Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

25898

Name

RCHY1

Synonymous

ARNIP|CHIMP|PIRH2|PRO1996|RNF199|ZCHY|ZNF363;ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase;RCHY1;ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

Definition

CH-rich interacting match with PLAG1|E3 ubiquitin-protein ligase Pirh2|RING finger and CHY zinc finger domain-containing protein 1|RING finger protein 199|androgen-receptor N-terminal-interacting protein|p53-induced protein with a RING-H2 domain|zinc fing

Position

4q21.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for RCHY1

Transcription Factors   [Top]

Regulation From TransFac database

PIRH2(h) + Tip60(h) <==> PIRH2(h):Tip60(h) (binding)
PIRH2(h) + n ubiquitin(h) --> PIRH2(h){ub(n)} (ubiquitination; automodification)
PIRH2(h) + ubiquitin(h) --> PIRH2(h){ub(1)} (ubiquitination; automodification)
PIRH2(h) + p53(h) <==> PIRH2(h):p53(h) (binding)
AR(h) + PIRH2(h) <==> AR(h):PIRH2(h) (binding)
PIRH2(h) --/ p53(h) (decrease of abundance)
PIRH2(h) --/ p21Cip1(h) (decrease of abundance)
Rchy1(h) --> PIRH2(h) (expression).
PIRH2(h) + AR-isoform1(h) <==> PIRH2(h):AR-isoform1(h) (binding)
HDAC1(m.s.) + PIRH2(h) <==> HDAC1(m.s.):PIRH2(h) (binding)
Rchy1(h) --> PIRH2(h) (expression).
HDAC1(m.s.) + ubiquitin(m.s.) --PIRH2(h)--> HDAC1(m.s.){ub} (ubiquitination)

Post Transcriptional Modification   [Top]

There is no record for RCHY1

Methylation Profile   [Top]

Chromosome

Location

Source

chr4

Promoter: 76658152 - 76660152GSE27584

chr4

Promoter: 76658152 - 76660152GSE27584

chr4

Promoter: 76658152 - 76660152GSE27584

chr4

Promoter: 76658152 - 76660152Agilent_014791_44K

chr4

Promoter: 76658152 - 76660152Agilent_014791


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