| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 27250 |
Name | PDCD4 |
Synonymous | H731;programmed cell death 4 (neoplastic transformation inhibitor);PDCD4;programmed cell death 4 (neoplastic transformation inhibitor) |
Definition | neoplastic transformation inhibitor protein|nuclear antigen H731|programmed cell death protein 4|protein 197/15a |
Position | 10q24 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
Regulation From TransFac database | Pdcd4(h) --> PDCD4(h) (expression). | hsa-miR-21 --/ PDCD4(h) (translational repression). | Pdcd4(h) --> H731(h) (expression). | EIF4A2(h) + H731(h) <==> EIF4A2(h):H731(h) (binding) | eIF-4AI(h) + H731(h) <==> eIF-4AI(h):H731(h) (binding) | Pdcd4(h) --> H731(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 76 | Phosphoserine. | Swiss-Prot 53.0 | 93 | Phosphothreonine. | Swiss-Prot 53.0 | 152 | Phosphotyrosine. | Swiss-Prot 53.0 | 457 | Phosphoserine. | Swiss-Prot 53.0 | 76 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 94 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 405 | Phosphotyrosine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 112620086 - 112622086 | Agilent_014791 |
chr10 |
Promoter: 112620086 - 112622086 | GSE27584 |
chr10 |
Promoter: 112620086 - 112622086 | GSE27584 |
chr10 |
Promoter: 112620086 - 112622086 | Agilent_014791_44K |