Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2192

Name

FBLN1

Synonymous

FBLN|FIBL1;fibulin 1;FBLN1;fibulin 1

Definition

fibulin-1

Position

22q13.31

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Fibulin 1-D(h) + APP770(h) <==> Fibulin 1-D(h):APP770(h) (binding)
FBLN1(h) --> Fibulin 1-D(h) (expression).
FBLN1(h) --> Fibulin 1-A(h) (expression).
FBLN1(h) --> Fibulin 1-B(h) (expression).
APP695(h) + Fibulin 1-C(h) <==> APP695(h):Fibulin 1-C(h) (binding)
APP770(h) + Fibulin 1-C(h) <==> APP770(h):Fibulin 1-C(h) (binding)
Fibulin 1-C(h) + APP(mo) <==> Fibulin 1-C(h):APP(mo) (binding)
FBLN1(h) --> Fibulin 1-C(h) (expression).
MPG(h) + Fibulin 1(h) <==> MPG(h):Fibulin 1(h) (binding)
FBLN1(h) --> Fibulin 1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

98N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
535N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
539N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr22

Promoter: 44275883 - 44277883Agilent_014791

chr22

Promoter: 44275883 - 44277883GSE27584

chr22

Promoter: 44275883 - 44277883GSE27584

chr22

Promoter: 44275883 - 44277883GSE27584

chr22

Promoter: 44275883 - 44277883GSE27584

chr22

Promoter: 44275883 - 44277883Agilent_014791_44K


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