Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8805

Name

TRIM24

Synonymous

tripartite motif containing 24;TRIM24;tripartite motif containing 24

Definition

E3 ubiquitin-protein ligase TRIM24|RING finger protein 82|TIF1-alpha|transcription intermediary factor 1-alpha|transcriptional intermediary factor 1|tripartite motif-containing 24

Position

7q32-q34

Gene Type

protein-coding

Mutation summary:

Mutations in domains
Mutational pattern in 17 major cancer types
LoF vs missense mutations
All the copy number variations from COSMIC database V72
All the mutations from COSMIC database V72

Mutation summary in protein domains

Top

We used uniprot protein structure data from ensemble BioMart database. The size of circle shows the relative mutation number.

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Top

The non-synonymous mutational pattern in 17 major cancer types.
The synonymous mutational pattern in 17 major cancer types.

Loss of Function mutations compare to missense mutations

Top

Loss of Function mutations compare to missense mutation.
The ratio of the loss-of-function mutations over missense mutations is 0.13.

The copy number variations for various cancers

Top

The copy number variations in 17 major cancer groups: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

COSMIC somatic mutation [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.508G>A; p.A170T; 7:138515236-138515236

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.833T>A; p.M278K; 7:138525309-138525309

 ovaryother; neoplasmSubstitution - Missense

c.833T>A; p.M278K; 7:138525309-138525309

 ovaryother; neoplasmSubstitution - Missense

c.2299A>G; p.S767G; 7:138579246-138579246

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2390C>T; p.S797F; 7:138579337-138579337

 skinmalignant_melanomaSubstitution - Missense

c.150C>G; p.L50L; 7:138460698-138460698

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.2502C>T; p.N834N; 7:138579449-138579449

 prostateadenomaSubstitution - coding silent

c.1535C>T; p.P512L; 7:138567485-138567485

 skinmalignant_melanomaSubstitution - Missense

c.1535C>T; p.P512L; 7:138567485-138567485

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2670A>G; p.E890E; 7:138580646-138580646

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.2531G>A; p.C844Y; 7:138579478-138579478

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1315C>T; p.P439S; 7:138554751-138554751

 skinmalignant_melanomaSubstitution - Missense

c.1315C>T; p.P439S; 7:138554751-138554751

 skin; neckmalignant_melanomaSubstitution - Missense

c.1287G>T; p.E429D; 7:138554723-138554723

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2610C>T; p.C870C; 7:138580586-138580586

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.3127A>G; p.I1043V; 7:138584925-138584925

 breastcarcinomaSubstitution - Missense

c.2589A>G; p.G863G; 7:138580565-138580565

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.655C>T; p.R219*; 7:138519212-138519212

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.706G>A; p.E236K; 7:138519263-138519263

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.652C>T; p.Q218*; 7:138519209-138519209

 breastcarcinomaSubstitution - Nonsense

c.819A>G; p.L273L; 7:138525295-138525295

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2382G>A; p.Q794Q; 7:138579329-138579329

 skinmalignant_melanomaSubstitution - coding silent

c.835_836insA; p.T281fs*17; 7:138525311-138525312

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.475T>A; p.S159T; 7:138504400-138504400

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2320G>C; p.E774Q; 7:138579267-138579267

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2037A>C; p.V679V; 7:138576395-138576395

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.141G>A; p.A47A; 7:138460689-138460689

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.2728C>T; p.R910C; 7:138581706-138581706

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2728C>T; p.R910C; 7:138581706-138581706

 pancreascarcinomaSubstitution - Missense

c.2728C>T; p.R910C; 7:138581706-138581706

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_relatedSubstitution - Missense

c.1265C>A; p.S422Y; 7:138554701-138554701

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2728C>T; p.R910C; 7:138581706-138581706

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.574C>T; p.Q192*; 7:138515302-138515302

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1378C>T; p.P460S; 7:138554814-138554814

 skinmalignant_melanomaSubstitution - Missense

c.1378C>T; p.P460S; 7:138554814-138554814

 skinmalignant_melanomaSubstitution - Missense

c.2906T>G; p.F969C; 7:138583962-138583962

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.390C>T; p.C130C; 7:138504315-138504315

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2906T>G; p.F969C; 7:138583962-138583962

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1661A>C; p.N554T; 7:138567611-138567611

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1568G>A; p.S523N; 7:138567518-138567518

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2110G>A; p.A704T; 7:138577442-138577442

 livercarcinomaSubstitution - Missense

c.2835G>C; p.L945F; 7:138583891-138583891

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2110G>A; p.A704T; 7:138577442-138577442

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.2530T>C; p.C844R; 7:138579477-138579477

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1248T>A; p.N416K; 7:138551167-138551167

 skin; acralmalignant_melanomaSubstitution - Missense

c.794A>T; p.N265I; 7:138525270-138525270

 breastcarcinomaSubstitution - Missense

c.831G>A; p.L277L; 7:138525307-138525307

 breastcarcinomaSubstitution - coding silent

c.3019_3020insA; p.R1009fs*10; 7:138584817-138584818

 large_intestine; rectumcarcinoma; adenocarcinomaInsertion - Frameshift

c.2653C>T; p.P885S; 7:138580629-138580629

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1676C>T; p.A559V; 7:138567626-138567626

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.3006G>C; p.K1002N; 7:138584804-138584804

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2871C>A; p.S957S; 7:138583927-138583927

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1152C>T; p.Y384Y; 7:138551071-138551071

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.438G>A; p.K146K; 7:138504363-138504363

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.117G>A; p.P39P; 7:138460665-138460665

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.2560G>C; p.V854L; 7:138579507-138579507

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.676C>G; p.H226D; 7:138519233-138519233

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2285C>T; p.S762F; 7:138579232-138579232

 skinmalignant_melanomaSubstitution - Missense

c.619G>A; p.E207K; 7:138515347-138515347

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1718G>T; p.S573I; 7:138570843-138570843

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1455A>G; p.Q485Q; 7:138554891-138554891

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2596A>C; p.I866L; 7:138580572-138580572

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2078G>T; p.S693I; 7:138576436-138576436

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1251C>T; p.I417I; 7:138551170-138551170

 skinmalignant_melanomaSubstitution - coding silent

c.2126C>T; p.T709I; 7:138577458-138577458

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1275C>T; p.I425I; 7:138554711-138554711

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1377C>T; p.F459F; 7:138554813-138554813

 skinmalignant_melanomaSubstitution - coding silent

c.1489A>G; p.R497G; 7:138554925-138554925

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1989A>G; p.S663S; 7:138573617-138573617

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2504G>A; p.G835E; 7:138579451-138579451

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.3027G>T; p.R1009S; 7:138584825-138584825

 central_nervous_system; medullaprimitive_neuroectodermal_tumour-medulloblastoma; classicSubstitution - Missense

c.2683G>A; p.E895K; 7:138580659-138580659

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2995G>A; p.E999K; 7:138584793-138584793

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.3137G>A; p.R1046H; 7:138584935-138584935

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2869T>C; p.S957P; 7:138583925-138583925

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1207A>G; p.T403A; 7:138551126-138551126

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1191C>T; p.S397S; 7:138551110-138551110

 skinmalignant_melanomaSubstitution - coding silent

c.1500G>A; p.G500G; 7:138554936-138554936

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.3001C>G; p.L1001V; 7:138584799-138584799

 breastcarcinomaSubstitution - Missense

c.1349G>T; p.G450V; 7:138554785-138554785

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.376C>T; p.R126C; 7:138504301-138504301

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.376C>T; p.R126C; 7:138504301-138504301

 skinmalignant_melanomaSubstitution - Missense

c.2000C>T; p.S667F; 7:138573628-138573628

 thyroidcarcinomaSubstitution - Missense

c.3104C>T; p.P1035L; 7:138584902-138584902

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.3029T>G; p.F1010C; 7:138584827-138584827

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2155C>T; p.P719S; 7:138577487-138577487

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1334C>T; p.S445L; 7:138554770-138554770

 skinmalignant_melanomaSubstitution - Missense

c.1690C>A; p.Q564K; 7:138567640-138567640

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.623T>C; p.V208A; 7:138515351-138515351

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1461G>C; p.R487S; 7:138554897-138554897

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.2083G>A; p.G695R; 7:138576441-138576441

 skinmalignant_melanomaSubstitution - Missense

c.1874C>T; p.P625L; 7:138570999-138570999

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1874C>T; p.P625L; 7:138570999-138570999

 skinmalignant_melanomaSubstitution - Missense

c.3105C>T; p.P1035P; 7:138584903-138584903

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.2087G>A; p.S696N; 7:138576445-138576445

 oesophaguscarcinomaSubstitution - Missense

c.2312C>T; p.S771F; 7:138579259-138579259

 skinmalignant_melanomaSubstitution - Missense

c.1015C>T; p.R339C; 7:138538675-138538675

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1015C>T; p.R339C; 7:138538675-138538675

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.732A>T; p.R244R; 7:138519289-138519289

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.2312C>G; p.S771C; 7:138579259-138579259

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2049A>G; p.I683M; 7:138576407-138576407

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1912_1913insT; p.V639fs*6; 7:138573540-138573541

 livercarcinoma; hepatocellular_carcinomaInsertion - Frameshift

c.2607C>G; p.F869L; 7:138580583-138580583

 breastcarcinomaSubstitution - Missense

c.2858_2860delAAG; p.E954delE; 7:138583914-138583916

 pancreascarcinoma; acinar_carcinomaDeletion - In frame

c.26T>G; p.V9G; 7:138460574-138460574

 thyroidother; neoplasmSubstitution - Missense

c.433G>T; p.V145L; 7:138504358-138504358

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2227G>A; p.E743K; 7:138577559-138577559

 skinmalignant_melanomaSubstitution - Missense

c.3005A>G; p.K1002R; 7:138584803-138584803

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.3141G>C; p.Q1047H; 7:138584939-138584939

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.3005A>G; p.K1002R; 7:138584803-138584803

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.436A>C; p.K146Q; 7:138504361-138504361

 skinmalignant_melanomaSubstitution - Missense

c.1597C>T; p.P533S; 7:138567547-138567547

 stomachcarcinomaSubstitution - Missense

c.2161C>T; p.R721*; 7:138577493-138577493

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2161C>T; p.R721*; 7:138577493-138577493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2161C>T; p.R721*; 7:138577493-138577493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2161C>T; p.R721*; 7:138577493-138577493

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2161C>T; p.R721*; 7:138577493-138577493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2161C>T; p.R721*; 7:138577493-138577493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.2050C>T; p.R684C; 7:138576408-138576408

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2119G>C; p.D707H; 7:138577451-138577451

 ovaryother; neoplasmSubstitution - Missense

c.404C>G; p.A135G; 7:138504329-138504329

 breastcarcinomaSubstitution - Missense

c.2717G>A; p.R906K; 7:138580693-138580693

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.532G>C; p.E178Q; 7:138515260-138515260

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2717G>A; p.R906K; 7:138580693-138580693

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1596T>A; p.P532P; 7:138567546-138567546

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1509G>C; p.Q503H; 7:138554945-138554945

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2754T>A; p.H918Q; 7:138581732-138581732

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2719-1G>C; p.?; 7:138581696-138581696

 lungcarcinoma; adenocarcinomaUnknown

c.594A>G; p.K198K; 7:138515322-138515322

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.3067A>C; p.K1023Q; 7:138584865-138584865

 kidneyother; neoplasmSubstitution - Missense

c.3067A>C; p.K1023Q; 7:138584865-138584865

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1339C>T; p.P447S; 7:138554775-138554775

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1426C>T; p.Q476*; 7:138554862-138554862

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1296A>G; p.P432P; 7:138554732-138554732

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2932G>A; p.E978K; 7:138583988-138583988

 central_nervous_system; braingliomaSubstitution - Missense

c.1492A>C; p.M498L; 7:138554928-138554928

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2581C>G; p.P861A; 7:138579528-138579528

 livercarcinomaSubstitution - Missense

c.2581C>G; p.P861A; 7:138579528-138579528

 livercarcinomaSubstitution - Missense

c.641G>T; p.G214V; 7:138519198-138519198

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1995G>A; p.V665V; 7:138573623-138573623

 livercarcinomaSubstitution - coding silent

c.1171C>T; p.R391C; 7:138551090-138551090

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1754C>T; p.S585F; 7:138570879-138570879

 skinmalignant_melanomaSubstitution - Missense

c.1995G>A; p.V665V; 7:138573623-138573623

 livercarcinomaSubstitution - coding silent

c.1171C>T; p.R391C; 7:138551090-138551090

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1729A>G; p.T577A; 7:138570854-138570854

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1729A>G; p.T577A; 7:138570854-138570854

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1729A>G; p.T577A; 7:138570854-138570854

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1729A>G; p.T577A; 7:138570854-138570854

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1844T>A; p.V615E; 7:138570969-138570969

 kidneyother; neoplasmSubstitution - Missense

c.3106C>T; p.R1036W; 7:138584904-138584904

 skinmalignant_melanomaSubstitution - Missense

c.258G>A; p.Q86Q; 7:138460806-138460806

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1598C>A; p.P533H; 7:138567548-138567548

 breastcarcinomaSubstitution - Missense

c.2676G>A; p.K892K; 7:138580652-138580652

 skin; upper_armmalignant_melanomaSubstitution - coding silent

c.1583G>A; p.G528E; 7:138567533-138567533

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2252delA; p.N752fs*14; 7:138577584-138577584

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.2252delA; p.N752fs*14; 7:138577584-138577584

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.2651C>A; p.A884D; 7:138580627-138580627

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2531_2532insC; p.K846fs*30; 7:138579478-138579479

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1481C>G; p.P494R; 7:138554917-138554917

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.903T>C; p.N301N; 7:138529137-138529137

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.1207A>C; p.T403P; 7:138551126-138551126

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.2587G>T; p.G863*; 7:138580563-138580563

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.1413G>C; p.Q471H; 7:138554849-138554849

 pancreascarcinomaSubstitution - Missense

c.1173T>C; p.R391R; 7:138551092-138551092

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1173T>C; p.R391R; 7:138551092-138551092

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1016G>A; p.R339H; 7:138538676-138538676

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1775C>T; p.T592M; 7:138570900-138570900

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1703A>G; p.Q568R; 7:138567653-138567653

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.2669delA; p.K892fs*9; 7:138580645-138580645

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.329C>T; p.S110L; 7:138460877-138460877

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.329C>T; p.S110L; 7:138460877-138460877

 livercarcinomaSubstitution - Missense

c.1879-2A>T; p.?; 7:138573505-138573505

 livercarcinomaUnknown

c.2314A>G; p.T772A; 7:138579261-138579261

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1879-2A>T; p.?; 7:138573505-138573505

 livercarcinomaUnknown

c.808A>G; p.I270V; 7:138525284-138525284

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1172G>A; p.R391H; 7:138551091-138551091

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.2040delC; p.P682fs*41; 7:138576398-138576398

 NSmalignant_melanomaDeletion - Frameshift

c.1172G>A; p.R391H; 7:138551091-138551091

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.2871C>T; p.S957S; 7:138583927-138583927

 skinmalignant_melanomaSubstitution - coding silent

c.769C>T; p.Q257*; 7:138525245-138525245

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.194G>A; p.S65N; 7:138460742-138460742

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1406G>A; p.R469Q; 7:138554842-138554842

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2871C>T; p.S957S; 7:138583927-138583927

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2871C>T; p.S957S; 7:138583927-138583927

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2871C>T; p.S957S; 7:138583927-138583927

 breastcarcinoma; ductal_carcinomaSubstitution - coding silent

c.2571G>C; p.L857F; 7:138579518-138579518

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

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