General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 10413 |
Name | YAP1 |
Synonymous | COB1|YAP|YAP2|YAP65|YKI;Yes-associated protein 1;YAP1;Yes-associated protein 1 |
Definition | 65 kDa Yes-associated protein|protein yorkie homolog|transcriptional coactivator YAP1|yes-associated protein 2|yes-associated protein YAP65 homolog|yorkie homolog |
Position | 11q13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
p73alpha(mo) + YAP(h) <==> p73alpha(mo):YAP(h) (binding) | p73beta(m) + YAP(h) <==> p73beta(m):YAP(h) (binding) | p63alpha(m) + YAP(h) <==> p63alpha(m):YAP(h) (binding) | Smad7(m) + YAP(h) <==> Smad7(m):YAP(h) (binding) | YAP(h) + ATP --> YAP(h){pS127} + ADP (phosphorylation) | YAP1(h) --> YAP(h) (expression). | YAP(h) + SAF-A(h) <==> YAP(h):SAF-A(h) (binding) | YAP(h) + 14-3-3(h) <==> YAP(h):14-3-3(h) (binding) | YAP(h) --> YAP(h) (translocation) | ErbB4(m.s.) + YAP(h) <==> ErbB4(m.s.):YAP(h) (binding) | YAP(h) + ErbB4-CTF(h) <==> YAP(h):ErbB4-CTF(h) (binding) | YAP1(h) --> YAP(h) (expression). | YAP(h) --> YAP(h) (translocation) |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
109 | Phosphoserine. | Swiss-Prot 53.0 | 110 | Phosphothreonine. | Swiss-Prot 53.0 | 127 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 128 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 143 | Phosphothreonine. | Swiss-Prot 53.0 | 154 | Phosphothreonine. | Swiss-Prot 53.0 | 238 | Phosphoserine. | Swiss-Prot 53.0 | 347 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 348 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 109 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 138 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr11 |
Promoter: 101485041 - 101487041 | Agilent_014791 |
chr11 |
Promoter: 101485041 - 101487041 | GSE27584 |
chr11 |
Promoter: 101485041 - 101487041 | Agilent_014791_44K |