Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	3963
Name	LGALS7
Synonymous	lectin, galactoside-binding, soluble, 7;LGALS7;lectin, galactoside-binding, soluble, 7
Definition	galectin 7\|galectin-7
Position	19q13.2
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

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We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.

The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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Loss of Function mutations compare to missense mutation.

The ratio of the loss-of-function mutations over missense mutations is 0.00.

The copy number variations for various cancers

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There is no record for LGALS7

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.156delC; p.R54fs*80; 19:38790749-38790749	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.222G>A; p.E74E; 19:38790815-38790815	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.132C>T; p.G44G; 19:38790725-38790725	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.173C>T; p.S58L; 19:38790766-38790766	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.118G>T; p.G40W; 19:38790711-38790711	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.142G>A; p.A48T; 19:38790735-38790735	stomach	carcinoma; adenocarcinoma	Substitution - Missense

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