Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

c.1189C>T; p.P397S; 5:3600137-3600137

c.624C>T; p.S208S; 5:3599572-3599572

c.441C>A; p.N147K; 5:3599389-3599389

c.388C>A; p.R130R; 5:3599336-3599336

c.441C>A; p.N147K; 5:3599389-3599389

c.360C>T; p.Y120Y; 5:3599308-3599308

c.564G>T; p.E188D; 5:3599512-3599512

c.360C>T; p.Y120Y; 5:3599308-3599308

c.1413G>A; p.P471P; 5:3601010-3601010

c.1198G>A; p.A400T; 5:3600146-3600146

c.197C>T; p.A66V; 5:3596302-3596302

c.1413G>A; p.P471P; 5:3601010-3601010

c.1384A>G; p.N462D; 5:3600680-3600680

c.584C>A; p.A195E; 5:3599532-3599532

c.1185C>T; p.G395G; 5:3600133-3600133

c.1185C>T; p.G395G; 5:3600133-3600133

c.1042G>A; p.A348T; 5:3599990-3599990

c.960G>C; p.A320A; 5:3599908-3599908

c.587G>A; p.R196H; 5:3599535-3599535

c.1093A>G; p.T365A; 5:3600041-3600041

c.1267C>G; p.L423V; 5:3600215-3600215

c.396G>A; p.K132K; 5:3599344-3599344

c.1314G>A; p.E438E; 5:3600610-3600610

c.806T>A; p.L269Q; 5:3599754-3599754

c.396G>A; p.K132K; 5:3599344-3599344

c.1062delC; p.A356fs*97; 5:3600010-3600010

c.424C>A; p.L142I; 5:3599372-3599372

c.1171T>A; p.F391I; 5:3600119-3600119

c.370C>A; p.Q124K; 5:3599318-3599318

c.1093A>C; p.T365P; 5:3600041-3600041

c.1093A>C; p.T365P; 5:3600041-3600041

c.744G>A; p.K248K; 5:3599692-3599692

c.531G>T; p.W177C; 5:3599479-3599479

c.385G>A; p.G129R; 5:3599333-3599333

c.462C>T; p.Y154Y; 5:3599410-3599410

c.1386-8C>G; p.?; 5:3600975-3600975

c.1119C>T; p.N373N; 5:3600067-3600067

c.355C>A; p.P119T; 5:3599303-3599303

c.355C>A; p.P119T; 5:3599303-3599303

c.1180G>A; p.V394I; 5:3600128-3600128

c.1357A>C; p.K453Q; 5:3600653-3600653

c.486G>C; p.M162I; 5:3599434-3599434

c.1080C>A; p.S360R; 5:3600028-3600028

c.319G>A; p.A107T; 5:3599267-3599267

c.329C>G; p.A110G; 5:3599277-3599277

c.463C>T; p.P155S; 5:3599411-3599411

c.458C>T; p.P153L; 5:3599406-3599406

c.714C>A; p.G238G; 5:3599662-3599662

c.369C>T; p.F123F; 5:3599317-3599317

c.547C>T; p.R183W; 5:3599495-3599495

c.587G>T; p.R196L; 5:3599535-3599535

c.1286C>T; p.S429L; 5:3600234-3600234

c.553C>T; p.L185F; 5:3599501-3599501

c.690T>C; p.I230I; 5:3599638-3599638

c.558G>T; p.K186N; 5:3599506-3599506

c.696G>C; p.K232N; 5:3599644-3599644

c.884G>A; p.R295H; 5:3599832-3599832

c.491C>A; p.A164D; 5:3599439-3599439

c.661G>A; p.E221K; 5:3599609-3599609

c.361G>A; p.G121S; 5:3599309-3599309

c.328G>T; p.A110S; 5:3599276-3599276

c.282G>C; p.S94S; 5:3599230-3599230

c.1350G>T; p.Q450H; 5:3600646-3600646

c.1379G>A; p.R460H; 5:3600675-3600675

c.413G>T; p.S138I; 5:3599361-3599361

c.447C>A; p.H149Q; 5:3599395-3599395

c.849C>A; p.G283G; 5:3599797-3599797

c.849C>A; p.G283G; 5:3599797-3599797

c.849C>A; p.G283G; 5:3599797-3599797

c.282G>A; p.S94S; 5:3599230-3599230

c.282G>A; p.S94S; 5:3599230-3599230

c.1272T>C; p.N424N; 5:3600220-3600220

c.1287_1288GG>TA; p.V430I; 5:3600235-3600236

c.1412C>G; p.P471R; 5:3601009-3601009

c.1244C>G; p.P415R; 5:3600192-3600192

c.422C>T; p.T141M; 5:3599370-3599370

c.544C>T; p.R182C; 5:3599492-3599492

c.201G>T; p.A67A; 5:3596306-3596306

c.544C>T; p.R182C; 5:3599492-3599492

c.1191C>A; p.P397P; 5:3600139-3600139

c.819C>T; p.D273D; 5:3599767-3599767

c.800C>T; p.S267L; 5:3599748-3599748

c.231C>T; p.S77S; 5:3596336-3596336

c.1045G>T; p.G349W; 5:3599993-3599993

c.817G>A; p.D273N; 5:3599765-3599765

c.1091A>G; p.Y364C; 5:3600039-3600039

c.685G>A; p.D229N; 5:3599633-3599633

c.685G>A; p.D229N; 5:3599633-3599633

c.439A>G; p.N147D; 5:3599387-3599387

c.1383C>G; p.D461E; 5:3600679-3600679

c.541G>A; p.A181T; 5:3599489-3599489

c.1160A>G; p.N387S; 5:3600108-3600108

c.583G>A; p.A195T; 5:3599531-3599531

c.1204C>T; p.H402Y; 5:3600152-3600152

c.342G>A; p.A114A; 5:3599290-3599290

c.341C>T; p.A114V; 5:3599289-3599289

c.507G>T; p.M169I; 5:3599455-3599455

c.1219C>T; p.P407S; 5:3600167-3600167

c.1299C>A; p.S433R; 5:3600247-3600247

c.1133C>G; p.A378G; 5:3600081-3600081

c.1373C>T; p.P458L; 5:3600669-3600669

c.784G>T; p.A262S; 5:3599732-3599732

c.670G>A; p.D224N; 5:3599618-3599618

c.670G>A; p.D224N; 5:3599618-3599618

c.1409C>T; p.T470M; 5:3601006-3601006

c.466A>T; p.T156S; 5:3599414-3599414

c.628A>G; p.T210A; 5:3599576-3599576

c.1273G>T; p.G425*; 5:3600221-3600221

c.611C>T; p.A204V; 5:3599559-3599559

c.611C>T; p.A204V; 5:3599559-3599559

c.611C>T; p.A204V; 5:3599559-3599559

c.406C>A; p.R136S; 5:3599354-3599354

c.747C>T; p.A249A; 5:3599695-3599695

c.747C>T; p.A249A; 5:3599695-3599695

c.535G>A; p.A179T; 5:3599483-3599483

c.535G>A; p.A179T; 5:3599483-3599483

c.1030C>T; p.H344Y; 5:3599978-3599978

c.400G>T; p.A134S; 5:3599348-3599348

c.396G>T; p.K132N; 5:3599344-3599344

c.400G>T; p.A134S; 5:3599348-3599348

c.613C>A; p.L205I; 5:3599561-3599561

c.445_446insTCAACGAGC; p.E148_H149insLNE; 5:3599393-3599394

c.244T>A; p.Y82N; 5:3596349-3596349

c.512T>A; p.L171H; 5:3599460-3599460

c.1385A>G; p.N462S; 5:3600681-3600681

c.658G>A; p.D220N; 5:3599606-3599606

c.561G>A; p.K187K; 5:3599509-3599509

c.514A>G; p.T172A; 5:3599462-3599462

c.620G>T; p.G207V; 5:3599568-3599568

c.601G>A; p.E201K; 5:3599549-3599549

c.1217T>G; p.L406R; 5:3600165-3600165

c.405C>T; p.T135T; 5:3599353-3599353

c.369C>G; p.F123L; 5:3599317-3599317

c.312G>T; p.V104V; 5:3599260-3599260

c.348T>C; p.A116A; 5:3599296-3599296

c.635G>A; p.G212D; 5:3599583-3599583

c.1438G>A; p.A480T; 5:3601035-3601035

c.1438G>A; p.A480T; 5:3601035-3601035

c.1341G>A; p.S447S; 5:3600637-3600637

c.1341G>A; p.S447S; 5:3600637-3600637

c.273G>A; p.Q91Q; 5:3596378-3596378

c.1166G>A; p.R389H; 5:3600114-3600114

c.652G>A; p.E218K; 5:3599600-3599600

c.660C>T; p.D220D; 5:3599608-3599608

c.660C>T; p.D220D; 5:3599608-3599608

c.1166G>A; p.R389H; 5:3600114-3600114

c.475G>A; p.E159K; 5:3599423-3599423

c.1260delG; p.A422fs*31; 5:3600208-3600208

c.212C>T; p.A71V; 5:3596317-3596317

c.1398G>A; p.P466P; 5:3600995-3600995

c.355C>T; p.P119S; 5:3599303-3599303

c.846G>T; p.L282F; 5:3599794-3599794

c.543G>A; p.A181A; 5:3599491-3599491

c.543G>A; p.A181A; 5:3599491-3599491

c.1265C>T; p.A422V; 5:3600213-3600213

c.1419C>T; p.I473I; 5:3601016-3601016

c.619G>T; p.G207C; 5:3599567-3599567

c.1419C>G; p.I473M; 5:3601016-3601016

c.1186G>A; p.A396T; 5:3600134-3600134

c.1186G>A; p.A396T; 5:3600134-3600134

c.526A>G; p.T176A; 5:3599474-3599474

c.348T>G; p.A116A; 5:3599296-3599296

c.709G>A; p.D237N; 5:3599657-3599657

c.1178G>T; p.G393V; 5:3600126-3600126

c.493A>G; p.I165V; 5:3599441-3599441

c.1032C>A; p.H344Q; 5:3599980-3599980

c.1165C>T; p.R389C; 5:3600113-3600113

c.1165C>T; p.R389C; 5:3600113-3600113

c.511C>A; p.L171I; 5:3599459-3599459

c.511C>A; p.L171I; 5:3599459-3599459

c.511C>A; p.L171I; 5:3599459-3599459

c.1187C>A; p.A396D; 5:3600135-3600135

c.1190C>T; p.P397L; 5:3600138-3600138

c.509C>G; p.T170S; 5:3599457-3599457

c.641C>T; p.P214L; 5:3599589-3599589

c.1343C>A; p.P448Q; 5:3600639-3600639

c.378G>A; p.G126G; 5:3599326-3599326

c.329C>T; p.A110V; 5:3599277-3599277

c.1134A>C; p.A378A; 5:3600082-3600082

c.584C>T; p.A195V; 5:3599532-3599532

c.387G>C; p.G129G; 5:3599335-3599335

c.1245G>A; p.P415P; 5:3600193-3600193

c.338C>T; p.T113M; 5:3599286-3599286

c.338C>T; p.T113M; 5:3599286-3599286

c.1439C>G; p.A480G; 5:3601036-3601036

c.928C>T; p.P310S; 5:3599876-3599876

c.765C>T; p.P255P; 5:3599713-3599713

c.1314G>T; p.E438D; 5:3600610-3600610

c.384C>T; p.P128P; 5:3599332-3599332

c.198G>A; p.A66A; 5:3596303-3596303

c.311T>C; p.V104A; 5:3599259-3599259

c.311T>C; p.V104A; 5:3599259-3599259

c.343C>T; p.P115S; 5:3599291-3599291

c.437T>G; p.L146R; 5:3599385-3599385

c.700G>A; p.D234N; 5:3599648-3599648

c.1205A>G; p.H402R; 5:3600153-3600153

c.1205A>G; p.H402R; 5:3600153-3600153

c.872C>A; p.P291Q; 5:3599820-3599820

c.1132G>A; p.A378T; 5:3600080-3600080

c.1132G>A; p.A378T; 5:3600080-3600080

c.665A>T; p.E222V; 5:3599613-3599613

c.735C>T; p.D245D; 5:3599683-3599683

c.811G>A; p.A271T; 5:3599759-3599759

c.339G>A; p.T113T; 5:3599287-3599287

c.1199C>T; p.A400V; 5:3600147-3600147

c.1047G>A; p.G349G; 5:3599995-3599995

c.1142C>A; p.A381E; 5:3600090-3600090

c.630C>T; p.T210T; 5:3599578-3599578

c.472G>A; p.G158S; 5:3599420-3599420

c.820G>A; p.V274I; 5:3599768-3599768

c.548G>A; p.R183Q; 5:3599496-3599496

c.1323C>T; p.L441L; 5:3600619-3600619

c.1361C>T; p.S454L; 5:3600657-3600657

c.1228C>T; p.P410S; 5:3600176-3600176

c.588C>T; p.R196R; 5:3599536-3599536

c.708C>T; p.H236H; 5:3599656-3599656

c.640C>G; p.P214A; 5:3599588-3599588

c.1324G>A; p.V442I; 5:3600620-3600620

c.1324G>A; p.V442I; 5:3600620-3600620

c.447_448CC>AG; p.H149>?; 5:3599395-3599396

c.277-5T>G; p.?; 5:3599220-3599220

c.620G>A; p.G207D; 5:3599568-3599568

c.313C>T; p.H105Y; 5:3599261-3599261

c.1267C>A; p.L423I; 5:3600215-3600215