma	Substitution - Nonsense
c.1231C>G; p.P411A; 13:57633777-57633777	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2650A>C; p.R884R; 13:57666686-57666686	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3333C>T; p.S1111S; 13:57725147-57725147	skin	malignant_melanoma	Substitution - coding silent
c.734C>T; p.A245V; 13:57633280-57633280	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.734C>T; p.A245V; 13:57633280-57633280	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1722A>G; p.L574L; 13:57634268-57634268	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1368G>T; p.K456N; 13:57633914-57633914	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1509G>T; p.Q503H; 13:57634055-57634055	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2256delG; p.G753fs*28; 13:57634802-57634802	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3172G>A; p.E1058K; 13:57724986-57724986	skin	malignant_melanoma	Substitution - Missense
c.107G>T; p.G36V; 13:57632653-57632653	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.481G>A; p.A161T; 13:57633027-57633027	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3349G>T; p.V1117F; 13:57725163-57725163	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2197G>T; p.E733*; 13:57634743-57634743	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.2750C>A; p.A917E; 13:57666786-57666786	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1012A>G; p.T338A; 13:57633558-57633558	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.851G>T; p.S284I; 13:57633397-57633397	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.805G>A; p.D269N; 13:57633351-57633351	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.805G>A; p.D269N; 13:57633351-57633351	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1810G>T; p.G604C; 13:57634356-57634356	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.386C>T; p.A129V; 13:57632932-57632932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3109A>C; p.S1037R; 13:57724923-57724923	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3109A>C; p.S1037R; 13:57724923-57724923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2413C>A; p.P805T; 13:57634959-57634959	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2071G>A; p.G691R; 13:57634617-57634617	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.997G>T; p.A333S; 13:57633543-57633543	urinary_tract; bladder	carcinoma	Substitution - Missense
c.711C>T; p.N237N; 13:57633257-57633257	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1153G>A; p.G385R; 13:57633699-57633699	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.711C>T; p.N237N; 13:57633257-57633257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1799A>T; p.N600I; 13:57634345-57634345	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.3469G>T; p.V1157L; 13:57725283-57725283	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1920G>A; p.P640P; 13:57634466-57634466	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1920G>A; p.P640P; 13:57634466-57634466	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3409G>A; p.E1137K; 13:57725223-57725223	skin	malignant_melanoma	Substitution - Missense
c.1920G>A; p.P640P; 13:57634466-57634466	liver	carcinoma	Substitution - coding silent
c.1920G>A; p.P640P; 13:57634466-57634466	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.629C>T; p.T210M; 13:57633175-57633175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1512C>A; p.N504K; 13:57634058-57634058	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1512C>A; p.N504K; 13:57634058-57634058	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2548C>T; p.R850W; 13:57635094-57635094	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.625C>T; p.H209Y; 13:57633171-57633171	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1334G>A; p.R445Q; 13:57633880-57633880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.158G>A; p.R53H; 13:57632704-57632704	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3343G>T; p.G1115C; 13:57725157-57725157	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.712G>A; p.D238N; 13:57633258-57633258	oesophagus	carcinoma	Substitution - Missense
c.2917C>T; p.L973F; 13:57724731-57724731	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2679G>A; p.G893G; 13:57666715-57666715	skin	malignant_melanoma	Substitution - coding silent
c.3214T>A; p.L1072M; 13:57725028-57725028	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2791G>A; p.E931K; 13:57666827-57666827	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.3214T>A; p.L1072M; 13:57725028-57725028	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.712G>A; p.D238N; 13:57633258-57633258	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2100C>T; p.H700H; 13:57634646-57634646	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1978G>T; p.E660*; 13:57634524-57634524	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1640C>A; p.A547D; 13:57634186-57634186	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>A; p.V356M; 13:57633612-57633612	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1995G>C; p.V665V; 13:57634541-57634541	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.3475A>C; p.K1159Q; 13:57725289-57725289	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2407C>T; p.R803C; 13:57634953-57634953	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3457G>T; p.D1153Y; 13:57725271-57725271	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2419_2420AG>TA; p.S807>?; 13:57634965-57634966	large_intestine; colon	carcinoma; adenocarcinoma	Complex
c.1779G>A; p.A593A; 13:57634325-57634325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1124G>A; p.R375Q; 13:57633670-57633670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1277C>A; p.T426N; 13:57633823-57633823	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.3412G>A; p.V1138I; 13:57725226-57725226	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1193G>A; p.G398D; 13:57633739-57633739	skin	malignant_melanoma	Substitution - Missense
c.1159C>T; p.L387L; 13:57633705-57633705	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.146C>T; p.P49L; 13:57632692-57632692	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2262G>T; p.G754G; 13:57634808-57634808	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1123C>T; p.R375W; 13:57633669-57633669	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2469G>A; p.L823L; 13:57635015-57635015	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.507C>A; p.Y169*; 13:57633053-57633053	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1795C>T; p.R599C; 13:57634341-57634341	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2006G>A; p.G669D; 13:57634552-57634552	prostate	carcinoma	Substitution - Missense
c.2228G>A; p.R743H; 13:57634774-57634774	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1682C>A; p.A561E; 13:57634228-57634228	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1213G>A; p.G405R; 13:57633759-57633759	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.960C>T; p.D320D; 13:57633506-57633506	liver	carcinoma	Substitution - coding silent
c.81G>T; p.E27D; 13:57632627-57632627	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2365C>A; p.P789T; 13:57634911-57634911	liver	carcinoma	Substitution - Missense
c.3326G>T; p.R1109L; 13:57725140-57725140	skin	malignant_melanoma	Substitution - Missense
c.2179G>T; p.A727S; 13:57634725-57634725	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1548C>T; p.I516I; 13:57634094-57634094	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2518G>T; p.G840W; 13:57635064-57635064	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1788G>T; p.Q596H; 13:57634334-57634334	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>A; p.E204K; 13:57633156-57633156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.820C>G; p.P274A; 13:57633366-57633366	skin	malignant_melanoma	Substitution - Missense
c.515C>T; p.T172M; 13:57633061-57633061	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.610G>A; p.E204K; 13:57633156-57633156	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.515C>T; p.T172M; 13:57633061-57633061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3221C>A; p.T1074N; 13:57725035-57725035	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3014A>G; p.K1005R; 13:57724828-57724828	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.515C>T; p.T172M; 13:57633061-57633061	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.933T>C; p.Y311Y; 13:57633479-57633479	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.610G>A; p.E204K; 13:57633156-57633156	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.790G>T; p.D264Y; 13:57633336-57633336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3118A>C; p.T1040P; 13:57724932-57724932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3378G>T; p.R1126S; 13:57725192-57725192	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1777G>A; p.A593T; 13:57634323-57634323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1777G>A; p.A593T; 13:57634323-57634323	liver	carcinoma	Substitution - Missense
c.799G>A; p.A267T; 13:57633345-57633345	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.866G>A; p.R289H; 13:57633412-57633412	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1777G>A; p.A593T; 13:57634323-57634323	liver	carcinoma	Substitution - Missense
c.2236G>A; p.E746K; 13:57634782-57634782	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2349G>A; p.M783I; 13:57634895-57634895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2349G>A; p.M783I; 13:57634895-57634895	skin	malignant_melanoma	Substitution - Missense
c.910C>T; p.R304C; 13:57633456-57633456	skin	malignant_melanoma	Substitution - Missense
c.2961C>T; p.Y987Y; 13:57724775-57724775	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1796G>C; p.R599P; 13:57634342-57634342	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.192C>T; p.Y64Y; 13:57632738-57632738	breast	carcinoma	Substitution - coding silent
c.910C>T; p.R304C; 13:57633456-57633456	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2022C>T; p.S674S; 13:57634568-57634568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2121G>T; p.P707P; 13:57634667-57634667	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.225G>A; p.L75L; 13:57632771-57632771	ovary	other; neoplasm	Substitution - coding silent
c.216G>A; p.P72P; 13:57632762-57632762	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.50C>T; p.T17I; 13:57632596-57632596	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.888C>T; p.I296I; 13:57633434-57633434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1296C>T; p.R432R; 13:57633842-57633842	liver	carcinoma	Substitution - coding silent
c.585G>A; p.L195L; 13:57633131-57633131	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1296C>T; p.R432R; 13:57633842-57633842	liver	carcinoma	Substitution - coding silent
c.2982G>A; p.G994G; 13:57724796-57724796	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1533C>T; p.I511I; 13:57634079-57634079	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2844T>G; p.G948G; 13:57724658-57724658	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.345C>T; p.I115I; 13:57632891-57632891	skin	malignant_melanoma	Substitution - coding silent
c.3097C>T; p.P1033S; 13:57724911-57724911	skin	malignant_melanoma	Substitution - Missense
c.897G>C; p.K299N; 13:57633443-57633443	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2383C>T; p.P795S; 13:57634929-57634929	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1332G>A; p.A444A; 13:57633878-57633878	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3450G>T; p.R1150R; 13:57725264-57725264	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3061G>A; p.A1021T; 13:57724875-57724875	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2340G>T; p.M780I; 13:57634886-57634886	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.831A>G; p.E277E; 13:57633377-57633377	skin	malignant_melanoma	Substitution - coding silent
c.2925A>C; p.V975V; 13:57724739-57724739	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2962G>A; p.E988K; 13:57724776-57724776	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2439G>T; p.V813V; 13:57634985-57634985	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2962G>A; p.E988K; 13:57724776-57724776	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1914C>A; p.I638I; 13:57634460-57634460	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2962G>A; p.E988K; 13:57724776-57724776	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1855G>A; p.E619K; 13:57634401-57634401	skin	malignant_melanoma	Substitution - Missense
c.1647G>A; p.E549E; 13:57634193-57634193	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3294G>T; p.R1098S; 13:57725108-57725108	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.963G>C; p.V321V; 13:57633509-57633509	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3208C>T; p.Q1070*; 13:57725022-57725022	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.426G>T; p.S142S; 13:57632972-57632972	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3208C>T; p.Q1070*; 13:57725022-57725022	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1683G>A; p.A561A; 13:57634229-57634229	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1882G>A; p.V628M; 13:57634428-57634428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1683G>A; p.A561A; 13:57634229-57634229	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2932G>A; p.V978I; 13:57724746-57724746	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3323G>A; p.S1108N; 13:57725137-57725137	skin	malignant_melanoma	Substitution - Missense
c.3016C>T; p.R1006*; 13:57724830-57724830	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.453C>T; p.F151F; 13:57632999-57632999	skin	malignant_melanoma	Substitution - coding silent
c.2107G>A; p.D703N; 13:57634653-57634653	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1993G>A; p.V665M; 13:57634539-57634539	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.361G>T; p.E121*; 13:57632907-57632907	pancreas	NS	Substitution - Nonsense
c.1834G>A; p.A612T; 13:57634380-57634380	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1338C>T; p.D446D; 13:57633884-57633884	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.165C>T; p.G55G; 13:57632711-57632711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1607C>A; p.A536D; 13:57634153-57634153	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.361G>T; p.E121*; 13:57632907-57632907	pancreas	carcinoma	Substitution - Nonsense
c.2622A>G; p.Q874Q; 13:57666524-57666524	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.987C>A; p.N329K; 13:57633533-57633533	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.987C>A; p.N329K; 13:57633533-57633533	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.243C>T; p.S81S; 13:57632789-57632789	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3433C>A; p.L1145I; 13:57725247-57725247	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.165C>T; p.G55G; 13:57632711-57632711	oesophagus	carcinoma	Substitution - coding silent
c.1035C>T; p.N345N; 13:57633581-57633581	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1738G>A; p.A580T; 13:57634284-57634284	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2054G>T; p.S685I; 13:57634600-57634600	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1036G>A; p.D346N; 13:57633582-57633582	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.729C>T; p.F243F; 13:57633275-57633275	skin	malignant_melanoma	Substitution - coding silent
c.1676C>T; p.A559V; 13:57634222-57634222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1399G>A; p.D467N; 13:57633945-57633945	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1887C>T; p.D629D; 13:57634433-57634433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.807C>T; p.D269D; 13:57633353-57633353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2988G>T; p.K996N; 13:57724802-57724802	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1704G>A; p.T568T; 13:57634250-57634250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1470C>A; p.Y490*; 13:57634016-57634016	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.248T>C; p.L83P; 13:57632794-57632794	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3328G>A; p.D1110N; 13:57725142-57725142	skin	malignant_melanoma	Substitution - Missense
c.1641T>C; p.A547A; 13:57634187-57634187	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1059C>T; p.F353F; 13:57633605-57633605	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1412G>A; p.R471Q; 13:57633958-57633958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1059C>T; p.F353F; 13:57633605-57633605	pancreas	carcinoma	Substitution - coding silent
c.3458A>G; p.D1153G; 13:57725272-57725272	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2891C>A; p.A964D; 13:57724705-57724705	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.311T>A; p.L104Q; 13:57632857-57632857	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1335G>A; p.R445R; 13:57633881-57633881	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.847A>T; p.S283C; 13:57633393-57633393	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1677G>A; p.A559A; 13:57634223-57634223	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1431C>A; p.Y477*; 13:57633977-57633977	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1749C>T; p.I583I; 13:57634295-57634295	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2951C>T; p.T984I; 13:57724765-57724765	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1195G>A; p.G399S; 13:57633741-57633741	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.98C>T; p.T33M; 13:57632644-57632644	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1915G>A; p.D639N; 13:57634461-57634461	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3017G>A; p.R1006Q; 13:57724831-57724831	skin	malignant_melanoma	Substitution - Missense
c.565G>T; p.G189C; 13:57633111-57633111	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1436T>C; p.L479P; 13:57633982-57633982	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3017G>A; p.R1006Q; 13:57724831-57724831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1500C>A; p.D500E; 13:57634046-57634046	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2974C>T; p.P992S; 13:57724788-57724788	skin	malignant_melanoma	Substitution - Missense
c.1076G>A; p.G359E; 13:57633622-57633622	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2062C>T; p.L688F; 13:57634608-57634608	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136G>C; p.R379P; 13:57633682-57633682	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2697C>A; p.D899E; 13:57666733-57666733	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2004C>T; p.H668H; 13:57634550-57634550	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2745G>A; p.R915R; 13:57666781-57666781	skin	malignant_melanoma	Substitution - coding silent
c.1590G>A; p.T530T; 13:57634136-57634136	skin	malignant_melanoma	Substitution - coding silent
c.1750G>A; p.V584M; 13:57634296-57634296	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.911G>A; p.R304H; 13:57633457-57633457	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.517C>T; p.R173C; 13:57633063-57633063	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1914C>T; p.I638I; 13:57634460-57634460	skin	malignant_melanoma	Substitution - coding silent
c.3326G>A; p.R1109Q; 13:57725140-57725140	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.607C>A; p.R203S; 13:57633153-57633153	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.652G>A; p.G218S; 13:57633198-57633198	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2065C>A; p.P689T; 13:57634611-57634611	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3100T>A; p.S1034T; 13:57724914-57724914	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1704G>T; p.T568T; 13:57634250-57634250	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3107C>A; p.S1036*; 13:57724921-57724921	liver	carcinoma	Substitution - Nonsense
c.3107C>A; p.S1036*; 13:57724921-57724921	liver	carcinoma	Substitution - Nonsense
c.33A>T; p.L11L; 13:57632579-57632579	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3194C>G; p.A1065G; 13:57725008-57725008	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.215C>T; p.P72L; 13:57632761-57632761	skin	malignant_melanoma	Substitution - Missense
c.3479_3480insA; p.1160; 13:57725293-57725294	breast	carcinoma	Substitution - coding silent
c.2481G>A; p.Q827Q; 13:57635027-57635027	skin	malignant_melanoma	Substitution - coding silent
c.625C>A; p.H209N; 13:57633171-57633171	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2490G>C; p.A830A; 13:57635036-57635036	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.66C>T; p.N22N; 13:57632612-57632612	pancreas	carcinoma	Substitution - coding silent
c.265C>A; p.R89S; 13:57632811-57632811	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.977T>A; p.L326Q; 13:57633523-57633523	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.F109F; 13:57632873-57632873	skin	malignant_melanoma	Substitution - coding silent
c.2890G>T; p.A964S; 13:57724704-57724704	liver	carcinoma	Substitution - Missense
c.1929C>T; p.G643G; 13:57634475-57634475	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.951G>A; p.L317L; 13:57633497-57633497	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3266C>A; p.P1089H; 13:57725080-57725080	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.2989A>C; p.T997P; 13:57724803-57724803	breast	carcinoma	Substitution - Missense
c.3141C>T; p.C1047C; 13:57724955-57724955	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1549G>A; p.G517S; 13:57634095-57634095	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2890G>T; p.A964S; 13:57724704-57724704	liver	carcinoma	Substitution - Missense
c.2186A>T; p.K729M; 13:57634732-57634732	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.15C>T; p.I5I; 13:57632561-57632561	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1845C>T; p.S615S; 13:57634391-57634391	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1333C>T; p.R445W; 13:57633879-57633879	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1513G>A; p.G505S; 13:57634059-57634059	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2949G>C; p.E983D; 13:57724763-57724763	adrenal_gland; adrenal_gland	adrenal_cortical_adenoma; cortisol_producing	Substitution - Missense
c.3457G>A; p.D1153N; 13:57725271-57725271	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3457G>A; p.D1153N; 13:57725271-57725271	skin	malignant_melanoma	Substitution - Missense
c.2068G>A; p.E690K; 13:57634614-57634614	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3319G>A; p.A1107T; 13:57725133-57725133	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1617C>T; p.S539S; 13:57634163-57634163	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.498C>G; p.L166L; 13:57633044-57633044	breast	carcinoma; lobular_carcinoma	Substitution - coding silent
c.2068G>A; p.E690K; 13:57634614-57634614	breast	carcinoma	Substitution - Missense
c.856G>A; p.V286M; 13:57633402-57633402	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1096C>T; p.P366S; 13:57633642-57633642	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1627G>T; p.E543*; 13:57634173-57634173	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2382C>T; p.S794S; 13:57634928-57634928	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1627G>T; p.E543*; 13:57634173-57634173	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.900C>T; p.T300T; 13:57633446-57633446	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1627G>T; p.E543*; 13:57634173-57634173	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.570C>A; p.T190T; 13:57633116-57633116	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.917A>T; p.K306M; 13:57633463-57633463	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3050C>T; p.P1017L; 13:57724864-57724864	skin	malignant_melanoma	Substitution - Missense
c.93C>T; p.A31A; 13:57632639-57632639	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1671G>A; p.S557S; 13:57634217-57634217	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.937G>A; p.E313K; 13:57633483-57633483	skin	malignant_melanoma	Substitution - Missense
c.3158C>T; p.S1053F; 13:57724972-57724972	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3042C>T; p.N1014N; 13:57724856-57724856	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1670_1671insG; p.A559fs*20; 13:57634216-57634217	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2272_2274delAAG; p.K761delK; 13:57634818-57634820	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.782T>A; p.V261E; 13:57633328-57633328	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1481T>C; p.V494A; 13:57634027-57634027	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1541C>T; p.S514L; 13:57634087-57634087	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1269G>A; p.T423T; 13:57633815-57633815	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.842C>G; p.S281C; 13:57633388-57633388	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1537C>T; p.P513S; 13:57634083-57634083	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2565G>T; p.Q855H; 13:57635111-57635111	liver	carcinoma	Substitution - Missense
c.1541C>T; p.S514L; 13:57634087-57634087	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1795C>A; p.R599S; 13:57634341-57634341	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1541C>T; p.S514L; 13:57634087-57634087	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1737C>T; p.N579N; 13:57634283-57634283	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.686T>C; p.I229T; 13:57633232-57633232	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.735G>A; p.A245A; 13:57633281-57633281	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3180A>C; p.K1060N; 13:57724994-57724994	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.40C>A; p.P14T; 13:57632586-57632586	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1737C>T; p.N579N; 13:57634283-57634283	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2141C>T; p.T714I; 13:57634687-57634687	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1737C>T; p.N579N; 13:57634283-57634283	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3327G>A; p.R1109R; 13:57725141-57725141	skin	malignant_melanoma	Substitution - coding silent

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]