| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10399 |
Name | GNB2L1 |
Synonymous | Gnb2-rs1|H12.3|HLC-7|PIG21|RACK1;guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1;GNB2L1;guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
Definition | cell proliferation-inducing gene 21 protein|guanine nucleotide binding protein beta polypeptide 2-like 1|guanine nucleotide-binding protein subunit beta-2-like 1|guanine nucleotide-binding protein subunit beta-like protein 12.3|human lung cancer oncogene |
Position | 5q35.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
RACK1(h) + STAT1(h) <==> RACK1(h):STAT1(h) (binding) | IFNAR2(h) + RACK1(h) <==> IFNAR2(h):RACK1(h) (binding) | beta2-integrin(h) + RACK1(h) <==> beta2-integrin(h):RACK1(h) (binding) | beta1-integrin(h) + RACK1(h) <==> beta1-integrin(h):RACK1(h) (binding) | alphaL-integrin(h):beta2-integrin(h) + RACK1(h) <==> alphaL-integrin(h):beta2-integrin(h):RACK1(h) (binding) | RACK1(h) + p73alpha(v.s.) <==> RACK1(h):p73alpha(v.s.) (binding) | RACK1(h) + pRb(h) <==> RACK1(h):pRb(h) (binding) | PDE4D5(h) + RACK1(h) <==> PDE4D5(h):RACK1(h) (binding) | RACK1(h) + IL-5Rbeta(m.s.) <==> RACK1(h):IL-5Rbeta(m.s.) (binding) | RACK1(h) + PLCgamma1(b) <==> RACK1(h):PLCgamma1(b) (binding) | RACK1(h) + RasGAP(m.s.) <==> RACK1(h):RasGAP(m.s.) (binding) | RACK1(h) + Src(m) <==> RACK1(h):Src(m) (binding) | RACK1(h) + ATRAP-isoform1(h) <==> RACK1(h):ATRAP-isoform1(h) (binding) | RACK1(h) + Tilz2(h) <==> RACK1(h):Tilz2(h) (binding) | RACK1(h) + PTN(h) <==> RACK1(h):PTN(h) (binding) | GOLPH2(h) + RACK1(h) <==> GOLPH2(h):RACK1(h) (binding) | FATP-6(h) + RACK1(h) <==> FATP-6(h):RACK1(h) (binding) | Jak1(h) + SHP-2(h) + PKCbeta(h) + RACK1(h) <==> RACK1(h):SHP-2(h):Jak1(h):PKCbeta(h) (binding) | AdipoR1(h) + RACK1(h) <==> AdipoR1(h):RACK1(h) (binding) | GNB2L1(h) --> RACK1(h) (expression). | RACK1(h) + PDE4D5(h) <==> RACK1(h):PDE4D5(h) (binding) | RACK1(h) + GR-alpha(h) <==> RACK1(h):GR-alpha(h) (binding) | IL-5Rbeta-isoform1(h) + RACK1(h) <==> IL-5Rbeta-isoform1(h):RACK1(h) (binding) | RACK1(h) + Src-isoform-1(c) <==> RACK1(h):Src-isoform-1(c) (binding) | RACK1(h) + ATP --Src-isoform-1(c)--> RACK1(h){pY} + ADP (phosphorylation) | RACK1(h) + ATP --> RACK1(h){pY} + ADP (phosphorylation) | TRPM6(m.s.) + RACK1(h) <==> TRPM6(m.s.):RACK1(h) (binding) | AdipoR1(h) + RACK1(h) <==> AdipoR1(h):RACK1(h) (binding) | GNB2L1(h) --> RACK1(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylthreonine. | Swiss-Prot 53.0 | 228 | Phosphotyrosine. | Swiss-Prot 53.0 | 227 | Phosphotyrosine (Src) | 12400005 | Phospho.ELM 6.0 | 245 | Phosphotyrosine (Src) | 12400005 | Phospho.ELM 6.0 | 193 | Phosphotyrosine (Tyk2) | 15240704 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 180603012 - 180605012 | Agilent_014791 |
chr5 |
Promoter: 180603012 - 180605012 | GSE27584 |