| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1654 |
Name | DDX3X |
Synonymous | CAP-Rf|DBX|DDX14|DDX3|HLP2;DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked;DDX3X;DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
Definition | ATP-dependent RNA helicase DDX3X|DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked|DEAD box protein 3, X-chromosomal|DEAD box, X isoform|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3|DEAD/H box-3|helicase-like protein 2 |
Position | Xp11.3-p11.23 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
Rock-1(h) + Aurora-A(h) + DDX3(h) + HLR2(h) <==> Rock-1(h):Aurora-A(h):DDX3(h):HLR2(h) (binding) | HCV-core(HCV) + DDX3(h) <==> HCV-core(HCV):DDX3(h) (binding) | EIF4A2(h) + DDX3(h) <==> EIF4A2(h):DDX3(h) (binding) | ESE-1(h) + DDX3(h) <==> ESE-1(h):DDX3(h) (binding) | SIAHBP1(h) + DDX3(h) <==> SIAHBP1(h):DDX3(h) (binding) | ILK(h) + DDX3(h) <==> ILK(h):DDX3(h) (binding) | RIP5(h) + DDX3(h) <==> RIP5(h):DDX3(h) (binding) | SAP18(h) + DDX3(h) <==> SAP18(h):DDX3(h) (binding) | TRAF6(h) + DDX3(h) <==> TRAF6(h):DDX3(h) (binding) | LC8(h) + DDX3(h) <==> LC8(h):DDX3(h) (binding) | cd40(h) + DDX3(h) <==> cd40(h):DDX3(h) (binding) | ddx1(h) + DDX3(h) + p72(h) + p68(h) + DDX15(h) + NF45(h) + HNRPH1(h) + EWS(h) + TDP43(h) + RN3(m.s.) + HNRPUL1(h) + raly(h) + SRPK1(h) + taf15(h) + TLS(h) + JKTBP(h) + hnRNPM(h) + SAF-A(h) + DRBP76(h) + Gy1(h) <==> ddx1(h):DDX3(h):p72(h):p68(h):DDX15(h):NF45(h):HNRPH1(h):EWS(h):TDP43(h):RN3(m.s.):HNRPUL1(h):raly(h):SRPK1(h):taf15(h):TLS(h):JKTBP(h):hnRNPM(h):SAF-A(h):DRBP76(h):Gy1(h) (binding) | DDX3X(h) --> DDX3(h) (expression). | HCV-Core-1B-Japanese(HCV1BJapan) + DDX3(h) <==> HCV-Core-1B-Japanese(HCV1BJapan):DDX3(h) (binding) | DDX3(h) + HCV-Core-1B-Japanese(HCV1BJapan) <==> DDX3(h):HCV-Core-1B-Japanese(HCV1BJapan) (binding) | DDX3(h) --> DDX3(h) (translocation) | DDX3(h) + HCV-core(HCV) <==> DDX3(h):HCV-core(HCV) (binding) | DDX3(h) --> DDX3(h) (translocation) | DDX3X(h) --> DDX3(h) (expression). | DDX3(h) --> DDX3(h) (translocation) | DDX3(h) --> DDX3(h) (translocation) |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylserine. | Swiss-Prot 53.0 | 69 | Phosphotyrosine. | Swiss-Prot 53.0 | 74 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 104 | Phosphotyrosine. | Swiss-Prot 53.0 | 343 | Phosphotyrosine. | Swiss-Prot 53.0 | 103 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 | 73 | Phosphoserine | 14729942 | Phospho.ELM 6.0 | 68 | Phosphotyrosine | 15592455;16094384 | Phospho.ELM 6.0 | 342 | Phosphotyrosine | 16097034 | Phospho.ELM 6.0 | 203 | Phosphothreonine (CDK1) | 16280325 | Phospho.ELM 6.0 | 322 | Phosphothreonine (CDK1) | 16280325 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chrX |
Promoter: 41076095 - 41078095 | Agilent_014791 |
chrX |
Promoter: 41076095 - 41078095 | GSE27584 |
chrX |
Promoter: 41076095 - 41078095 | Agilent_014791_44K |