Entrez Gene

Basic Information
Gene ID	27316
Name	RBMX
Synonymous	RNA binding motif protein, X-linked;RBMX;RNA binding motif protein, X-linked
Definition	RNA binding motif protein, X chromosome\|RNA-binding motif protein, X chromosome\|glycoprotein p43\|heterogeneous nuclear ribonucleoprotein G\|hnRNP G
Position	Xq26.3
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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The ratio of the loss-of-function mutations over missense mutations is 0.28.

The copy number variations for various cancers

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There is no record for RBMX

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.124G>T; p.D42Y; 23:136879109-136879109	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1055C>T; p.S352F; 23:136874263-136874263	skin	malignant_melanoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; tonsil	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	thyroid	other; neoplasm	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.902C>T; p.P301L; 23:136874416-136874416	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1135G>C; p.G379R; 23:136874183-136874183	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1107C>T; p.R369R; 23:136874211-136874211	thyroid	other; neoplasm	Substitution - coding silent
c.1107C>T; p.R369R; 23:136874211-136874211	thyroid	other; neoplasm	Substitution - coding silent
c.1107C>T; p.R369R; 23:136874211-136874211	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1107C>T; p.R369R; 23:136874211-136874211	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.15T>A; p.D5E; 23:136879413-136879413	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.992G>A; p.R331Q; 23:136874326-136874326	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.992G>A; p.R331Q; 23:136874326-136874326	prostate	carcinoma	Substitution - Missense
c.1_2insAT; p.?; 23:136879426-136879427	eye; uveal_tract	malignant_melanoma	Unknown
c.899C>A; p.P300H; 23:136874419-136874419	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.803G>A; p.R268H; 23:136875148-136875148	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.561A>G; p.R187R; 23:136875566-136875566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.561A>G; p.R187R; 23:136875566-136875566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.561A>G; p.R187R; 23:136875566-136875566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.507A>G; p.G169G; 23:136876537-136876537	liver	carcinoma	Substitution - coding silent
c.507A>G; p.G169G; 23:136876537-136876537	liver	carcinoma	Substitution - coding silent
c.507A>G; p.G169G; 23:136876537-136876537	thyroid	other; neoplasm	Substitution - coding silent
c.507A>G; p.G169G; 23:136876537-136876537	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.507A>G; p.G169G; 23:136876537-136876537	liver	carcinoma	Substitution - coding silent
c.1086T>C; p.D362D; 23:136874232-136874232	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1A>T; p.M1L; 23:136879427-136879427	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.818C>T; p.S273L; 23:136875133-136875133	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1105C>T; p.R369C; 23:136874213-136874213	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.290C>T; p.P97L; 23:136878013-136878013	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.890C>T; p.T297I; 23:136874428-136874428	liver	carcinoma	Substitution - Missense
c.37G>T; p.G13C; 23:136879391-136879391	urinary_tract; bladder	carcinoma	Substitution - Missense
c.890C>T; p.T297I; 23:136874428-136874428	liver	carcinoma	Substitution - Missense
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.905_906insCC; p.S303fs*>90; 23:136874412-136874413	NS	NS	Insertion - Frameshift
c.183C>T; p.D61D; 23:136879050-136879050	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.758A>T; p.D253V; 23:136875282-136875282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.624C>T; p.S208S; 23:136875503-136875503	skin	malignant_melanoma	Substitution - coding silent
c.217-3delT; p.?; 23:136878089-136878089	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.617A>C; p.Y206S; 23:136875510-136875510	skin; neck	malignant_melanoma	Substitution - Missense
c.442C>A; p.P148T; 23:136876602-136876602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	peritoneum; appendix	other; pseudomyxoma_peritonei	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	liver	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	breast	carcinoma	Insertion - Frameshift
c.784G>T; p.D262Y; 23:136875167-136875167	urinary_tract; bladder	carcinoma	Substitution - Missense
c.315_316insTT; p.P106fs*32; 23:136877987-136877988	NS	NS	Insertion - Frameshift
c.311G>A; p.G104D; 23:136877992-136877992	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.586A>G; p.R196G; 23:136875541-136875541	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.66A>C; p.K22N; 23:136879362-136879362	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.376G>A; p.G126R; 23:136877927-136877927	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.97C>T; p.R33*; 23:136879331-136879331	kidney	other; neoplasm	Substitution - Nonsense
c.891A>G; p.T297T; 23:136874427-136874427	thyroid	other; neoplasm	Substitution - coding silent
c.97C>T; p.R33*; 23:136879331-136879331	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1081C>T; p.R361C; 23:136874237-136874237	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.663A>G; p.S221S; 23:136875377-136875377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.462A>T; p.P154P; 23:136876582-136876582	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.949C>T; p.R317C; 23:136874369-136874369	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.288G>A; p.P96P; 23:136878015-136878015	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.924T>A; p.S308R; 23:136874394-136874394	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	liver	carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1015C>G; p.R339G; 23:136874303-136874303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.500C>T; p.P167L; 23:136876544-136876544	kidney	other; neoplasm	Substitution - Missense
c.889A>G; p.T297A; 23:136874429-136874429	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.889A>G; p.T297A; 23:136874429-136874429	NS	NS	Substitution - Missense
c.827C>T; p.P276L; 23:136875124-136875124	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.111A>G; p.V37V; 23:136879122-136879122	liver	carcinoma	Substitution - coding silent
c.587G>A; p.R196K; 23:136875540-136875540	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.808C>T; p.R270C; 23:136875143-136875143	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.583C>T; p.R195*; 23:136875544-136875544	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1158A>G; p.G386G; 23:136874160-136874160	central_nervous_system; brain	glioma	Substitution - coding silent
c.775G>A; p.G259R; 23:136875265-136875265	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.268G>A; p.E90K; 23:136878035-136878035	skin	malignant_melanoma	Substitution - Missense
c.793G>A; p.G265R; 23:136875158-136875158	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.950G>A; p.R317H; 23:136874368-136874368	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.13G>T; p.D5Y; 23:136879415-136879415	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.13G>T; p.D5Y; 23:136879415-136879415	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.13G>T; p.D5Y; 23:136879415-136879415	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1170A>T; p.R390S; 23:136874148-136874148	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	thyroid	other; neoplasm	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	pancreas	other; adenoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	urinary_tract; bladder	carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1018G>A; p.D340N; 23:136874300-136874300	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27G>C; p.K9N; 23:136879401-136879401	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605G>A; p.R202H; 23:136875522-136875522	breast	carcinoma	Substitution - Missense
c.382C>T; p.H128Y; 23:136877921-136877921	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.155C>A; p.A52D; 23:136879078-136879078	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	thyroid	other; neoplasm	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	liver	carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971G>C; p.R324P; 23:136874347-136874347	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.730C>T; p.R244C; 23:136875310-136875310	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614T>A; p.V205D; 23:136875513-136875513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	liver	carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	thyroid	other; neoplasm	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	liver	carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.499C>G; p.P167A; 23:136876545-136876545	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.23G>T; p.G8V; 23:136879405-136879405	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142delT; p.S48fs*22; 23:136879091-136879091	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1014T>C; p.G338G; 23:136874304-136874304	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.642T>A; p.Y214*; 23:136875485-136875485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.642T>A; p.Y214*; 23:136875485-136875485	liver	carcinoma	Substitution - Nonsense
c.642T>A; p.Y214*; 23:136875485-136875485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.642T>A; p.Y214*; 23:136875485-136875485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.642T>A; p.Y214*; 23:136875485-136875485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.642T>A; p.Y214*; 23:136875485-136875485	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.343G>A; p.G115R; 23:136877960-136877960	central_nervous_system; brainstem	glioma; astrocytoma_Grade_II	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	thyroid	other; neoplasm	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	prostate	adenoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	liver	carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	thyroid	other; neoplasm	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343G>A; p.G115R; 23:136877960-136877960	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.903G>C; p.P301P; 23:136874415-136874415	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.596T>C; p.L199P; 23:136875531-136875531	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.368C>T; p.P123L; 23:136877935-136877935	skin	malignant_melanoma	Substitution - Missense
c.176C>A; p.P59Q; 23:136879057-136879057	skin	malignant_melanoma	Substitution - Missense
c.934G>A; p.D312N; 23:136874384-136874384	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.934G>A; p.D312N; 23:136874384-136874384	breast	carcinoma	Substitution - Missense
c.934G>A; p.D312N; 23:136874384-136874384	pancreas	carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	thyroid	other; neoplasm	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	urinary_tract; bladder	carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1_2insAA; p.?; 23:136879426-136879427	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1_2insAA; p.?; 23:136879426-136879427	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Unknown
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.G158V; 23:136876571-136876571	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	breast	carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.242T>G; p.V81G; 23:136878061-136878061	breast	carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.A78T; 23:136878071-136878071	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1_2insA; p.?; 23:136879426-136879427	breast	carcinoma	Unknown
c.491G>C; p.R164T; 23:136876553-136876553	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874C>T; p.R292C; 23:136874444-136874444	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1_2insA; p.?; 23:136879426-136879427	skin; sole	malignant_melanoma; acral_lentiginous	Unknown
c.669A>G; p.R223R; 23:136875371-136875371	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.669A>G; p.R223R; 23:136875371-136875371	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1069T>C; p.Y357H; 23:136874249-136874249	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.559A>G; p.R187G; 23:136875568-136875568	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1066G>T; p.G356W; 23:136874252-136874252	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1066G>T; p.G356W; 23:136874252-136874252	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559A>G; p.R187G; 23:136875568-136875568	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.559A>G; p.R187G; 23:136875568-136875568	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.559A>G; p.R187G; 23:136875568-136875568	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.570T>C; p.Y190Y; 23:136875557-136875557	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.698A>C; p.D233A; 23:136875342-136875342	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.698A>C; p.D233A; 23:136875342-136875342	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.400T>C; p.Y134H; 23:136876644-136876644	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.181G>C; p.D61H; 23:136879052-136879052	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.1159G>A; p.G387S; 23:136874159-136874159	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.181G>C; p.D61H; 23:136879052-136879052	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.584G>A; p.R195Q; 23:136875543-136875543	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.120G>A; p.M40I; 23:136879113-136879113	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.962G>T; p.G321V; 23:136874356-136874356	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.796T>C; p.Y266H; 23:136875155-136875155	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.374G>T; p.R125L; 23:136877929-136877929	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.515G>A; p.R172H; 23:136876529-136876529	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.906_907insCC; p.S303fs*>90; 23:136874411-136874412	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.180A>G; p.A60A; 23:136879053-136879053	breast	carcinoma	Substitution - coding silent
c.1157delG; p.G386fs*>6; 23:136874161-136874161	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.413T>C; p.F138S; 23:136876631-136876631	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.316_317insTT; p.P106fs*32; 23:136877986-136877987	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.179C>A; p.A60E; 23:136879054-136879054	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.956G>A; p.G319E; 23:136874362-136874362	skin	malignant_melanoma	Substitution - Missense
c.8A>G; p.E3G; 23:136879420-136879420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.956G>A; p.G319E; 23:136874362-136874362	skin	malignant_melanoma	Substitution - Missense
c.956G>A; p.G319E; 23:136874362-136874362	skin	malignant_melanoma	Substitution - Missense
c.851C>T; p.S284L; 23:136875100-136875100	oesophagus	carcinoma	Substitution - Missense
c.390T>C; p.D130D; 23:136876654-136876654	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	liver	carcinoma	Substitution - Missense
c.304A>C; p.S102R; 23:136877999-136877999	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	liver	carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212G>C; p.G71A; 23:136879021-136879021	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1010G>A; p.S337N; 23:136874308-136874308	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.22G>T; p.G8*; 23:136879406-136879406	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.572G>A; p.G191E; 23:136875555-136875555	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]