Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

54971

Name

BANP

Synonymous

BTG3 associated nuclear protein;BANP;BTG3 associated nuclear protein

Definition

BEN domain-containing protein 1|protein BANP|scaffold/matrix-associated region-1-binding protein

Position

16q24

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

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Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.06.

The copy number variations for various cancers

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The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.56G>C; p.S19T; 16:87975171-87975171

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.428A>G; p.H143R; 16:88006155-88006155

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.992C>T; p.P331L; 16:88033154-88033154

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.408G>A; p.P136P; 16:88006135-88006135

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.970C>T; p.P324S; 16:88033132-88033132

 skinmalignant_melanomaSubstitution - Missense

c.230C>T; p.A77V; 16:87984127-87984127

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.452A>G; p.E151G; 16:88006179-88006179

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.662C>T; p.A221V; 16:88018551-88018551

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1363C>T; p.L455L; 16:88076614-88076614

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.989A>T; p.Q330L; 16:88033151-88033151

 oesophaguscarcinomaSubstitution - Missense

c.813C>T; p.S271S; 16:88027517-88027517

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.722G>A; p.G241E; 16:88018611-88018611

 pancreascarcinomaSubstitution - Missense

c.306C>T; p.V102V; 16:87984203-87984203

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.485C>T; p.A162V; 16:88006212-88006212

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.635C>T; p.T212I; 16:88018524-88018524

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.857C>T; p.T286M; 16:88027561-88027561

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.1021G>A; p.A341T; 16:88033183-88033183

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.696G>A; p.E232E; 16:88018585-88018585

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.908C>A; p.S303*; 16:88027612-88027612

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1084-2G>A; p.?; 16:88035321-88035321

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.320G>T; p.G107V; 16:87984217-87984217

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.802A>G; p.I268V; 16:88027506-88027506

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.950C>T; p.P317L; 16:88033112-88033112

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.624G>A; p.L208L; 16:88018513-88018513

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1014G>T; p.L338L; 16:88033176-88033176

 livercarcinomaSubstitution - coding silent

c.1014G>T; p.L338L; 16:88033176-88033176

 livercarcinomaSubstitution - coding silent

c.1345G>A; p.E449K; 16:88076596-88076596

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.691C>T; p.R231C; 16:88018580-88018580

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1060G>A; p.G354R; 16:88033222-88033222

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1060G>A; p.G354R; 16:88033222-88033222

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1017C>A; p.H339Q; 16:88033179-88033179

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1219G>A; p.A407T; 16:88072093-88072093

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1219G>A; p.A407T; 16:88072093-88072093

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1345G>C; p.E449Q; 16:88076596-88076596

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.1176C>T; p.H392H; 16:88037993-88037993

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.593T>C; p.V198A; 16:88018482-88018482

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.593T>C; p.V198A; 16:88018482-88018482

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.973G>A; p.A325T; 16:88033135-88033135

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.910C>T; p.R304W; 16:88027614-88027614

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.963C>T; p.T321T; 16:88033125-88033125

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1195-6C>T; p.?; 16:88072063-88072063

 pancreascarcinomaUnknown

c.1077G>T; p.V359V; 16:88033239-88033239

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1019A>G; p.Y340C; 16:88033181-88033181

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.122G>A; p.R41H; 16:87981087-87981087

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.918G>A; p.T306T; 16:88027622-88027622

 lungcarcinoma; small_cell_carcinomaSubstitution - coding silent

c.1309C>T; p.P437S; 16:88072183-88072183

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1005G>A; p.P335P; 16:88033167-88033167

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1122delG; p.E376fs*30; 16:88035361-88035361

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.779-1G>C; p.?; 16:88027482-88027482

 prostatecarcinoma; adenocarcinomaUnknown

c.381G>T; p.R127R; 16:88006108-88006108

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.429C>G; p.H143Q; 16:88006156-88006156

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.444C>T; p.S148S; 16:88006171-88006171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.629T>C; p.I210T; 16:88018518-88018518

 skinmalignant_melanomaSubstitution - Missense

c.961A>G; p.T321A; 16:88033123-88033123

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1003C>T; p.P335S; 16:88033165-88033165

 skinmalignant_melanomaSubstitution - Missense

c.105C>T; p.D35D; 16:87981070-87981070

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.105C>T; p.D35D; 16:87981070-87981070

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1246G>C; p.A416P; 16:88072120-88072120

 thyroidother; neoplasmSubstitution - Missense

c.538G>C; p.E180Q; 16:88006265-88006265

 ovaryother; neoplasmSubstitution - Missense

c.595C>T; p.R199C; 16:88018484-88018484

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.271C>G; p.L91V; 16:87984168-87984168

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.666C>A; p.L222L; 16:88018555-88018555

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.666C>A; p.L222L; 16:88018555-88018555

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1390delG; p.A465fs*>5; 16:88076641-88076641

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.651C>T; p.A217A; 16:88018540-88018540

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.651C>T; p.A217A; 16:88018540-88018540

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.49G>C; p.D17H; 16:87975164-87975164

 NSNSSubstitution - Missense

c.648G>A; p.T216T; 16:88018537-88018537

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.868C>T; p.R290C; 16:88027572-88027572

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1004C>T; p.P335L; 16:88033166-88033166

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1262C>T; p.S421L; 16:88072136-88072136

 skinmalignant_melanomaSubstitution - Missense

c.422G>T; p.S141I; 16:88006149-88006149

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.422G>T; p.S141I; 16:88006149-88006149

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.422G>T; p.S141I; 16:88006149-88006149

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.422G>T; p.S141I; 16:88006149-88006149

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.445G>A; p.G149S; 16:88006172-88006172

 pancreascarcinomaSubstitution - Missense

c.145C>A; p.Q49K; 16:87981110-87981110

 breastcarcinomaSubstitution - Missense

c.133G>T; p.E45*; 16:87981098-87981098

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.231C>T; p.A77A; 16:87984128-87984128

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.601G>A; p.A201T; 16:88018490-88018490

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.364G>T; p.A122S; 16:88006091-88006091

 skinmalignant_melanomaSubstitution - Missense

c.736G>A; p.G246R; 16:88018625-88018625

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1245G>A; p.A415A; 16:88072119-88072119

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1245G>A; p.A415A; 16:88072119-88072119

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1245G>A; p.A415A; 16:88072119-88072119

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1245G>A; p.A415A; 16:88072119-88072119

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1245G>A; p.A415A; 16:88072119-88072119

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1245G>A; p.A415A; 16:88072119-88072119

 thyroidother; neoplasmSubstitution - coding silent

c.460G>A; p.D154N; 16:88006187-88006187

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.534G>A; p.S178S; 16:88006261-88006261

 pancreascarcinomaSubstitution - coding silent

c.523A>G; p.T175A; 16:88006250-88006250

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

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