| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10010 |
Name | TANK |
Synonymous | I-TRAF|ITRAF|TRAF2;TRAF family member-associated NFKB activator;TANK;TRAF family member-associated NFKB activator |
Definition | TRAF family member-associated NF-kappa-B activator|TRAF-interacting protein |
Position | 2q24.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for TANK | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
TANK(h) + IKK-gamma(m) <==> TANK(h):IKK-gamma(m) (binding) | TANK(h) + IKK-gamma(h) + IKK-beta(h) <==> TANK(h):IKK-gamma(h):IKK-beta(h) (binding) | IKK-i(h) + TANK(h) + IKK-gamma(h) <==> IKK-i(h):TANK(h):IKK-gamma(h) (binding) | TBK1(h) + TANK(h) + IKK-gamma(h) <==> TBK1(h):TANK(h):IKK-gamma(h) (binding) | IKK-i(h) + TANK(h) + IKK-alpha(h) <==> IKK-i(h):TANK(h):IKK-alpha(h) (binding) | IKK-i(h) + TANK(h) <==> IKK-i(h):TANK(h) (binding) | TANK(h) + IKK-alpha(h) <==> TANK(h):IKK-alpha(h) (binding) | TANK(h) + ATP --> TANK(h){p} + ADP (phosphorylation) | TANK(h) --> IL8(h) (transactivation) | TANK(h) + TBK1(h) <==> TANK(h):TBK1(h) (binding) | IKK-i(h) + TANK(h) <==> IKK-i(h):TANK(h) (binding) | TANK(h) + Zinc finger CCCH domain-containing protein 12A(h) <==> TANK(h):Zinc finger CCCH domain-containing protein 12A(h) (binding) | IRF-7(h) + TANK(h) <==> IRF-7(h):TANK(h) (binding) | IRF-3(m.s.) + TANK(h) <==> IRF-3(m.s.):TANK(h) (binding) | IRF-7(m.s.) + TANK(h) <==> IRF-7(m.s.):TANK(h) (binding) | TANK(h) + IKK-i(m.s.) <==> IKK-i(m.s.):TANK(h) (binding) | TBK1(m.s.) + TANK(h) <==> TBK1(m.s.):TANK(h) (binding) | TRAF3(h) + TANK(h) + TBK1(m.s.) <==> TRAF3(h):TANK(h):TBK1(m.s.) (binding) | TANK(h) + ATP --IKK-i(m.s.)--> TANK(h){p} + ADP (phosphorylation) | TANK(h) + ATP --TBK1(m.s.)--> TANK(h){p} + ADP (phosphorylation) | TANK(h) + ATP --TBK1(h)--> TANK(h){p} + ADP (phosphorylation) | TANK(h) + n ubiquitin(h) --> TANK(h){ubK}n (ubiquitination) | TANK(h) + TRAF3(h) <==> TANK(h):TRAF3(h) (binding) | TANK(h) + n ubiquitin(m.s.) --> TANK(h){ub{K63}(n)} (ubiquitination) | TANK(h) + n ubiquitin(h) --> TANK(h){ub{K63}(n)} (ubiquitination) | TANK(h) + n ubiquitin(h) --Ubc13(h)--> TANK(h){ub{K63}(n)} (ubiquitination) | TANK(h) --> TANK(h) (expression). | IKK-gamma(m) + TANK(h) <==> IKK-gamma(m):TANK(h) (binding) | 2 TANK(h) <==> (TANK(h))2 (oligomerization) | TANK(h) + ATP --> TANK(h){p} + ADP (phosphorylation) | TANK(h) + ATP --IKK-beta(m)--> TANK(h){p} + ADP (phosphorylation) | TANK(h) + IKK-i(h) <==> TANK(h):IKK-i(h) (binding) | TANK(h) + TBK1(h) <==> TANK(h):TBK1(h) (binding) | IKK-i(h) + TANK(h) <==> IKK-i(h):TANK(h) (binding) | TANK(h) + ATP --IKK-i(h)--> TANK(h){p} + ADP (phosphorylation) | TRAF2(m.s.) + TANK(h) <==> TRAF2(m.s.):TANK(h) (binding) | TANK(h) --> TANK(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
225 | Phosphoserine. | Swiss-Prot 53.0 | 228 | Phosphoserine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for TANK | ||