Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

23468

Name

CBX5

Synonymous

HEL25|HP1|HP1A;chromobox homolog 5;CBX5;chromobox homolog 5

Definition

HP1 alpha homolog|HP1-ALPHA|HP1Hs alpha|antigen p25|chromobox homolog 5 (HP1 alpha homolog, Drosophila)|chromobox protein homolog 5|epididymis luminal protein 25|heterochromatin protein 1 homolog alpha|heterochromatin protein 1-alpha

Position

12q13.13

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

hist1h1b(h) + Hp1-alpha(h) <==> hist1h1b(h):Hp1-alpha(h) (binding)
RNF96(m.s.) + Hp1-alpha(h) <==> RNF96(m.s.):Hp1-alpha(h) (binding)
Cbx5(h) --> Hp1-alpha(h) (expression).
CTIP2-xbb4(m) + Hp1-alpha(h) <==> CTIP2-xbb4(m):Hp1-alpha(h) (binding)
Hp1-alpha(h) + DNA (cytosine-5)-methyltransferase 3B(h) <==> Hp1-alpha(h):DNA (cytosine-5)-methyltransferase 3B(h) (binding)
SUV39H1(h) + Hp1-alpha(h) <==> SUV39H1(h):Hp1-alpha(h) (binding)
Hp1-alpha(h) + ELOA2(h) <==> Hp1-alpha(h):ELOA2(h) (binding)
Hp1-alpha(h) + prr14(h) <==> Hp1-alpha(h):prr14(h) (binding)
Cbx5(h) --> Hp1-alpha(h) (expression).
histone H3(m.s.) + S-adenosylmethionine --Hp1-alpha(h)--> histone H3(m.s.){metK10} + S-adenosylhomocysteine (methylation)

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

11Phosphoserine.Swiss-Prot 53.0
12Phosphoserine.Swiss-Prot 53.0
13Phosphoserine.Swiss-Prot 53.0
14Phosphoserine.Swiss-Prot 53.0
92Phosphoserine (By similarity).Swiss-Prot 53.0
11Phosphoserine17081983Phospho.ELM 6.0
12Phosphoserine17081983Phospho.ELM 6.0
13Phosphoserine17081983Phospho.ELM 6.0
14Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for CBX5



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