| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4814 |
Name | NINJ1 |
Synonymous | ninjurin 1;NINJ1;ninjurin 1 |
Definition | nerve injury-induced protein 1|nerve injury-induced protein-1|ninjurin-1 |
Position | 9q22 |
Gene Type | protein-coding |
Mutation summary: | Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72 |
Mutation summary in protein domains | Top |
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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers | Top |
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Loss of Function mutations compare to missense mutations | Top |
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| The ratio of the loss-of-function mutations over missense mutations is 0.00. |
The copy number variations for various cancers | Top |
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The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
COSMIC somatic mutation [Top] | |||
|
Mutation (CDS; AA; Chr) |
Site |
Histology |
Mutation Type |
|---|---|---|---|
c.454C>T; p.Q152*; 9:93124913-93124913 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.423C>A; p.V141V; 9:93124944-93124944 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.280G>A; p.V94M; 9:93126434-93126434 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.278G>A; p.G93D; 9:93126436-93126436 |
pancreas | carcinoma | Substitution - Missense |
c.278G>A; p.G93D; 9:93126436-93126436 |
pancreas | carcinoma | Substitution - Missense |
c.237C>T; p.P79P; 9:93126477-93126477 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.422T>C; p.V141A; 9:93124945-93124945 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.410C>T; p.T137M; 9:93124957-93124957 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.103C>T; p.P35S; 9:93126611-93126611 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.90C>T; p.G30G; 9:93126624-93126624 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.236C>A; p.P79H; 9:93126478-93126478 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.138C>T; p.S46S; 9:93126576-93126576 |
breast | carcinoma | Substitution - coding silent |
c.304+2T>C; p.?; 9:93126408-93126408 |
pancreas | carcinoma | Unknown |
c.304+2T>C; p.?; 9:93126408-93126408 |
pancreas | carcinoma | Unknown |
c.64C>A; p.P22T; 9:93134154-93134154 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Substitution - Missense |
c.337G>A; p.A113T; 9:93125030-93125030 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.112G>A; p.V38M; 9:93126602-93126602 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.181G>A; p.A61T; 9:93126533-93126533 |
skin | malignant_melanoma | Substitution - Missense |
c.224C>A; p.A75D; 9:93126490-93126490 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.223G>A; p.A75T; 9:93126491-93126491 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.329C>A; p.A110D; 9:93125038-93125038 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.421G>A; p.V141I; 9:93124946-93124946 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - Missense |