Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7545

Name

ZIC1

Synonymous

Zic family member 1;ZIC1;Zic family member 1

Definition

Zic family member 1 (odd-paired homolog, Drosophila)|Zinc finger protein of the cerebellum 1|zinc finger protein 201|zinc finger protein ZIC 1

Position

3q24

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.04.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.62G>A; p.R21H; 3:147410174-147410174

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.881G>A; p.R294H; 3:147410993-147410993

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.600G>T; p.M200I; 3:147410712-147410712

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.265T>A; p.Y89N; 3:147410377-147410377

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.187G>A; p.A63T; 3:147410299-147410299

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.187G>A; p.A63T; 3:147410299-147410299

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1002C>A; p.C334*; 3:147412537-147412537

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.291G>A; p.T97T; 3:147410403-147410403

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.160C>T; p.H54Y; 3:147410272-147410272

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1227C>A; p.I409I; 3:147413434-147413434

 livercarcinomaSubstitution - coding silent

c.1029C>T; p.F343F; 3:147412564-147412564

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1029C>T; p.F343F; 3:147412564-147412564

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1154A>T; p.E385V; 3:147413361-147413361

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.652C>A; p.R218S; 3:147410764-147410764

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.651G>A; p.M217I; 3:147410763-147410763

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1335G>A; p.W445*; 3:147413542-147413542

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.761C>T; p.T254M; 3:147410873-147410873

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.408C>A; p.D136E; 3:147410520-147410520

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.411C>A; p.A137A; 3:147410523-147410523

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.57G>A; p.A19A; 3:147410169-147410169

 central_nervous_system; braingliomaSubstitution - coding silent

c.57G>A; p.A19A; 3:147410169-147410169

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.57G>A; p.A19A; 3:147410169-147410169

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1334G>T; p.W445L; 3:147413541-147413541

 thyroidother; neoplasmSubstitution - Missense

c.1071G>A; p.T357T; 3:147412606-147412606

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.983G>C; p.G328A; 3:147412518-147412518

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.1197T>C; p.S399S; 3:147413404-147413404

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.706G>A; p.A236T; 3:147410818-147410818

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1274C>A; p.S425Y; 3:147413481-147413481

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.384C>T; p.F128F; 3:147410496-147410496

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.158C>T; p.S53L; 3:147410270-147410270

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1282G>A; p.A428T; 3:147413489-147413489

 prostateadenomaSubstitution - Missense

c.1330G>A; p.E444K; 3:147413537-147413537

 skinmalignant_melanomaSubstitution - Missense

c.570T>C; p.A190A; 3:147410682-147410682

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.903C>A; p.P301P; 3:147411015-147411015

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1196C>G; p.S399C; 3:147413403-147413403

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1330G>A; p.E444K; 3:147413537-147413537

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1298C>A; p.A433D; 3:147413505-147413505

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1330G>A; p.E444K; 3:147413537-147413537

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1017T>C; p.C339C; 3:147412552-147412552

 endometriumcarcinoma; serous_carcinomaSubstitution - coding silent

c.159G>A; p.S53S; 3:147410271-147410271

 thyroidcarcinomaSubstitution - coding silent

c.622C>A; p.H208N; 3:147410734-147410734

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.834C>T; p.R278R; 3:147410946-147410946

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.95A>T; p.D32V; 3:147410207-147410207

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.622C>A; p.H208N; 3:147410734-147410734

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1102G>A; p.D368N; 3:147412637-147412637

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1102G>A; p.D368N; 3:147412637-147412637

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1277C>T; p.S426F; 3:147413484-147413484

 skinmalignant_melanomaSubstitution - Missense

c.894C>T; p.G298G; 3:147411006-147411006

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.73G>A; p.A25T; 3:147410185-147410185

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1102G>A; p.D368N; 3:147412637-147412637

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.695C>A; p.P232H; 3:147410807-147410807

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1041C>G; p.S347R; 3:147412576-147412576

 skinmalignant_melanomaSubstitution - Missense

c.1009G>C; p.E337Q; 3:147412544-147412544

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.389G>C; p.G130A; 3:147410501-147410501

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1314C>A; p.L438L; 3:147413521-147413521

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1011G>A; p.E337E; 3:147412546-147412546

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1011G>A; p.E337E; 3:147412546-147412546

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.412G>A; p.A138T; 3:147410524-147410524

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1011G>A; p.E337E; 3:147412546-147412546

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1310C>T; p.A437V; 3:147413517-147413517

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.152C>A; p.P51H; 3:147410264-147410264

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1045C>T; p.R349C; 3:147412580-147412580

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.619C>T; p.H207Y; 3:147410731-147410731

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.603C>T; p.N201N; 3:147410715-147410715

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.619C>T; p.H207Y; 3:147410731-147410731

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.571G>T; p.A191S; 3:147410683-147410683

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.397G>A; p.G133S; 3:147410509-147410509

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.383T>A; p.F128Y; 3:147410495-147410495

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.192C>T; p.F64F; 3:147410304-147410304

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.879C>A; p.I293I; 3:147410991-147410991

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.980C>A; p.T327K; 3:147411092-147411092

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.792G>A; p.P264P; 3:147410904-147410904

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.616G>A; p.A206T; 3:147410728-147410728

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1216C>A; p.P406T; 3:147413423-147413423

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.915C>T; p.P305P; 3:147411027-147411027

 oesophaguscarcinomaSubstitution - coding silent

c.423C>G; p.L141L; 3:147410535-147410535

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1127C>T; p.S376L; 3:147412662-147412662

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.507G>A; p.G169G; 3:147410619-147410619

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.150C>A; p.N50K; 3:147410262-147410262

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1042G>A; p.D348N; 3:147412577-147412577

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.576G>A; p.P192P; 3:147410688-147410688

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.576G>A; p.P192P; 3:147410688-147410688

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.576G>A; p.P192P; 3:147410688-147410688

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.343A>T; p.S115C; 3:147410455-147410455

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1215G>A; p.T405T; 3:147413422-147413422

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.551C>T; p.P184L; 3:147410663-147410663

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.1167G>T; p.Q389H; 3:147413374-147413374

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1036A>C; p.S346R; 3:147412571-147412571

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.763C>A; p.H255N; 3:147410875-147410875

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.408C>T; p.D136D; 3:147410520-147410520

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.804T>C; p.N268N; 3:147410916-147410916

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.76G>A; p.G26S; 3:147410188-147410188

 pancreascarcinomaSubstitution - Missense

c.385G>T; p.G129W; 3:147410497-147410497

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1227C>T; p.I409I; 3:147413434-147413434

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.10G>A; p.D4N; 3:147410122-147410122

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.778C>A; p.H260N; 3:147410890-147410890

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.313C>A; p.R105R; 3:147410425-147410425

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.635C>A; p.A212D; 3:147410747-147410747

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.723G>A; p.S241S; 3:147410835-147410835

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.557C>T; p.S186L; 3:147410669-147410669

 breastcarcinomaSubstitution - Missense

c.465G>A; p.S155S; 3:147410577-147410577

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.713C>A; p.P238H; 3:147410825-147410825

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.557C>T; p.S186L; 3:147410669-147410669

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.713C>A; p.P238H; 3:147410825-147410825

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.899A>G; p.K300R; 3:147411011-147411011

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.96C>T; p.D32D; 3:147410208-147410208

 pancreascarcinomaSubstitution - coding silent

c.1307G>A; p.S436N; 3:147413514-147413514

 prostateadenomaSubstitution - Missense

c.189C>A; p.A63A; 3:147410301-147410301

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.995T>G; p.F332C; 3:147412530-147412530

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.136G>A; p.A46T; 3:147410248-147410248

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1096A>G; p.M366V; 3:147412631-147412631

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.55G>A; p.A19T; 3:147410167-147410167

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.96C>A; p.D32E; 3:147410208-147410208

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.96C>A; p.D32E; 3:147410208-147410208

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.116C>T; p.P39L; 3:147410228-147410228

 skinmalignant_melanomaSubstitution - Missense

c.1012G>A; p.G338S; 3:147412547-147412547

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1280C>T; p.S427F; 3:147413487-147413487

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1147-1G>T; p.?; 3:147413353-147413353

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.777G>T; p.E259D; 3:147410889-147410889

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.59C>T; p.S20F; 3:147410171-147410171

 kidneyother; neoplasmSubstitution - Missense

c.1109C>A; p.S370Y; 3:147412644-147412644

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.233G>T; p.G78V; 3:147410345-147410345

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.484C>A; p.Q162K; 3:147410596-147410596

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.503C>T; p.S168L; 3:147410615-147410615

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.971G>T; p.R324M; 3:147411083-147411083

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.455G>C; p.G152A; 3:147410567-147410567

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1288C>A; p.H430N; 3:147413495-147413495

 livercarcinomaSubstitution - Missense

c.1288C>A; p.H430N; 3:147413495-147413495

 livercarcinomaSubstitution - Missense

c.636C>T; p.A212A; 3:147410748-147410748

 prostatecarcinomaSubstitution - coding silent

c.745A>G; p.M249V; 3:147410857-147410857

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.154A>T; p.S52C; 3:147410266-147410266

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1087C>T; p.L363F; 3:147412622-147412622

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.846C>A; p.P282P; 3:147410958-147410958

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.999G>T; p.K333N; 3:147412534-147412534

 livercarcinomaSubstitution - Missense

c.76G>T; p.G26C; 3:147410188-147410188

 large_intestine; caecumadenomaSubstitution - Missense

c.526G>A; p.E176K; 3:147410638-147410638

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.91C>T; p.R31*; 3:147410203-147410203

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.941C>T; p.A314V; 3:147411053-147411053

 lung; left_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.617C>T; p.A206V; 3:147410729-147410729

 parathyroidcarcinomaSubstitution - Missense

c.975G>A; p.T325T; 3:147411087-147411087

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1080G>T; p.K360N; 3:147412615-147412615

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.912C>T; p.C304C; 3:147411024-147411024

 skinmalignant_melanomaSubstitution - coding silent

c.1046G>A; p.R349H; 3:147412581-147412581

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1046G>A; p.R349H; 3:147412581-147412581

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.295G>T; p.D99Y; 3:147410407-147410407

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1233T>A; p.S411S; 3:147413440-147413440

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.22C>G; p.Q8E; 3:147410134-147410134

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.634G>A; p.A212T; 3:147410746-147410746

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.335C>A; p.A112E; 3:147410447-147410447

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.209G>T; p.G70V; 3:147410321-147410321

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1147-2A>C; p.?; 3:147413352-147413352

 lung; right_upper_lobecarcinoma; adenocarcinomaUnknown

c.270C>T; p.S90S; 3:147410382-147410382

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1173G>A; p.S391S; 3:147413380-147413380

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.263C>T; p.S88F; 3:147410375-147410375

 skinmalignant_melanomaSubstitution - Missense

c.385G>A; p.G129R; 3:147410497-147410497

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1112A>G; p.Y371C; 3:147412647-147412647

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.796C>A; p.Q266K; 3:147410908-147410908

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1074C>A; p.S358R; 3:147412609-147412609

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.941C>G; p.A314G; 3:147411053-147411053

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.372G>A; p.S124S; 3:147410484-147410484

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1036A>G; p.S346G; 3:147412571-147412571

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.947C>G; p.S316C; 3:147411059-147411059

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.380G>T; p.G127V; 3:147410492-147410492

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1329C>G; p.N443K; 3:147413536-147413536

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.963C>G; p.I321M; 3:147411075-147411075

 breastcarcinomaSubstitution - Missense

c.1185G>A; p.P395P; 3:147413392-147413392

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.126C>T; p.D42D; 3:147410238-147410238

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1339G>A; p.V447I; 3:147413546-147413546

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1062C>G; p.H354Q; 3:147412597-147412597

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.883G>A; p.V295M; 3:147410995-147410995

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.943C>T; p.R315C; 3:147411055-147411055

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.943C>T; p.R315C; 3:147411055-147411055

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.677T>A; p.I226N; 3:147410789-147410789

 soft_tissue; blood_vesselangiosarcomaSubstitution - Missense

c.411C>T; p.A137A; 3:147410523-147410523

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.259G>A; p.G87S; 3:147410371-147410371

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.411C>T; p.A137A; 3:147410523-147410523

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1271C>T; p.P424L; 3:147413478-147413478

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.266A>C; p.Y89S; 3:147410378-147410378

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.861C>A; p.Y287*; 3:147410973-147410973

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.542T>A; p.V181E; 3:147410654-147410654

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.609C>T; p.N203N; 3:147410721-147410721

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.762G>T; p.T254T; 3:147410874-147410874

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.824A>T; p.E275V; 3:147410936-147410936

 stomachadenocarcinomaSubstitution - Missense

c.335C>T; p.A112V; 3:147410447-147410447

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.569C>A; p.A190D; 3:147410681-147410681

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1300G>A; p.G434S; 3:147413507-147413507

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.744C>A; p.T248T; 3:147410856-147410856

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.135C>T; p.G45G; 3:147410247-147410247

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1075G>A; p.D359N; 3:147412610-147412610

 skin; solemalignant_melanoma; acral_lentiginousSubstitution - Missense

c.431C>A; p.P144H; 3:147410543-147410543

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.625G>T; p.G209C; 3:147410737-147410737

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.246C>A; p.H82Q; 3:147410358-147410358

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1024C>T; p.R342C; 3:147412559-147412559

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.894C>A; p.G298G; 3:147411006-147411006

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.87C>T; p.A29A; 3:147410199-147410199

 pancreascarcinomaSubstitution - coding silent

c.1024C>T; p.R342C; 3:147412559-147412559

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.87C>T; p.A29A; 3:147410199-147410199

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.983-5A>T; p.?; 3:147412513-147412513

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.833G>A; p.R278H; 3:147410945-147410945

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.410C>A; p.A137D; 3:147410522-147410522

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.833G>A; p.R278H; 3:147410945-147410945

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.978C>A; p.H326Q; 3:147411090-147411090

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.74C>T; p.A25V; 3:147410186-147410186

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.327C>T; p.D109D; 3:147410439-147410439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.486G>T; p.Q162H; 3:147410598-147410598

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.74C>T; p.A25V; 3:147410186-147410186

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.198G>A; p.S66S; 3:147410310-147410310

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.880C>T; p.R294C; 3:147410992-147410992

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.132G>T; p.M44I; 3:147410244-147410244

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.454G>T; p.G152C; 3:147410566-147410566

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1204G>A; p.E402K; 3:147413411-147413411

 skinmalignant_melanomaSubstitution - Missense

c.1116G>A; p.T372T; 3:147412651-147412651

 pancreascarcinomaSubstitution - coding silent

c.1132C>T; p.R378C; 3:147412667-147412667

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1101C>T; p.C367C; 3:147412636-147412636

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.586G>A; p.G196S; 3:147410698-147410698

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.329C>T; p.A110V; 3:147410441-147410441

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1295C>G; p.T432R; 3:147413502-147413502

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.329C>T; p.A110V; 3:147410441-147410441

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.959A>G; p.K320R; 3:147411071-147411071

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.886C>A; p.H296N; 3:147410998-147410998

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.332C>T; p.A111V; 3:147410444-147410444

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.591C>G; p.Y197*; 3:147410703-147410703

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.678C>A; p.I226I; 3:147410790-147410790

 soft_tissue; blood_vesselangiosarcomaSubstitution - coding silent

c.895G>T; p.E299*; 3:147411007-147411007

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Nonsense

c.996C>T; p.F332F; 3:147412531-147412531

 skinmalignant_melanomaSubstitution - coding silent

c.535G>A; p.G179S; 3:147410647-147410647

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.492G>T; p.R164S; 3:147410604-147410604

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.436C>A; p.L146I; 3:147410548-147410548

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.989A>C; p.K330T; 3:147412524-147412524

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.630C>T; p.A210A; 3:147410742-147410742

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1141A>G; p.M381V; 3:147412676-147412676

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.252C>A; p.G84G; 3:147410364-147410364

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1133G>A; p.R378H; 3:147412668-147412668

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1163C>T; p.S388L; 3:147413370-147413370

 skinmalignant_melanomaSubstitution - Missense

c.1163C>T; p.S388L; 3:147413370-147413370

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.108C>T; p.G36G; 3:147410220-147410220

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.165G>C; p.E55D; 3:147410277-147410277

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.951G>C; p.E317D; 3:147411063-147411063

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1030G>A; p.A344T; 3:147412565-147412565

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.466C>T; p.P156S; 3:147410578-147410578

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.396C>A; p.H132Q; 3:147410508-147410508

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.501C>T; p.F167F; 3:147410613-147410613

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.738C>G; p.F246L; 3:147410850-147410850

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.773T>C; p.V258A; 3:147410885-147410885

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1232C>T; p.S411F; 3:147413439-147413439

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1149C>A; p.V383V; 3:147413356-147413356

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1317T>A; p.S439S; 3:147413524-147413524

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1164G>T; p.S388S; 3:147413371-147413371

 livercarcinomaSubstitution - coding silent

c.982+2T>C; p.?; 3:147411096-147411096

 stomachcarcinoma; adenocarcinomaUnknown

c.1143G>T; p.M381I; 3:147412678-147412678

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.444G>A; p.E148E; 3:147410556-147410556

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.831G>A; p.P277P; 3:147410943-147410943

 prostatecarcinomaSubstitution - coding silent

c.72C>T; p.S24S; 3:147410184-147410184

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.864A>G; p.K288K; 3:147410976-147410976

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.325G>A; p.D109N; 3:147410437-147410437

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.307C>T; p.R103C; 3:147410419-147410419

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

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