General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 1030 |
Name | CDKN2B |
Synonymous | CDK4I|INK4B|MTS2|P15|TP15|p15INK4b;cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4);CDKN2B;cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
Definition | CDK inhibitory protein|CDK4B inhibitor|MTS-2|cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinases 4 and 6 binding protein|multiple tumor suppressor 2|p14-INK4b|p14_CDK inhibitor|p14_INK4B|p15 CDK inhibitor|p15-INK4b|p15_INK4B |
Position | 9p21 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
Cdk6(h) + p15INK4b(h) <==> Cdk6(h):p15INK4b(h) (binding) | Cdk4(h) + p15INK4b(h) <==> Cdk4(h):p15INK4b(h) (binding) | p15INK4b(h) + MAGE11(h) <==> p15INK4b(h):MAGE11(h) (binding) | CDKN2B(h) --> p15INK4b(h) (expression). | TGFbeta1(h) --> p15INK4b(h) (increase of abundance) | TGFbeta1(m.s.) --> p15INK4b(h) (increase of abundance) | TGFbeta2(m.s.) --> p15INK4b(h) (increase of abundance) | p15INK4b(h) + Cdk4(h) <==> p15INK4b(h):Cdk4(h) (binding) | p15INK4b(h) + Cdk6(h) <==> p15INK4b(h):Cdk6(h) (binding) | p15INK4b(h) --/ p21Cip1(h) (decrease of abundance) | CDKN2B(h) --> p15INK4b(h) (expression). | Smad4(m.s.) --> p15INK4b(h) (increase of abundance) |
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Post Transcriptional Modification [Top] | |||
There is no record for CDKN2B |
Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
---|---|---|
chr9 |
Promoter: 21998812 - 22000812 | Agilent_014791 |
chr9 |
Promoter: 21998812 - 22000812 | GoldenGate_Methylation_Cancer_Panel_I |
chr9 |
Promoter: 21998812 - 22000812 | GoldenGate_Methylation_Cancer_Panel_I |
chr9 |
Promoter: 21998812 - 22000812 | GSE27584 |
chr9 |
Promoter: 21998812 - 22000812 | GSE27584 |
chr9 |
Promoter: 21998812 - 22000812 | Agilent_014791_44K |
chr9 |
Promoter: 21998812 - 22000812 | E-GEOD-20553 |
chr9 |
Promoter: 21998812 - 22000812 | E-GEOD-20553 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:20064646 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:20064646 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11413509 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11413509 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14513284 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14513284 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15495254 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15495254 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12970781 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12970781 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10706859 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10706859 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10634644 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10634644 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11532526 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11532526 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15863205 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15863205 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11877040 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11877040 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11283136 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11283136 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12899712 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12899712 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15198948 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15198948 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16192589 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16192589 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9399648 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9399648 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15475071 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15475071 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16682076 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16682076 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10764143 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10764143 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11167795 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11167795 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15755284 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15755284 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9269757 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9269757 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11584062 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11584062 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16343268 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16343268 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12114423 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12114423 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12548613 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12548613 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16565223 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16565223 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11721363 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11721363 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12150726 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12150726 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17056112 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17056112 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12750706 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12750706 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10779450 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10779450 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9473234 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9473234 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10477703 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10477703 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12213729 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12213729 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16406514 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16406514 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12060387 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12060387 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15897551 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15897551 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11786399 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11786399 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9639423 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:9639423 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16858686 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16858686 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12447702 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12447702 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15892004 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15892004 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11764089 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11764089 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11487055 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11487055 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14581362 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14581362 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14636164 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14636164 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17216555 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17216555 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15112341 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15112341 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12937151 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12937151 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16764763 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16764763 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10999738 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10999738 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12143052 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12143052 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17289889 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17289889 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15467712 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15467712 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15197802 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15197802 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15109538 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15109538 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12578664 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12578664 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12906163 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12906163 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11243384 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11243384 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15260845 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15260845 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11445839 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11445839 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11895880 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11895880 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15189501 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15189501 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15526363 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15526363 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16872319 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16872319 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15389252 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15389252 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14719065 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:14719065 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12448005 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12448005 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11413518 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11413518 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12060614 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12060614 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17369979 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17369979 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12767073 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12767073 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15073117 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15073117 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12632081 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12632081 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17177027 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:17177027 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16000597 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16000597 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12376481 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12376481 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10537333 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:10537333 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12374684 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12374684 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12672028 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12672028 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12932666 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:12932666 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15221997 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15221997 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15154012 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15154012 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11839665 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:11839665 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15713962 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15713962 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15892297 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15892297 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16537562 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:16537562 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15447999 |
chr9 |
Promoter: 21998812 - 22000812 | PMID:15447999 |