Entrez Gene

Basic Information
Gene ID	1045
Name	CDX2
Synonymous	CDX-3\|CDX2/AS\|CDX3;caudal type homeobox 2;CDX2;caudal type homeobox 2
Definition	caudal type homeo box transcription factor 2\|caudal type homeobox transcription factor 2\|caudal-type homeobox protein 2\|homeobox protein CDX-2
Position	13q12.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Cdx-2(h) --> Lct(pg) (DNA binding).
Cdx-2(h) --> GUCY2C(h) (DNA binding).
Cdx-2(h) --> BCL2(h) (DNA binding).
Cdx-2(h) --> MUC2(h) (DNA binding; transactivation).
Cdx-2(h) --> Glc6Pase(r) (DNA binding).
Cdx-2(h) --> CLDN2(h) (DNA binding).
Cdx-2(h) --> RAGE(h) (DNA binding; transactivation).
Cdx-2(h) --> SI(h) (DNA binding).
Cdx-2(h) --> NOX1(h) (DNA binding).
Cdx-2(h) --> MUC4(h) (DNA binding).
Cdx-2(h) --> ACAT2(h) (DNA binding).
CDX2(h) --> Cdx-2(h) (expression).
beta-catenin(h) --> Cdx-2(h) (increase of abundance)
Cdx-2(h) --> UGT1A8(h) (DNA binding; transactivation).
Cdx-2(h) --> UGT1A10(h) (DNA binding; transactivation).
Cdx-2(h) --> Fabp1(r) (transactivation)
HNF-1alpha(m) + Cdx-2(h) <==> HNF-1alpha(m):Cdx-2(h) (binding)
HNF-1beta(m) + Cdx-2(h) <==> HNF-1beta(m):Cdx-2(h) (binding)
Cdx-2(h) --> SI(h) (DNA binding).
Cdx-2(h) --> NOX1(h) (DNA binding).
Cdx-2(h) --> p21Cip1(h) (increase of abundance)
Cdx-2(h) --> CDKN1A(h) (transactivation)
Cdx-2(h) --/ p16INK4a(h) (decrease of abundance)
Cdx-2(h) --/ p27Kip1(h) (decrease of abundance)
Cdx-2(h) --/ cyclinD1(h) (decrease of abundance)
Cdx-2(h) --/ cyclinA(h) (decrease of abundance)
Cdx-2(h) --/ pRb(h) (decrease of abundance)
Cdx-2(h) --/ pRb(h){p} (decrease of abundance)
Cdx-2(h) --> B3GALT5(h) (transactivation)
Cdx-2(h) --> MUC2(h) (transactivation)
CDX2(h) --> Cdx-2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
60	Phosphoserine (By similarity).		Swiss-Prot 53.0