Entrez Gene

Basic Information
Gene ID	2035
Name	EPB41
Synonymous	4.1R\|EL1\|HE;erythrocyte membrane protein band 4.1;EPB41;erythrocyte membrane protein band 4.1
Definition	EPB4.1\|P4.1\|band 4.1\|elliptocytosis 1, RH-linked\|erythrocyte surface protein band 4.1\|protein 4.1
Position	1p33-p32
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
alpha-tubulin(h) + 4.1R(h) <==> alpha-tubulin(h):4.1R(h) (binding)
4.1R(h) + alpha-tubulin(h) + numa1(h) <==> 4.1R(h):alpha-tubulin(h):numa1(h) (binding)
4.1R(h) + numa1(h) <==> 4.1R(h):numa1(h) (binding)
4.1R(h) + Dynein(h) <==> 4.1R(h):Dynein(h) (binding)
4.1R(h) + dynactin1(h) <==> 4.1R(h):dynactin1(h) (binding)
4.1R(h) + NuMA-isoform2(h) <==> 4.1R(h):NuMA-isoform2(h) (binding)
4.1R(h) + Myosin-9(h) <==> 4.1R(h):Myosin-9(h) (binding)
Cdk2(h) + 4.1R(h) <==> Cdk2(h):4.1R(h) (binding)
4.1R(h) + ValRS(h) <==> 4.1R(h):ValRS(h) (binding)
4.1R(h) + multifunctional protein ADE2(h) <==> 4.1R(h):multifunctional protein ADE2(h) (binding)
4.1R(h) + transgelin-2(h) <==> 4.1R(h):transgelin-2(h) (binding)
4.1R(h) + SIP(h) <==> 4.1R(h):SIP(h) (binding)
4.1R(h) + Enoyl-CoA hydratase-mitochondrial(h) <==> 4.1R(h):Enoyl-CoA hydratase-mitochondrial(h) (binding)
4.1R(h) + CRT(h) <==> 4.1R(h):CRT(h) (binding)
4.1R(h) + phosphoribosylformylglycinamidine synthase(h) <==> 4.1R(h):phosphoribosylformylglycinamidine synthase(h) (binding)
EPB41(h) --> 4.1R(h) (expression).
EPB41(h) --> 4.1R-isoform1(h) (expression).
EPB41(h) --> 4.1R-isoform2(h) (expression).
EPB41(h) --> 4.1R-isoform3(h) (expression).
EPB41(h) --> 4.1R-isoform4(h) (expression).
EPB41(h) --> 4.1R-isoform5(h) (expression).
EPB41(h) --> 4.1R-isoform6(h) (expression).
EPB41(h) --> 4.1R-isoform7(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
60	Phosphothreonine (by CDC2).		Swiss-Prot 53.0
540	Phosphoserine (By similarity).		Swiss-Prot 53.0
542	Phosphoserine (By similarity).		Swiss-Prot 53.0
555	Phosphoserine (By similarity).		Swiss-Prot 53.0
660	Phosphotyrosine (by EGFR).		Swiss-Prot 53.0
712	Phosphoserine (by CDC2).		Swiss-Prot 53.0
660	Phosphotyrosine (EGFR)	1647028	Phospho.ELM 6.0
759	O-linked	1:Inaba M. and Maede Y (1989) J. Biol. Chem., 264, 18149-18155. Medline: 90036892;2:Haltiwanger RS., Kelly WG., Roquemore EP., Blomberg MA., Dong LY.,Kreppel L., Chou TY. and Hart GW. (1992) Biochem. Soc. Trans., 20, 264-269. Medline: 93012378;Hart GW.	OGlycBase6.0
759	O-linked	1:Inaba M. and Maede Y (1989) J. Biol. Chem., 264, 18149-18155. Medline: 90036892;2:Haltiwanger RS., Kelly WG., Roquemore EP., Blomberg MA., Dong LY.,Kreppel L., Chou TY. and Hart GW. (1992) Biochem. Soc. Trans., 20, 264-269. Medline: 93012378;Hart GW.	OGlycBase6.0