General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 1788 |
Name | DNMT3A |
Synonymous | DNMT3A2|M.HsaIIIA|TBRS;DNA (cytosine-5-)-methyltransferase 3 alpha;DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha |
Definition | DNA (cytosine-5)-methyltransferase 3A|DNA MTase HsaIIIA|DNA cytosine methyltransferase 3A2 |
Position | 2p23 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A isoform-1(h) (expression). | DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A(h) (expression). | histone H3(m.s.) + S-adenosylmethionine --DNA (cytosine-5)-methyltransferase 3A(h)--> histone H3(m.s.){metK10} + S-adenosylhomocysteine (methylation) | DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A isoform-2(h) (expression). | DNMT3A(h) --> DNMT3A(h) (expression). | hsa-miR-29b --/ DNMT3A(h) (translational repression). | hsa-miR-29c --/ DNMT3A(h) (translational repression). | hsa-miR-29a --/ DNMT3A(h) (translational repression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
102 | Phosphoserine. | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr2 |
Promoter: 25417778 - 25419778 | Agilent_014791 |
chr2 |
Promoter: 25328184 - 25330184 | Agilent_014791 |
chr2 |
Promoter: 25418463 - 25420463 | Agilent_014791 |
chr2 |
Promoter: 25417778 - 25419778 | GSE27584 |
chr2 |
Promoter: 25328184 - 25330184 | GSE27584 |
chr2 |
Promoter: 25418463 - 25420463 | GSE27584 |
chr2 |
Promoter: 25418463 - 25420463 | GSE27584 |
chr2 |
Promoter: 25417778 - 25419778 | Agilent_014791_44K |