Entrez Gene

Basic Information
Gene ID	22933
Name	SIRT2
Synonymous	SIR2\|SIR2L\|SIR2L2;sirtuin 2;SIRT2;sirtuin 2
Definition	NAD-dependent deacetylase sirtuin-2\|NAD-dependent protein deacetylase sirtuin-2\|SIR2-like protein 2\|regulatory protein SIR2 homolog 2\|silent information regulator 2\|sir2-related protein type 2\|sirtuin type 2\|sirtuin-2
Position	19q13
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
SIRT2-isoform1(h) + ATP --> SIRT2-isoform1(h){pS} + ADP (phosphorylation)
SIRT2-isoform1(h) + ATP --Cdk1-isoform1(h):cyclinB1(h)--> SIRT2-isoform1(h){pS368} + ADP (phosphorylation)
SIRT2(h) --> SIRT2-isoform1(h) (expression).
SIRT2(h) + ATP --> SIRT2(h){p} + ADP (phosphorylation)
SIRT2(h) + n ubiquitin(h) --> SIRT2(h){ub}n (ubiquitination)
SIRT2(h) + SERS(h) <==> SIRT2(h):SERS(h) (binding)
SIRT2(h) + prohibitin-2(h) <==> SIRT2(h):prohibitin-2(h) (binding)
SPOP(h) + SIRT2(h) <==> SPOP(h):SIRT2(h) (binding)
SIRT2(h) + gys1(h) <==> SIRT2(h):gys1(h) (binding)
SIRT2(h) + Nogo(h) <==> SIRT2(h):Nogo(h) (binding)
SIRT2(h) + Keratin78(h) <==> SIRT2(h):Keratin78(h) (binding)
ELL(h) + SIRT2(h) <==> ELL(h):SIRT2(h) (binding)
SIRT2(h) --> SIRT2(h) (expression).
SIRT2(h){p} --Cdc14B(h)--> SIRT2(h) + p (dephosphorylation)
SIRT2(h) --> SIRT2-isoform2(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for SIRT2