Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1788

Name

DNMT3A

Synonymous

DNMT3A2|M.HsaIIIA|TBRS;DNA (cytosine-5-)-methyltransferase 3 alpha;DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha

Definition

DNA (cytosine-5)-methyltransferase 3A|DNA MTase HsaIIIA|DNA cytosine methyltransferase 3A2

Position

2p23

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A isoform-1(h) (expression).
DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A(h) (expression).
histone H3(m.s.) + S-adenosylmethionine --DNA (cytosine-5)-methyltransferase 3A(h)--> histone H3(m.s.){metK10} + S-adenosylhomocysteine (methylation)
DNMT3A(h) --> DNA (cytosine-5)-methyltransferase 3A isoform-2(h) (expression).
DNMT3A(h) --> DNMT3A(h) (expression).
hsa-miR-29b --/ DNMT3A(h) (translational repression).
hsa-miR-29c --/ DNMT3A(h) (translational repression).
hsa-miR-29a --/ DNMT3A(h) (translational repression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

102Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

Promoter: 25417778 - 25419778Agilent_014791

chr2

Promoter: 25328184 - 25330184Agilent_014791

chr2

Promoter: 25418463 - 25420463Agilent_014791

chr2

Promoter: 25417778 - 25419778GSE27584

chr2

Promoter: 25328184 - 25330184GSE27584

chr2

Promoter: 25418463 - 25420463GSE27584

chr2

Promoter: 25418463 - 25420463GSE27584

chr2

Promoter: 25417778 - 25419778Agilent_014791_44K


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