| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 196 |
Name | AHR |
Synonymous | bHLHe76;aryl hydrocarbon receptor;AHR;aryl hydrocarbon receptor |
Definition | AH-receptor|ah receptor|aromatic hydrocarbon receptor|class E basic helix-loop-helix protein 76 |
Position | 7p15 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
AhR(h) --> CYP1A1(m) (DNA binding). | Hsp90(h) + AhR(h) <==> Hsp90(h):AhR(h) (binding). | AhR(h) + arnt(h) <==> AhR(h):arnt(h) (binding) | arnt(m) + AhR(h) <==> arnt(m):AhR(h) (binding). | BMAL1(h) + AhR(h) <==> BMAL1(h):AhR(h) (binding). | AhR(h) --> CYP1A1(h) (DNA binding; transactivation). | ITE + AhR(h) <==> ITE:AhR(h) (binding) | AhR(h) + CRM1(h) <==> AhR(h):CRM1(h) (binding) | AhR(h) + RelA-p65(h) <==> AhR(h):RelA-p65(h) (binding) | AhR(h) + pRb(h) <==> AhR(h):pRb(h) (binding) | RIP140(h) + AhR(h) <==> RIP140(h):AhR(h) (binding) | AIP(mo) + Hsp90(mo) + AhR(h) <==> AIP(mo):Hsp90(mo):AhR(h) (binding) | AhR(h) + SRC-1(h) <==> AhR(h):SRC-1(h) (binding) | AhR(h) + TIF2(m) <==> AhR(h):TIF2(m) (binding) | AhR(h) + SRC3(m) <==> AhR(h):SRC3(m) (binding) | AhR(h) + Sp1(r) <==> AhR(h):Sp1(r) (binding) | AhR(h) + ER-alpha(h) <==> AhR(h):ER-alpha(h) (binding) | AhR(h) + ERR1(h) <==> AhR(h):ERR1(h) (binding) | AhR(h) + COUP-TF1(h) <==> AhR(h):COUP-TF1(h) (binding) | AhR(h) + BRG1(h) <==> AhR(h):BRG1(h) (binding) | AhR(h) + Nedd8(h) <==> AhR(h):Nedd8(h) (binding) | AhR(h) --/ TFF1(h) (DNA binding; transrepression). | AhR(h) --/ HSPB1(h) (DNA binding; transrepression). | AhR(h) --> AhRR(m) (DNA binding; transactivation). | arnt(h) + AhR(h) + Sp1(h) <==> arnt(h):AhR(h):Sp1(h) (binding) | DAP3(h) + AhR(h) <==> DAP3(h):AhR(h) (binding) | AhR(h) --> SOD1(r) (DNA binding). | AhR(h) --> THBS1(h) (DNA binding). | AhR(h) --> CYP1A2(h) (DNA binding). | AhR(h) --> UGT1A10(h) (transactivation) | AhR(h) --> UGT1A8(h) (transactivation) | AhR(h) --> UGT1A9(h) (transactivation) | AhR(h) --> GSTA5(r) (DNA binding; transactivation). | AhR(h) --> ABCG2(h) (DNA binding; transactivation). | AHR(h) --> AhR(h) (expression). | AhR(h) --/ FOS(h) (DNA binding; transrepression). | AHR(h) --> AhR(h) (expression). | TBP(m.s.) + Ahr-xbb2(h) <==> TBP(m.s.):Ahr-xbb2(h) (binding) | TAF(II)135(m.s.) + Ahr-xbb2(h) <==> TAF(II)135(m.s.):Ahr-xbb2(h) (binding) | TAF(II)70(m.s.) + Ahr-xbb2(h) <==> TAF(II)70(m.s.):Ahr-xbb2(h) (binding) | SRC-1A(h) + Ahr-xbb2(h) <==> SRC-1A(h):Ahr-xbb2(h) (binding) | TIF2(m.s.) + Ahr-xbb2(h) <==> TIF2(m.s.):Ahr-xbb2(h) (binding) | AHR(h) --> Ahr-xbb2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
378 | Phosphotyrosine | 11032419 | Phospho.ELM 6.0 | 68 | Phosphoserine | 14985336 | Phospho.ELM 6.0 | 12 | Phosphoserine (PKC alpha) | 15063792 | Phospho.ELM 6.0 | 36 | Phosphoserine (PKC alpha) | 15063792 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr7 |
Promoter: 17303332 - 17305332 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 17303332 - 17305332 | GSE27584 |
chr7 |
Promoter: 17303332 - 17305332 | Agilent_014791_44K |
chr7 |
Promoter: 17303332 - 17305332 | PMID:16410262 |