| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10524 |
Name | KAT5 |
Synonymous | ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2;K(lysine) acetyltransferase 5;KAT5;K(lysine) acetyltransferase 5 |
Definition | 60 kDa Tat-interactive protein|HIV-1 Tat interactive protein, 60kDa|K-acetyltransferase 5|Tat interacting protein, 60kDa|cPLA(2)-interacting protein|cPLA2 interacting protein|histone acetyltransferase HTATIP|histone acetyltransferase KAT5 |
Position | 11q13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
APP(h) + Fe65(r) + Tip60(h) <==> APP(h):Fe65(r):Tip60(h) (binding; transactivation) | AICD59(h) + Tip60(h) <==> AICD59(h):Tip60(h) (binding) | Tip60(h) + ATP --> Tip60(h){pS86}{pS90} + ADP (phosphorylation) | Tip60(h) + ATP --Cdk2(h)--> Tip60(h){pS90} + ADP (phosphorylation) | EP400(h) + BAF53a(h) + Pontin52(h) + Reptin52(h) + TRCp120(h) + MRGX(h) + MRG15(h) + DMAP1(h) + MRGBP(h) + trrap(h) + Tip60(h) <==> BAF53a(h):DMAP1(h):EP400(h):MRG15(h):MRGBP(h):MRGX(h):Pontin52(h):Reptin52(h):Tip60(h):TRCp120(h):trrap(h) (binding) | HDAC7(m) + Tip60(h) <==> HDAC7(m):Tip60(h) (binding) | STAT3(m) + Tip60(h) <==> STAT3(m):Tip60(h) (binding) | mdm2(h) + Tip60(h) <==> mdm2(h):Tip60(h) (binding) | mdm2(m) + Tip60(h) <==> mdm2(m):Tip60(h) (binding) | n ubiquitin(h) + Tip60(h) --mdm2(m)--> Tip60(h){ub(n)} (ubiquitination) | PIRH2(h) + Tip60(h) <==> PIRH2(h):Tip60(h) (binding) | CD91-ICD(h) + Tip60(h) <==> CD91-ICD(h):Tip60(h) (binding) | Fe65(h) + Tip60(h) + AICD59(h) <==> AICD59(h):Fe65(h):Tip60(h) (binding) | Tip60(h) + Bcl-3(h) + beta-catenin(h) + Reptin52(h) <==> Bcl-3(h):beta-catenin(h):Reptin52(h):Tip60(h) (binding) | Tip60(h) + Pontin52(h) + Bcl-3(h) <==> Bcl-3(h):Pontin52(h):Tip60(h) (binding) | Pontin52(h) + Tip60(h) + NF-kappaB1-p50(h):NF-kappaB1-p50(h) + Bcl-3(h) <==> Pontin52(h):Tip60(h):NF-kappaB1-p50(h):NF-kappaB1-p50(h):Bcl-3(h) (binding) | BARD1(h) + Tip60(h) <==> BARD1(h):Tip60(h) (binding) | GADD45-gamma(h) + Tip60(h) <==> GADD45-gamma(h):Tip60(h) (binding) | Tip60(h) + GAPD(h) <==> Tip60(h):GAPD(h) (binding) | Tip60(h) + GCN5(h) + Pontin52(h) + BAF53a(h) + trrap(h) <==> Tip60(h):GCN5(h):Pontin52(h):BAF53a(h):trrap(h) (binding) | Tip60(h) + c-Myc(h) <==> Tip60(h):c-Myc(h) (binding) | Tip60(h) + HDAC1(h) + AR(h) <==> Tip60(h):HDAC1(h):AR(h) (binding) | ER-alpha(h) + Tip60(h) <==> ER-alpha(h):Tip60(h) (binding) | p16INK4a(h) + Tip60(h) <==> p16INK4a(h):Tip60(h) (binding) | Bcl-3(h) + Tip60(h) <==> Bcl-3(h):Tip60(h) (binding) | pdcd5(h) + Tip60(h) <==> pdcd5(h):Tip60(h) (binding) | Tip60(h) --> pdcd5(h) (increase of abundance) | 2H9(h) + Tip60(h) <==> 2H9(h):Tip60(h) (binding) | SSAT(h) + Tip60(h) <==> SSAT(h):Tip60(h) (binding) | ZNF-24(h) + Tip60(h) <==> ZNF-24(h):Tip60(h) (binding) | TRB3(h) + Tip60(h) <==> TRB3(h):Tip60(h) (binding) | PCGF4(h) + Tip60(h) <==> PCGF4(h):Tip60(h) (binding) | CstF-64(h) + Tip60(h) <==> CstF-64(h):Tip60(h) (binding) | IK(h) + Tip60(h) <==> IK(h):Tip60(h) (binding) | lamin-A(h) + Tip60(h) <==> lamin-A(h):Tip60(h) (binding) | DNA polymerase epsilon subunit 2(h) + Tip60(h) <==> DNA polymerase epsilon subunit 2(h):Tip60(h) (binding) | PTN4(h) + Tip60(h) <==> PTN4(h):Tip60(h) (binding) | RPTPsigma(h) + Tip60(h) <==> RPTPsigma(h):Tip60(h) (binding) | gsto1(h) + Tip60(h) <==> gsto1(h):Tip60(h) (binding) | p31-comet(h) + Tip60(h) <==> p31-comet(h):Tip60(h) (binding) | dleu1(h) + Tip60(h) <==> dleu1(h):Tip60(h) (binding) | Ari-2(h) + Tip60(h) <==> Ari-2(h):Tip60(h) (binding) | TCP-1eta(h) + Tip60(h) <==> TCP-1eta(h):Tip60(h) (binding) | POLR3F(h) + Tip60(h) <==> POLR3F(h):Tip60(h) (binding) | Snapin(h) + Tip60(h) <==> Snapin(h):Tip60(h) (binding) | C7orf20(h) + Tip60(h) <==> C7orf20(h):Tip60(h) (binding) | Cep215(h) + Tip60(h) <==> Cep215(h):Tip60(h) (binding) | CBX8(h) + Tip60(h) <==> CBX8(h):Tip60(h) (binding) | fam173a(h) + Tip60(h) <==> fam173a(h):Tip60(h) (binding) | DRLM(h) + Tip60(h) <==> DRLM(h):Tip60(h) (binding) | trrap(h) + TRCp120(h) + epc1(h) + epc2(h) + Tip60(h) + DMAP1(h) + Pontin52(h) + Reptin52(h) + BAF53a(h) + actin(h) + MRG15(h) + GAS41(h) + Eaf4(h) <==> trrap(h):TRCp120(h):epc1(h):epc2(h):Tip60(h):DMAP1(h):Pontin52(h):Reptin52(h):BAF53a(h):actin(h):MRG15(h):GAS41(h):Eaf4(h) (binding) | MRG15(h) + BAF53a(h) + Pontin52(h) + DMAP1(h) + Tip60(h) + epc1(h) + TRCp120(h) + trrap(h) + Eaf4(h) <==> MRG15(h):BAF53a(h):Pontin52(h):DMAP1(h):Tip60(h):epc1(h):TRCp120(h):trrap(h):Eaf4(h) (binding) | Htatip(h) --> Tip60(h) (expression). | pdcd5(h) --> Tip60(h) (increase of abundance) | AR-isoform1(h) + acetyl-CoA --Tip60(h)--> AR-isoform1(h){ace} + CoA (acetylation) | Tip60-alpha(h) + acetyl-CoA --> Tip60-alpha(h){ace} + CoA (acetylation; automodification) | Tip60-alpha(h) + 14-3-3gamma(h) <==> Tip60-alpha(h):14-3-3gamma(h) (binding) | Htatip(h) --> Tip60-alpha(h) (expression). | Htatip(h) --> Tip60-beta(h) (expression). | Htatip(h) --> Tip60-isoform3(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for KAT5 | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 65234565 - 65236565 | GSE27584 |
chr11 |
Promoter: 65234565 - 65236565 | GSE27584 |
chr11 |
Promoter: 65234565 - 65236565 | GSE27584 |
chr11 |
Promoter: 65234565 - 65236565 | Agilent_014791_44K |