Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6134

Name

RPL10

Synonymous

ribosomal protein L10;RPL10;ribosomal protein L10

Definition

60S ribosomal protein L10|Wilms tumor-related protein|laminin receptor homolog|tumor suppressor QM

Position

Xq28

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.00.

The copy number variations for various cancers

Top

There is no record for RPL10

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.16G>A; p.A6T; 23:154398535-154398535

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.209T>C; p.I70T; 23:154399821-154399821

 skinmalignant_melanomaSubstitution - Missense

c.470T>C; p.F157S; 23:154400604-154400604

 breastcarcinomaSubstitution - Missense

c.268C>T; p.R90W; 23:154399880-154399880

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.58T>C; p.S20P; 23:154399372-154399372

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.58T>C; p.S20P; 23:154399372-154399372

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.368A>C; p.Q123P; 23:154400502-154400502

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.4G>A; p.G2S; 23:154398523-154398523

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.457C>T; p.R153C; 23:154400591-154400591

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.457C>T; p.R153C; 23:154400591-154400591

 pancreascarcinomaSubstitution - Missense

c.121G>A; p.A41T; 23:154399525-154399525

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.121G>A; p.A41T; 23:154399525-154399525

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.243C>T; p.G81G; 23:154399855-154399855

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.166G>A; p.E56K; 23:154399570-154399570

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.411C>T; p.S137S; 23:154400545-154400545

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.559G>A; p.E187K; 23:154400768-154400768

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.279C>T; p.P93P; 23:154399891-154399891

 skinmalignant_melanomaSubstitution - coding silent

c.292C>T; p.R98C; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.69C>T; p.C23C; 23:154399383-154399383

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.355T>C; p.F119L; 23:154400489-154400489

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.3G>T; p.M1I; 23:154398522-154398522

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.501C>T; p.I167I; 23:154400710-154400710

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.271C>T; p.L91F; 23:154399883-154399883

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.96C>A; p.R32R; 23:154399500-154399500

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.550A>C; p.M184L; 23:154400759-154400759

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.115delA; p.K40fs*38; 23:154399519-154399519

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.61C>T; p.R21C; 23:154399375-154399375

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.119A>G; p.K40R; 23:154399523-154399523

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.135G>A; p.E45E; 23:154399539-154399539

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.291C>G; p.I97M; 23:154399903-154399903

 breastcarcinomaSubstitution - Missense

c.134A>G; p.E45G; 23:154399538-154399538

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.8G>A; p.R3H; 23:154398527-154398527

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.440A>G; p.H147R; 23:154400574-154400574

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.349G>A; p.G117S; 23:154400483-154400483

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.296T>C; p.I99T; 23:154399908-154399908

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.308T>C; p.L103S; 23:154399920-154399920

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.399A>G; p.Q133Q; 23:154400533-154400533

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.444G>C; p.V148V; 23:154400578-154400578

 breastcarcinomaSubstitution - coding silent

c.263G>C; p.R88P; 23:154399875-154399875

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.507G>T; p.K169N; 23:154400716-154400716

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.478C>T; p.P160S; 23:154400612-154400612

 skinmalignant_melanomaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.292C>A; p.R98S; 23:154399904-154399904

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.275A>C; p.H92P; 23:154399887-154399887

 breastcarcinomaSubstitution - Missense

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