Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2626

Name

GATA4

Synonymous

ASD2|TACHD|TOF|VSD1;GATA binding protein 4;GATA4;GATA binding protein 4

Definition

GATA-binding factor 4|transcription factor GATA-4

Position

8p23.1-p22

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

GATA-4(h) --> Lct(r) (DNA binding; transactivation).
GATA-4(h) + CSX(h) <==> GATA-4(h):CSX(h) (binding)
GATA-4(h) --/ COL1A2(h) (DNA binding; transrepression).
GATA-4(h) --> EPHX1(h) (DNA binding; transactivation).
GATA-4(h) --> F10(h) (DNA binding; transactivation).
GATA-4(h) --> HSD3B1(h) (DNA binding).
GATA-4(h) --> CYP17A1(h) (DNA binding).
GATA-4(h) --> MUC4(h) (DNA binding).
GATA-4(h) --> CYP2E1(h) (DNA binding).
GATA-4(h) --> Epo(h) (DNA binding).
GATA4(h) --> GATA-4(h) (expression).
GATA-4(h) --> IL-5(h) (DNA binding; transregulation).
GATA4(h) --> GATA-4(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

262Phosphoserine11719519Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 11597662 - 11599662Agilent_014791

chr8

Promoter: 11597662 - 11599662GSE27584

chr8

Promoter: 11597662 - 11599662PMID:15585625


')