Entrez Gene

Basic Information
Gene ID	10817
Name	FRS3
Synonymous	FRS2-beta\|FRS2B\|FRS2beta\|SNT-2\|SNT2;fibroblast growth factor receptor substrate 3;FRS3;fibroblast growth factor receptor substrate 3
Definition	FGFR substrate 3\|FGFR-signaling adaptor SNT2\|suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)
Position	6p21.1
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
FRS3(h) + TrkA-II(r) <==> FRS3(h):TrkA-II(r) (binding)
FRS3(h) + trkB-GP145(r) <==> FRS3(h):trkB-GP145(r) (binding)
FRS3(h) + trkC(r) <==> FRS3(h):trkC(r) (binding)
FRS3(h) + ATP --TrkA-II(r)--> FRS3(h){pY} + ADP (phosphorylation)
FRS3(h) + ATP --trkB-GP145(r)--> FRS3(h){pY} + ADP (phosphorylation)
FRS3(h) + ATP --trkC(r)--> FRS3(h){pY} + ADP (phosphorylation)
SHP-2(r) + Grb-2(r) + FRS3(h) <==> SHP-2(r):Grb-2(r):FRS3(h) (binding)
Grb-2(mo) + SHP-2(mo) + FRS3(h) <==> Grb-2(mo):SHP-2(mo):FRS3(h) (binding)
FRS3(h) + ATP --> FRS3(h){pY} + ADP (phosphorylation)
FRS3(h) --> FRS3(h) (expression).
FRS3(h) --> FRS3(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
2	N-myristoyl glycine (Probable).		Swiss-Prot 53.0