Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2051

Name

EPHB6

Synonymous

HEP;EPH receptor B6;EPHB6;EPH receptor B6

Definition

ephrin type-B receptor 6|human kinase-defective Eph-family receptor protein|tyrosine-protein kinase-defective receptor EPH-6

Position

7q33-q35

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for EPHB6

Transcription Factors   [Top]

Regulation From TransFac database

EPHB6(h) + c-Cbl(h) <==> EPHB6(h):c-Cbl(h) (binding)
EPHB6(h) + Grb-2(h) <==> EPHB6(h):Grb-2(h) (binding)
EPHB6(h) + CrkL(h) <==> EPHB6(h):CrkL(h) (binding)
EPHB6(h) + crk(h) <==> EPHB6(h):crk(h) (binding)
EPHB6(h) + c-Cbl(h) <==> EPHB6(h):c-Cbl(h) (increase of dephosphorylation; binding)
SSAT(h) + EPHB6(h) <==> SSAT(h):EPHB6(h) (binding)
EPHB6(h) --> EPHB6(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

465N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 142261414 - 142263414Agilent_014791

chr7

Promoter: 142261414 - 142263414GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 142261414 - 142263414GSE27584

chr7

Promoter: 142261414 - 142263414Agilent_014791_44K


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