| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2120 |
Name | ETV6 |
Synonymous | TEL|TEL/ABL|THC5;ets variant 6;ETV6;ets variant 6 |
Definition | ETS translocation variant 6|ETS-related protein Tel1|TEL1 oncogene|ets variant gene 6 (TEL oncogene)|transcription factor ETV6 |
Position | 12p13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
STAT3(m.s.) + TEL1(h) <==> STAT3(m.s.):TEL1(h) (binding) | TEL1(h) + HDAC9(h) <==> TEL1(h):HDAC9(h) (binding) | ETV6(h) --> TEL1(h) (expression). | TEL1(h) + STAT3(m.s.) <==> TEL1(h):STAT3(m.s.) (binding) | TEL1(h) + HDAC9-7(h) <==> TEL1(h):HDAC9-7(h) (binding) | TEL1(h) --/ GBP(h) (DNA binding; transrepression). | ETV6(h) --> TEL1(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
22 | Phosphoserine. | Swiss-Prot 53.0 | 257 | Phosphoserine (by MAPK14). | Swiss-Prot 53.0 | 213 | Phosphoserine (MAPK3) | 15060146 | Phospho.ELM 6.0 | 257 | Phosphoserine (MAPK3) | 15060146 | Phospho.ELM 6.0 | 16 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 22 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr12 |
Promoter: 11692555 - 11694555 | Agilent_014791 |
chr12 |
Promoter: 11692555 - 11694555 | GoldenGate_Methylation_Cancer_Panel_I |
chr12 |
Promoter: 11692555 - 11694555 | GSE27584 |
chr12 |
Promoter: 11692555 - 11694555 | PMID:16435073 |