Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3428

Name

IFI16

Synonymous

interferon, gamma-inducible protein 16;IFI16;interferon, gamma-inducible protein 16

Definition

gamma-interferon-inducible protein 16|interferon-gamma induced protein IFI 16|interferon-inducible myeloid differentiation transcriptional activator

Position

1q22

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.13.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1190A>G; p.N397S; 1:159032552-159032552

 breastcarcinomaSubstitution - Missense

c.1838C>T; p.A613V; 1:159052019-159052019

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.878A>C; p.K293T; 1:159018557-159018557

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1725C>G; p.A575A; 1:159051906-159051906

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.387_388insA; p.S132fs*12; 1:159016538-159016539

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IVInsertion - Frameshift

c.1675G>A; p.V559I; 1:159051856-159051856

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.661C>G; p.P221A; 1:159018340-159018340

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.247delA; p.E85fs*3; 1:159014927-159014927

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1435G>A; p.E479K; 1:159045402-159045402

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1600G>T; p.V534L; 1:159051781-159051781

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1843G>A; p.V615I; 1:159052024-159052024

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1449C>A; p.H483Q; 1:159045416-159045416

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.590G>A; p.R197K; 1:159018269-159018269

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.1225C>A; p.R409S; 1:159032587-159032587

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.394T>C; p.S132P; 1:159016545-159016545

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.919C>G; p.L307V; 1:159018598-159018598

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.92A>C; p.N31T; 1:159014772-159014772

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.287G>T; p.R96I; 1:159015893-159015893

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1044A>C; p.T348T; 1:159020412-159020412

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.510G>T; p.K170N; 1:159016661-159016661

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1103G>A; p.R368Q; 1:159020471-159020471

 thyroidcarcinomaSubstitution - Missense

c.1320C>A; p.F440L; 1:159032682-159032682

 prostatecarcinomaSubstitution - Missense

c.146C>T; p.A49V; 1:159014826-159014826

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1735_1736delTA; p.Y579fs*17; 1:159051916-159051917

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaDeletion - Frameshift

c.1167_1168insA; p.T392fs*7; 1:159032529-159032530

 pancreascarcinoma; ductal_carcinomaInsertion - Frameshift

c.967C>T; p.H323Y; 1:159018646-159018646

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.2074G>T; p.G692W; 1:159053689-159053689

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.599T>C; p.L200P; 1:159018278-159018278

 livercarcinomaSubstitution - Missense

c.717C>A; p.F239L; 1:159018396-159018396

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1245A>G; p.S415S; 1:159032607-159032607

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.315T>C; p.T105T; 1:159015921-159015921

 breastcarcinomaSubstitution - coding silent

c.1656T>C; p.N552N; 1:159051837-159051837

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1168A>T; p.K390*; 1:159032530-159032530

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.2084G>C; p.R695T; 1:159053699-159053699

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1003G>A; p.E335K; 1:159020371-159020371

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1134G>T; p.L378L; 1:159020502-159020502

 livercarcinomaSubstitution - coding silent

c.1022G>A; p.G341E; 1:159020390-159020390

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.633T>A; p.S211R; 1:159018312-159018312

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.114A>T; p.K38N; 1:159014794-159014794

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2037C>T; p.L679L; 1:159053652-159053652

 skinmalignant_melanomaSubstitution - coding silent

c.68G>A; p.R23K; 1:159014748-159014748

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.46G>T; p.V16F; 1:159014726-159014726

 breastcarcinomaSubstitution - Missense

c.572G>A; p.C191Y; 1:159018251-159018251

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.986A>G; p.Q329R; 1:159020354-159020354

 livercarcinomaSubstitution - Missense

c.1458G>T; p.Q486H; 1:159045425-159045425

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.986A>G; p.Q329R; 1:159020354-159020354

 livercarcinomaSubstitution - Missense

c.1822G>T; p.G608*; 1:159052003-159052003

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.919C>A; p.L307I; 1:159018598-159018598

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.45G>T; p.E15D; 1:159014725-159014725

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.814G>A; p.E272K; 1:159018493-159018493

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2067G>A; p.G689G; 1:159053682-159053682

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.361G>C; p.E121Q; 1:159015967-159015967

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.913G>A; p.D305N; 1:159018592-159018592

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.526C>T; p.P176S; 1:159016677-159016677

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1802G>A; p.R601Q; 1:159051983-159051983

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2109+6A>T; p.?; 1:159053730-159053730

 livercarcinomaUnknown

c.376G>T; p.A126S; 1:159015982-159015982

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1475C>A; p.P492Q; 1:159045442-159045442

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.376G>T; p.A126S; 1:159015982-159015982

 livercarcinomaSubstitution - Missense

c.2109+6A>T; p.?; 1:159053730-159053730

 livercarcinomaUnknown

c.1475C>A; p.P492Q; 1:159045442-159045442

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1661T>C; p.V554A; 1:159051842-159051842

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1554G>A; p.Q518Q; 1:159051735-159051735

 breastcarcinomaSubstitution - coding silent

c.1554G>A; p.Q518Q; 1:159051735-159051735

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1210C>G; p.L404V; 1:159032572-159032572

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1994_1999delGACTGA; p.R665_T667>P; 1:159053609-159053614

 prostatecarcinomaComplex - deletion inframe

c.658A>G; p.T220A; 1:159018337-159018337

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.211G>A; p.D71N; 1:159014891-159014891

 pancreascarcinomaSubstitution - Missense

c.6delA; p.K4fs*8; 1:159014686-159014686

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1061delT; p.I354fs*25; 1:159020429-159020429

 central_nervous_system; braingliomaDeletion - Frameshift

c.1885A>C; p.S629R; 1:159052066-159052066

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.6delA; p.K4fs*8; 1:159014686-159014686

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.785C>T; p.S262L; 1:159018464-159018464

 central_nervous_system; braingliomaSubstitution - Missense

c.1954C>G; p.Q652E; 1:159053569-159053569

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.897G>A; p.K299K; 1:159018576-159018576

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.575A>C; p.Q192P; 1:159018254-159018254

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1209G>C; p.K403N; 1:159032571-159032571

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2167A>T; p.T723S; 1:159054878-159054878

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.435C>T; p.S145S; 1:159016586-159016586

 oesophaguscarcinomaSubstitution - coding silent

c.1086C>T; p.L362L; 1:159020454-159020454

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1518_1519TG>CT; p.E507*; 1:159051699-159051700

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.268A>C; p.K90Q; 1:159015874-159015874

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1099T>G; p.F367V; 1:159020467-159020467

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.362A>G; p.E121G; 1:159015968-159015968

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1872A>G; p.S624S; 1:159052053-159052053

 breastcarcinomaSubstitution - coding silent

c.620T>C; p.V207A; 1:159018299-159018299

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.885C>T; p.I295I; 1:159018564-159018564

 skinmalignant_melanomaSubstitution - coding silent

c.346A>C; p.K116Q; 1:159015952-159015952

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1489T>G; p.L497V; 1:159045456-159045456

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2009A>C; p.N670T; 1:159053624-159053624

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.265G>C; p.V89L; 1:159014945-159014945

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1154T>G; p.F385C; 1:159020522-159020522

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.100A>T; p.K34*; 1:159014780-159014780

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.606A>G; p.K202K; 1:159018285-159018285

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2115C>G; p.I705M; 1:159054826-159054826

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.478T>A; p.S160T; 1:159016629-159016629

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1214C>T; p.P405L; 1:159032576-159032576

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1102C>T; p.R368*; 1:159020470-159020470

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.717C>T; p.F239F; 1:159018396-159018396

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1623G>T; p.K541N; 1:159051804-159051804

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1921A>C; p.N641H; 1:159053536-159053536

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.539C>A; p.S180Y; 1:159016690-159016690

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1339G>T; p.D447Y; 1:159045306-159045306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.427A>T; p.K143*; 1:159016578-159016578

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Nonsense

c.1745G>A; p.R582H; 1:159051926-159051926

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.672_673insA; p.I227fs*42; 1:159018351-159018352

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1745G>A; p.R582H; 1:159051926-159051926

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.94G>A; p.D32N; 1:159014774-159014774

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1669G>C; p.V557L; 1:159051850-159051850

 breastcarcinomaSubstitution - Missense

c.417C>A; p.P139P; 1:159016568-159016568

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.952G>T; p.G318W; 1:159018631-159018631

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1277T>G; p.L426R; 1:159032639-159032639

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1277T>G; p.L426R; 1:159032639-159032639

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1089A>G; p.Q363Q; 1:159020457-159020457

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1089A>G; p.Q363Q; 1:159020457-159020457

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1277T>G; p.L426R; 1:159032639-159032639

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1089A>G; p.Q363Q; 1:159020457-159020457

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.2014G>T; p.E672*; 1:159053629-159053629

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1240C>A; p.P414T; 1:159032602-159032602

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.246_247insA; p.E85fs*34; 1:159014926-159014927

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.982A>T; p.N328Y; 1:159020350-159020350

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.208G>A; p.E70K; 1:159014888-159014888

 large_intestine; caecumadenomaSubstitution - Missense

c.618A>G; p.I206M; 1:159018297-159018297

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.62A>T; p.H21L; 1:159014742-159014742

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.291G>C; p.K97N; 1:159015897-159015897

 breastcarcinomaSubstitution - Missense

c.611C>A; p.P204Q; 1:159018290-159018290

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1450A>C; p.T484P; 1:159045417-159045417

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2058G>A; p.P686P; 1:159053673-159053673

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1345A>C; p.I449L; 1:159045312-159045312

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1237T>A; p.Y413N; 1:159032599-159032599

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1530A>C; p.E510D; 1:159051711-159051711

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1530A>C; p.E510D; 1:159051711-159051711

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1530A>C; p.E510D; 1:159051711-159051711

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1209G>A; p.K403K; 1:159032571-159032571

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1842C>T; p.S614S; 1:159052023-159052023

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1310C>T; p.S437F; 1:159032672-159032672

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1873C>A; p.Q625K; 1:159052054-159052054

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1345A>G; p.I449V; 1:159045312-159045312

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.673_674insA; p.I227fs*42; 1:159018352-159018353

 stomachcarcinoma; intestinal_adenocarcinomaInsertion - Frameshift

c.1801C>T; p.R601*; 1:159051982-159051982

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1801C>T; p.R601*; 1:159051982-159051982

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1786G>A; p.D596N; 1:159051967-159051967

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.471C>G; p.A157A; 1:159016622-159016622

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.392A>C; p.K131T; 1:159016543-159016543

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1253G>A; p.S418N; 1:159032615-159032615

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2052G>T; p.L684F; 1:159053667-159053667

 livercarcinomaSubstitution - Missense

c.2052G>T; p.L684F; 1:159053667-159053667

 livercarcinomaSubstitution - Missense

c.2082G>C; p.L694F; 1:159053697-159053697

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1928G>T; p.R643M; 1:159053543-159053543

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1585G>A; p.A529T; 1:159051766-159051766

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1673A>T; p.K558M; 1:159051854-159051854

 breastcarcinomaSubstitution - Missense

c.1585G>A; p.A529T; 1:159051766-159051766

 pancreascarcinomaSubstitution - Missense

c.1585G>A; p.A529T; 1:159051766-159051766

 pancreascarcinomaSubstitution - Missense

c.1585G>A; p.A529T; 1:159051766-159051766

 pancreascarcinomaSubstitution - Missense

c.1256C>A; p.T419K; 1:159032618-159032618

 livercarcinomaSubstitution - Missense

c.1256C>A; p.T419K; 1:159032618-159032618

 livercarcinomaSubstitution - Missense

c.409G>T; p.A137S; 1:159016560-159016560

 prostatecarcinomaSubstitution - Missense

c.528A>C; p.P176P; 1:159016679-159016679

 breastcarcinomaSubstitution - coding silent

c.830C>A; p.S277Y; 1:159018509-159018509

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1406G>A; p.G469E; 1:159045373-159045373

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.211G>T; p.D71Y; 1:159014891-159014891

 breastcarcinomaSubstitution - Missense

c.207C>T; p.F69F; 1:159014887-159014887

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1050A>G; p.Q350Q; 1:159020418-159020418

 breastcarcinomaSubstitution - coding silent

')