| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2444 |
Name | FRK |
Synonymous | GTK|PTK5|RAK;fyn-related Src family tyrosine kinase;FRK;fyn-related Src family tyrosine kinase |
Definition | PTK5 protein tyrosine kinase 5|fyn-related kinase|nuclear tyrosine protein kinase RAK|protein-tyrosine kinase 5|tyrosine-protein kinase FRK |
Position | 6q21-q22.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
FRK(h) --> BSK(h) (expression). | ErbB2(h){pY1222} + BSK(h) <==> ErbB2(h){pY1222}:BSK(h) (binding) | ErbB4(h) + BSK(h) <==> ErbB4(h):BSK(h) (binding) | FRK(h) --> BSK(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
387 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 497 | Phosphotyrosine. | Swiss-Prot 53.0 | 497 | Phosphotyrosine | 15951569 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr6 |
Promoter: 116488114 - 116490114 | GoldenGate_Methylation_Cancer_Panel_I |
chr6 |
Promoter: 116488114 - 116490114 | GSE27584 |