Entrez Gene

Basic Information
Gene ID	274
Name	BIN1
Synonymous	AMPH2\|AMPHL\|SH3P9;bridging integrator 1;BIN1;bridging integrator 1
Definition	amphiphysin II\|amphiphysin-like protein\|box dependant MYC interacting protein 1\|box-dependent myc-interacting protein 1\|myc box-dependent-interacting protein 1
Position	2q14
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Bin1-Isoform-1(h) + c-Myc(h) <==> Bin1-Isoform-1(h):c-Myc(h) (binding).
BIN1(h) --> Bin1-Isoform-1(h) (expression).
amphiphysin2b-1(h) + p73beta(h) <==> amphiphysin2b-1(h):p73beta(h) (binding)
BIN1(h) --> amphiphysin2b-1(h) (expression).
p73beta(h) --> CDKN1A(h) (transactivation)
amphiphysin2(h) + FAK1(r) <==> amphiphysin2(h):FAK1(r) (binding)
HCV-NS5A-1B(HCV1B) + amphiphysin2(h) <==> HCV-NS5A-1B(HCV1B):amphiphysin2(h) (binding)
POB1-isoform2(h) + amphiphysin2(h) <==> POB1-isoform2(h):amphiphysin2(h) (binding)
BIN1(h) --> amphiphysin2(h) (expression).
BIN1(h) --> Amphiphysin2A(h) (expression).
BIN1(h) --> Amphiphysin-IIB(h) (expression).
BIN1(h) --> Amphiphysin-IIC1(h) (expression).
BIN1(h) --> Amphiphysin-IIC2(h) (expression).
BIN1(h) --> Amphiphysin-IID(h) (expression).
HCV-NS5A-1B(HCV1B) + Amphiphysin-II2(h) <==> HCV-NS5A-1B(HCV1B):Amphiphysin-II2(h) (binding)
BIN1(h) --> Amphiphysin-II2(h) (expression).
BIN1(h) --> Amphiphysin-II3(h) (expression).
BIN1(h) --> Amphiphysin-BIN1(h) (expression).
BIN1(h) --> Amphiphysin-BIN1-10-13(h) (expression).
BIN1(h) --> Amphiphysin-BIN1-13(h) (expression).
BIN1(h) --> Amphiphysin-BIN1+12A(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
296	Phosphoserine.		Swiss-Prot 53.0
298	Phosphoserine.		Swiss-Prot 53.0
303	Phosphoserine.		Swiss-Prot 53.0
307	Phosphothreonine (By similarity).		Swiss-Prot 53.0
331	Phosphoserine.		Swiss-Prot 53.0
298	Phosphoserine	15302935;17081983	Phospho.ELM 6.0
296	Phosphoserine	15302935;17081983	Phospho.ELM 6.0
303	Phosphoserine	15302935;17081983	Phospho.ELM 6.0
307	Phosphothreonine	17081983	Phospho.ELM 6.0
331	Phosphoserine	17081983	Phospho.ELM 6.0