| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2131 |
Name | EXT1 |
Synonymous | EXT|LGCR|LGS|TRPS2|TTV;exostosin glycosyltransferase 1;EXT1;exostosin glycosyltransferase 1 |
Definition | Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase|Langer-Giedion syndrome chromosome region|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostoses (multiple) 1|exostosin 1|exostosin-1|glucuronosyl- |
Position | 8q24.11 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
2 exostosin-1(h) <==> (exostosin-1(h))2 (binding) | exostosin-2(m) + exostosin-1(h) <==> exostosin-2(m):exostosin-1(h) (binding) | exostosin-1(h) --> exostosin-1(h) (translocation) | EXT1(h) --> exostosin-1(h) (expression). | exostosin-1(h) --> exostosin-1(h) (translocation) | exostosin-1(h) + CNTF(h) <==> exostosin-1(h):CNTF(h) (binding) | exostosin-1(h) + Sh3p2(h) <==> exostosin-1(h):Sh3p2(h) (binding) | EXT1(h) --> exostosin-1(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
89 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 330 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr8 |
Promoter: 119192739 - 119194739 | Agilent_014791 |
chr8 |
Promoter: 119192739 - 119194739 | GoldenGate_Methylation_Cancer_Panel_I |
chr8 |
Promoter: 119192739 - 119194739 | GSE27584 |
chr8 |
Promoter: 119192739 - 119194739 | Agilent_014791_44K |
chr8 |
Promoter: 119192739 - 119194739 | PMID:15385438 |